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1. ペニシリンの皮膚試験penicillin skin testing [show details]
… MDM reagents (ie, penicillin G, benzylpenicilloate, and benzylpenilloate). Skin testing with the minor determinant penicillin G alone is not the recommended approach. Skin testing with the aminopenicillins …
2. 即時型ペニシリンアレルギーの評価：皮膚反応試験に基づいた診断方法とその他のβ-ラクタム系抗菌薬との交差反応性試験allergy evaluation for immediate penicillin allergy skin test based diagnostic strategies and cross reactivity with other beta lactam antibiotics [show details]
…administered via a test dose procedure. One expert prefers the approach of skin testing to penicillin as well as carbapenems, and if penicillin testing is positive and carbapenem testing is negative, then …
3. ペニシリンアレルギー：即時型過敏反応penicillin allergy immediate reactions [show details]
… will perform skin testing: If skin testing is positive in a history-positive patient, then the allergy is confirmed (ie, evidence of continued skin test reactivity),… penicillin G). Oral penicillin V potassium has been used since the 1960s.…
4. ペニシリンアレルギーのある入院患者への抗菌薬の選択choice of antibiotics in penicillin allergic hospitalized patients [show details]
… follow-up for skin testing. Test dosing was performed similarly at all sites by nonallergist providers. Since guideline implementation, over 1000 test doses have been performed… Penicillins include the following: The natural penicillins – Penicillin V (oral), penicillin G (parenteral), benzathine penicillin (intramuscular),…
5. 連鎖球菌性咽頭炎の治療および予防treatment and prevention of streptococcal pharyngitis [show details]
… pharyngitis is high and testing results cannot be obtained rapidly, it is reasonable to start antibiotic treatment while test results are pending. If testing does not confirm the diagnosis,… we use oral penicillin V 500 mg two to three times daily for 10 days. Oral amoxicillin is also a reasonable option. For most children, we use either oral penicillin V or amoxicillin.…

English Journal

Multivariate optimization methods for in-situ growth of LDH/ZIF-8 nanocrystals on anodized aluminium substrate as a nanosorbent for stir bar sorptive extraction in biological and food samples.

Khoobi A, Salavati-Niasari M, Ghani M, Ghoreishi SM, Gholami A.
Food chemistry. 2019 Aug;288()39-46.
In-situ growth of zeolite imidazolate frameworks (ZIFs) on the surface of layered double hydroxides (LDHs) for preparation of porous nanocomposites is a favorable strategy to design potential materials in separation fields. In this research, nanoporous Zn-Al LDH/ZIF-8 composite was prepared by in-si
PMID 30902309

Pharmacy-Led β-Lactam Allergy Interview (BLAI) Reduces Duration of Fluoroquinolones Within a Community Hospital.

Covington EW, Baldwin BJ, Warren E.
The Annals of pharmacotherapy. 2019 Jun;53(6)588-595.
Patients with reported β-lactam allergies often receive broad-spectrum antimicrobials and have been shown to experience a variety of negative health consequences, such as increased mortality, costs, readmission, and adverse reactions. Current literature focuses on β-lactam allergy skin testing but
PMID 30688514

Dermatologically challenging syphilis presentation.

Katz AR, Johnson DW, Komeya AY, Tomas JE, Namiki TS, Kobayashi K.
International journal of STD & AIDS. 2019 Jun;30(7)707-709.
An atypical early primary syphilis case presentation with multiple umbilicated papular lesions on the penis and a nonreactive syphilis serology was misdiagnosed as molluscum contagiosum. Over a period of eight weeks, prior to dermatologic consultation, the papules enlarged, ulcerated, and healed. Ne
PMID 31112488

Japanese Journal

臨床研究・症例報告梅毒特異的PCR法により確定診断となった先天梅毒の1例

桜井博毅,堀越裕歩,中山周一
小児科臨床 = Japanese journal of pediatrics 72(5), 633-637, 2019-05
NAID 40021870826

Syphilitic Meningitis in a Human Immunodeficiency Virus-Negative Woman

Minato Saori,yamashita Takeshi,Yoshida Katsuyuki,Kawamura Ai,Watanabe Tamami,Ishii Akira,Fukuchi Takahiko,Sugawara Hitoshi,Kawase Masaaki,Demitsu Toshio
自治医科大学紀要 (41), 29-34, 2019-03
… Three months before admission, her heterosexual partner had been diagnosed with primary symptomatic syphilis with induration, but her initial serological screening tests for syphilis [rapid plasma reagin （RPR） test and Treponema pallidum hemagglutination （TPHA） test] were negative. … Antimicrobial treatment with penicillin G was continued for 2 weeks, after which the fever, posterior cervical pain, urodynia, and rash subsided, and the patient was discharged on hospital day 16. …
NAID 120006600922

当科におけるHelicobacter pylori除菌療法による薬疹の検討

山本容子,大原裕士郎,西崎絵里奈,細本宜士,吉岡希,村本睦子,磯貝理恵子,山田秀和
アレルギー 67(8), 1020-1026, 2018
<p>【目的・方法】本邦では保険適応の拡大に伴い，Helicobacter pylori（HP）除菌療法をうける患者が増加している．このためにHP除菌療法の薬疹が増加している．今回，我々は平成20年4月～平成28年3月までにHP除菌療法後に皮疹が出現し，当科を受診した28例について検討した．</p><p>【結果・考察】男性7例・女性21例であり，女性に多くみられ …
NAID 130007488784