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1. 死体ドナー腎移植術の概要 overview of the surgery of deceased donor renal transplantation
2. 出産年齢の上昇に伴う受胎能保持の選択肢 fertility preserving options for women of advancing age
3. 膀胱切除術後の尿路変更および尿路再建 urinary diversion and reconstruction following cystectomy

English Journal

Mechanistic interrogation of combination bevacizumab/dual PI3K/mTOR inhibitor response in glioblastoma implementing novel MR and PET imaging biomarkers.

O'Halloran PJ1,2, Viel T3,4, Murray DW1, Wachsmuth L5, Schwegmann K3, Wagner S6, Kopka K6,7, Jarzabek MA1, Dicker P8, Hermann S3, Faber C5, Klasen T5, Schäfers M3,6, O'Brien D2, Prehn JH1, Jacobs AH3,9,10, Byrne AT11.
European journal of nuclear medicine and molecular imaging.Eur J Nucl Med Mol Imaging.2016 Mar 15. [Epub ahead of print]
PURPOSE: Resistance to bevacizumab (BEV) in glioblastoma is believed to occur via activation of molecular networks including the mTOR/PI3K pathway. Using an MR/PET molecular imaging biomarker approach, we investigated the response to combining BEV with the mTOR/PI3K inhibitor BEZ235.METHODS: Tumours
PMID 26975402

A chemical screen for medulloblastoma identifies quercetin as a putative radiosensitizer.

Lagerweij T1,2,3, Hiddingh L1,2,3, Biesmans D1,3, Crommentuijn MH3, Cloos J1, Li XN4, Kogiso M4, Tannous BA5, Vandertop WP2, Noske DP2,3, Kaspers GJ1, Würdinger T2,3,5, Hulleman E1,2,3.
Oncotarget.Oncotarget.2016 Mar 8. doi: 10.18632/oncotarget.7980. [Epub ahead of print]
Treatment of medulloblastoma in children fails in approximately 30% of patients, and is often accompanied by severe late sequelae. Therefore, more effective drugs are needed that spare normal tissue and diminish long-term side effects. Since radiotherapy plays a pivotal role in the treatment of medu
PMID 26967057

The STAT3 Inhibitor Galiellalactone Effectively Reduces Tumor Growth and Metastatic Spread in an Orthotopic Xenograft Mouse Model of Prostate Cancer.

Canesin G1, Evans-Axelsson S2, Hellsten R2, Sterner O3, Krzyzanowska A2, Andersson T4, Bjartell A5.
European urology.Eur Urol.2016 Mar;69(3):400-4. doi: 10.1016/j.eururo.2015.06.016. Epub 2015 Jul 2.
Signal transducer and activator of transcription 3 (STAT3) is known to be involved in the progression of prostate cancer (PCa) and is a key factor in drug resistance and tumor immunoescape. As a result, it represents a promising target for PCa therapy. We studied the effects of the STAT3 inhibitor g
PMID 26144873

Japanese Journal

Application of POLARIC (TM) fluorophores in an in vivo tumor model

Maishi Nako,Kawamoto Taisuke,Ohga Noritaka,Yamada Koji,Akiyama Kosuke,Yamamoto Kazuyuki,Osawa Takahiro,Hida Yasuhiro,Hida Kyoko
Oncology reports 30(4), 1695-1700, 2013-10
… A375-SM cells were labeled with these fluorescent probes and orthotopically implanted into nude mice. …
NAID 120005425362

G31P, an Antagonist against CXC Chemokine Receptors 1 and 2, Inhibits Growth of Human Prostate Cancer Cells in Nude Mice

Liu Xin,Peng Jing,Sun Wenchang,Yang Shufeng,Deng Guoying,Li Fang,Cheng Jya-Wei,Gordon John R.
The Tohoku Journal of Experimental Medicine 228(2), 147-156, 2012
… Additionally, G31P treatment of nude mice suppressed the growth of orthotopically transplanted tumor xenografts. …
NAID 130004460014

The therapeutic efficacy of S-1 against orthotopically implanted human pleural mesothelioma cells in severe combined immunodeficient mice

Trung The Van,Hanibuchi Masaki,Kakiuchi Soji,Sato Seidai,Kuramoto Takuya,Goto Hisatsugu,Mitsuhashi Atsushi,Nishioka Yasuhiko,Akiyama Shin-ichi,Sone Saburo
CANCER CHEMOTHERAPY AND PHARMACOLOGY 68(2), 497-504, 2011
NAID 120005207179

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