WordNet

a substance from which another substance is formed (especially by a metabolic reaction)
a person who goes before or announces the coming of another (同)forerunner
cell that functions in the breakdown and resorption of bone tissue

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1. 進行性前立腺癌における骨転移の評価および管理 assessment and management of bone metastases in advanced prostate cancer
2. 前駆B細胞性急性リンパ芽球性白血病／リンパ腫の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of precursor b cell acute lymphoblastic leukemia lymphoma
3. アミロイド疾患の遺伝的要因 genetic factors in the amyloid diseases
4. 乳癌からの骨転移管理における破骨細胞阻害 osteoclast inhibition in the management of bone metastases from breast cancer
5. 腎不全における血管石灰化の生物学 biology of vascular calcification in renal failure

Evidence for the conservation of miR-223 in zebrafish (Danio rerio): Implications for function.

Roberto VP1, Tiago DM2, Gautvik K3, Cancela ML4.
Gene.Gene.2015 Jul 15;566(1):54-62. doi: 10.1016/j.gene.2015.04.022. Epub 2015 Apr 11.
MicroRNAs (miRNAs) are an abundant and conserved class of small RNAs, which play important regulatory functions by interacting with the 3' untranslated region (UTR) of target mRNAs. Through this mechanism, miR-223 was shown to regulate genes involved in mammalian haematopoiesis, both in physiologica
PMID 25869932

Oral administration of 5-hydroxytryptophan aggravated periodontitis-induced alveolar bone loss in rats.

Li X1, Wu X1, Ma Y2, Hao Z1, Chen S3, Fu T1, Chen H1, Wang H4.
Archives of oral biology.Arch Oral Biol.2015 May;60(5):789-98. doi: 10.1016/j.archoralbio.2015.01.015. Epub 2015 Feb 21.
OBJECTIVE: 5-Hydroxytryptophan (5-HTP) is the precursor of serotonin and 5-HTP has been widely used as a dietary supplement to raise serotonin level. Serotonin has recently been discovered to be a novel and important player in bone metabolism. As peripheral serotonin negatively regulates bone, the r
PMID 25766472

Adenoviral vector-mediated overexpression of osteoprotegerin accelerates osteointegration of titanium implants in ovariectomized rats.

Yin G1, Chen J2, Wei S3, Wang H1, Chen Q1, Lin Y1, Hu J1, Luo E4.
Gene therapy.Gene Ther.2015 Apr 14. doi: 10.1038/gt.2015.34. [Epub ahead of print]
This study investigated the efficacy of human osteoprotegerin (hOPG) transgene to accelerate osteointegration of titanium implant in ovariectomized (OVX) rats. Bone marrow stromal cells transduced with Ad-hOPG-EGFP could sustainedly express hOPG. Osteoclast precursor RAW264.7 cells treated by the hO
PMID 25871826