フェニルアラニルtRNA合成酵素、フェニルアラニルtRNAシンテターゼ
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- 1. 成人における皮膚筋炎および多発性筋炎の臨床症状 clinical manifestations of dermatomyositis and polymyositis in adults
- 2. 成人における皮膚筋炎および多発性筋炎の初期治療 initial treatment of dermatomyositis and polymyositis in adults
- 3. ヘキソースリン酸側路およびグルタチオン代謝関連疾患 related disorders of the hexose monophosphate shunt and glutathione metabolism
- 4. 炎症性ミオパチーの病因 pathogenesis of inflammatory myopathies
- 5. 皮膚筋炎および多発性筋炎における間質性肺疾患：臨床症状および診断 interstitial lung disease in dermatomyositis and polymyositis clinical manifestations and diagnosis
English Journal
- Molecular polygamy: The promiscuity of l-phenylalanyl-tRNA-synthetase triggers misincorporation of meta- and ortho-tyrosine in monoclonal antibodies expressed by Chinese hamster ovary cells.
- Popp O1, Larraillet V, Kettenberger H, Gorr IH, Hilger M, Lipsmeier F, Zeck A, Beaucamp N.
- Biotechnology and bioengineering.Biotechnol Bioeng.2015 Jun;112(6):1187-99. doi: 10.1002/bit.25528. Epub 2015 Feb 12.
- In-depth analytical characterization of biotherapeutics originating from different production batches is mandatory to ensure product safety and consistent molecule efficacy. Previously, we have shown unintended incorporation of tyrosine (Tyr) and leucine/isoleucine (Leu/Ile) at phenylalanine (Phe) p
- PMID 25545851
- Probiotic attributes of Lactobacillus fermentum isolated from human feces and dairy products.
- Archer AC1, Halami PM.
- Applied microbiology and biotechnology.Appl Microbiol Biotechnol.2015 May 26. [Epub ahead of print]
- The objective of this study was to characterize native Lactobacillus fermentum isolates for their probiotic attributes. Accordingly, 12 L. fermentum isolates selected from indigenous fermented dairy products and infant fecal samples were evaluated for their probiotic properties by in vitro and PCR m
- PMID 26004804
- Tailoring the substrate specificity of yeast phenylalanyl-tRNA synthetase toward a phenylalanine analog using multiple-site-specific incorporation.
- Kwon I1,2, Lim SI2.
- ACS synthetic biology.ACS Synth Biol.2015 May 15;4(5):634-43. doi: 10.1021/sb500309r. Epub 2014 Nov 17.
- A yeast phenylalanyl-tRNA synthetase variant with T415G mutation (yPheRS (T415G)) was rationally designed to recognize various phenylalanine (Phe) analogs allowing site-specific incorporation into an amber site of a protein in E. coli. However, the relaxed substrate specificity of yPheRS (T415G) led
- PMID 25268049
Japanese Journal
- Cloning of Bombyx mori phenylalanyl-tRNA synthetase and the generation of its mutant with relaxed amino acid specificity
- Teramoto Hidetoshi,Kojima Katsura
- Journal of insect biotechnology and sericology 79(2), 53-65, 2010-06-30
- NAID 10026709163
- Genetic, Enzymatic, and Structural Analyses of Phenylalanyl-tRNA Synthetase from Thermococcus kodakaraensis KOD1
- Shiraki Kentaro,Tsuji Masao,Hashimoto Yoshiteru [他],FUJIMOTO Kenzo,FUJIWARA Shinsuke,TAKAGI Masahiro,IMANAKA Tadayuki
- The journal of biochemistry 134(4), 567-574, 2003-10-01
- NAID 10012058479
- Genetic, Enzymatic, and Structural Analyses of Phenylalanyl-tRNA Synthetase from Thermococcus kodakaraensis KOD1
- Shiraki Kentaro,Tsuji Masao,Hashimoto Yoshiteru,Fujimoto Kenzo,Fujiwara Shinsuke,Takagi Masahiro,Imanaka Tadayuki
- The Journal of Biochemistry 134(4), 567-574, 2003
- … Phenylalanyl-tRNA synthetase from the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 (Tk-PheRS) was cloned. …
- NAID 130003534601
Related Links
- Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a phenylalanine-tRNA synthetase (PheRS) localized to the mitochondrion which consists of a ...
- FARSB FARSB A gene on chromosome 2q36.1 that encodes the beta subunit of phenylalanyl-tRNA synthetase, a heterotetramer formed by two alpha and two beta units.
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★リンクテーブル★
| リンク元 | 「フェニルアラニルtRNA合成酵素」「フェニルアラニルtRNAシンテターゼ」「phenylalanine-tRNA ligase」 |
| 関連記事 | 「synthetase」「tRNA」「tRNAs」 |
「フェニルアラニルtRNA合成酵素」
「フェニルアラニルtRNAシンテターゼ」
「phenylalanine-tRNA ligase」
「synthetase」
- n.
「tRNA」
[★] トランスファーRNA, transfer RNA, 転位RNA