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1. 赤血球産生調節regulation of erythropoiesis [show details]
… form small colonies of erythroblasts in seven days of culture. The erythroid precursor or erythroblast pool represents about one-third… earliest recognizable forms These cells divide and mature through basophilic, polychromatic, and orthochromatic normoblast cells to form the reticulocyte and finally to the circulating mature erythrocyte; …
2. マラリアにおける貧血anemia in malaria [show details]
…symptoms. P. falciparum can invade red cells of all ages, including cells as early as orthochromatic erythroblasts , multiplies 10-fold within each 48-hour cycle, and expresses clonally variant antigens …
3. 鉄芽球性貧血の原因および病態生理causes and pathophysiology of the sideroblastic anemias [show details]
…anemias with defective heme synthesis, impaired hemoglobin production disrupts erythroblast maturation and the faulty erythroblasts are destroyed via mechanisms such as apoptosis, similar to thalassemias . …
4. 急性骨髄性白血病の分類classification of acute myeloid leukemia [show details]
…without AML-associated recurrent genetic abnormalities in whom erythroblasts account for >80 percent of the marrow cells. The erythroblasts are primarily at the pronormoblast stage and may have vacuolization …
5. 骨髄異形成症候群の臨床症状および診断clinical manifestations and diagnosis of the myelodysplastic syndromes [show details]
…sideroblasts, proving that this mutation leads to abnormal mitochondrial iron handling. SF3B1 mutant erythroblasts have coarser mitochondrial iron deposits than ring sideroblasts in MDS associated with wild type …

English Journal

Generation of an immortalized erythroid progenitor cell line from peripheral blood: a model system for the functional analysis of Plasmodium spp. invasion.

Scully EJ, Shabani E, Rangel GW, Grüring C, Kanjee U, Clark MA, Chaand M, Kurita R, Nakamura Y, Ferreira MU, Duraisingh MT.
American journal of hematology. 2019 May;().
Malaria pathogenesis is caused by the replication of Plasmodium parasites within the red blood cells (RBCs) of the vertebrate host. This selective pressure has favored the evolution of protective polymorphisms in erythrocyte proteins, a subset of which serve as cognate receptors for parasite invasio
PMID 31148215

Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation.

Trakarnsanga K, Ferguson D, Daniels DE, Griffiths RE, Wilson MC, Mordue KE, Gartner A, Andrienko TN, Calvert A, Condie A, McCahill A, Mountford JC, Toye AM, Anstee DJ, Frayne J.
Stem cell research & therapy. 2019 Apr;10(1)130.
Pluripotent stem cells are attractive progenitor cells for the generation of erythroid cells in vitro as have expansive proliferative potential. However, although embryonic (ESC) and induced pluripotent (iPSC) stem cells can be induced to undergo erythroid differentiation, the majority of cells fail
PMID 31036072

Biology of human primitive erythroblasts for application in noninvasive prenatal diagnosis.

Huang ZW, Fong CY, Gauthaman K, Sukumar P, Mahyuddin AP, Barrett AN, Bongso A, Choolani M.
Prenatal diagnosis. 2018 08;38(9)673-684.
Human primitive erythroblasts produced during early embryogenesis have been found in maternal circulation at early gestation and are considered good target cells for noninvasive prenatal diagnosis. We aimed to gain a better understanding of the biology of primitive erythroblasts and maximize their p
PMID 29876942

Japanese Journal

A simple method for enrichment of polychromatic erythroblasts from rat bone marrow, and their proliferation and maturation in vitro

Asano Hiroyuki,Deguchi Yoshihito,Kawamura Satoshi [他],INABA Mutsumi
Journal of toxicological sciences 36(4), 435-444, 2011-08-01
… During the culture period, cell proliferation and maturation to orthochromatic erythroblasts were observed, and intracellular heme contents were also increased. …
NAID 10029340237

ヒト免疫グロブリン製剤を投与した非再生性免疫介在性貧血の犬の1例

高橋義明,平川篤,大道嘉広,山本直人,田中美礼,吉田満洋,大塚浩平,桑原慶
動物臨床医学 20(3), 89-93, 2011
10歳3カ月齢，去勢雄のミニチュアダックスフントが1カ月前からの元気・食欲の低下を主訴に来院した。一般血液検査では重度の非再生性貧血と軽度の血小板減少症が認められた。骨髄検査では，赤芽球系細胞の過形成，正染性赤芽球以降の細胞の減少および単核細胞による赤血球と赤芽球の貪食像を認めたことから非再生性免疫介在性貧血と診断した。メチルプレドニゾロンによるパルス療法に対する反応が悪かったため，ヒト免疫グロブ …
NAID 130004493408

Studies on the DNA metabolism of erythroid cell. I. DNA level of erythroblastic nuclei of rabbit bone marrow, observation of normal, blood depleted, and phenylhydrazine anemias, and their recovery by red cell transfusion

Inoue Masanao
Acta Medicinae Okayama 24(1), 1970-02
… <p>For the purpose to reveal the changes in the metabolism of erythroblast in varied specialization stages the author observed the Feulgen DNA level of rabbit erythroblasts by microspectrophotometry. …
NAID 120002311376

「正染性赤芽球」

　　[★]

英: orthochromatic erythroblast
関: 赤血球

多染性赤芽球<-正染性赤芽球->網状赤血球

同: 490

-orthochromatic erythroblast

「NRBC-O」

　　[★] 正染性赤芽球 orthochromatic erythroblast

「orthochromatic」

　　[★]

adj.

正染性の

関: normochromatic、orthochromasia

リンク元	「正染性赤芽球」「NRBC-O」
関連記事	「orthochromatic」

匿名

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案内

案内

orthochromatic erythroblast

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★リンクテーブル★

「正染性赤芽球」

「NRBC-O」

「orthochromatic」