WordNet

the tendency for a memory or idea to persist or recur without any apparent stimulus for it

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Enhanced attention and impulsive action following NMDA receptor GluN2B-selective antagonist pretreatment.

Higgins GA1, Silenieks LB2, MacMillan C3, Sevo J3, Zeeb FD4, Thevarkunnel S2.
Behavioural brain research.Behav Brain Res.2016 Sep 15;311:1-14. doi: 10.1016/j.bbr.2016.05.025. Epub 2016 May 11.
NMDA GluN2B (NR2B) subtype selective antagonists are currently in clinical development for a variety of indications, including major depression. We previously reported the selective NMDA GluN2B antagonists Ro 63-1908 and traxoprodil, increase premature responding in a 5-choice serial reaction time t
PMID 27180168

Belagodu AP1, Johnson AM2, Galvez R3.
Behavioural brain research.Behav Brain Res.2016 Sep 1;310:76-83. doi: 10.1016/j.bbr.2016.04.016. Epub 2016 Apr 30.
Fragile X Syndrome (FXS) is the leading form of inherited intellectual disability. It is caused by the transcriptional silencing of FMR1, the gene which codes for the Fragile X Mental Retardation Protein (FMRP). Patients who have FXS exhibit numerous behavioral and cognitive impairments, such as att
PMID 27142239

Optimization and pharmacological validation of a set-shifting procedure for assessing executive function in rats.

Troudet R1, Detrait E1, Hanon E1, Lamberty Y2.
Journal of neuroscience methods.J Neurosci Methods.2016 Aug 1;268:182-8. doi: 10.1016/j.jneumeth.2015.08.012. Epub 2015 Aug 19.
BACKGROUND: Set-shifting tests represent a reliable paradigm to assess executive functions in humans and animals. In the rat, set-shifting in a cross-maze is a recognized method. In this test, rats must learn an egocentric rule to locate food reinforcement. Once acquired, a second rule, based on vis
PMID 26296285