WordNet
- any bundle of nerve fibers running to various organs and tissues of the body (同)nervus
- optical properties; "the optics of a telescope"
- the branch of physics that studies the physical properties of light
- control of your emotions; "this kind of tension is not good for my nerves"
PrepTutorEJDIC
- 〈C〉『神経』 / 〈C〉《複数形で》『神経過敏』,いらだち / 〈U〉『勇気』,度胸(courage) / 〈U〉《時にa ~》厚かましさ,ずぶとさ;無礼 / 〈C〉葉脈;(昆虫の)翅脈(しみゃく) / 〈人,特に自分〉‘に'力を与える,‘を'元気づける
- 光学
- (・・・を)選ぶ《+『for』+『名』》;(・・・するほうを)選ぶ《+『to』 do》
- 目の;視覚の
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/08/08 08:56:03」(JST)
[Wiki en表示]
Optic nerve glioma |
|
Magnetic resonance image of a large retrobulbar optic nerve tumor causing massive proptosis. |
Classification and external resources |
Specialty |
oncology |
ICD-10 |
C72.3 |
MedlinePlus |
001024 |
eMedicine |
radio/486 |
MeSH |
C04.557.465.625.600.380.080.667 |
[edit on Wikidata]
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Optic nerve glioma (or optic glioma), a form of glioma which affects the optic nerve, is often one of the central nervous system manifestations of Neurofibromatosis 1.[1][2]
Optic gliomas are usually pilocytic tumors, and can involve the optic nerve or optic chiasm.[3] Optic gliomas are usually associated with neurofibromatosis type 1 in 30% of patients.[3]
Contents
- 1 Treatment
- 2 Prognosis
- 3 References
- 4 External links
Treatment
While radiation or chemotherapy may be helpful, treatment is often not necessary.[3] Optical gliomas often cannot be surgically resected. If no visual symptoms wait 6 months and then in 6 months only treat if there are symptoms (visual loss, eye pain), otherwise do not treat.[3]
Prognosis
Optic gliomas often have a shifting clinical course, with sporadic periods of vision loss separated by long periods of visual stability.[3] Optic gliomas rarely spontaneously regress.[3]
References
- ^ Huson, Susan Mary; Hughes, Richard Anthony Cranmer (1994). The neurofibromatoses: a pathogenetic and clinical overview. London: Chapman & Hall. 1.3.2:9. ISBN 0-412-38920-7.
- ^ Skelley, Tao Le, Vikas Bhushan, Nathan William. First aid for the USMLE step 2 CK (8th ed.). New York: McGraw-Hill Medical. ISBN 978-0-07-176137-6.
- ^ a b c d e f Goldman, Lee. Goldman's Cecil Medicine (24th ed.). Philadelphia: Elsevier Saunders. p. 1251. ISBN 1437727883.
External links
Nervous tissue tumors/NS neoplasm/Neuroectodermal tumor (ICD-O 9350–9589) (C70–C72, D32–D33, 191–192/225)
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Endocrine |
Sellar: |
- Craniopharyngioma
- Pituicytoma
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Other: |
|
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CNS |
Neuroepithelial
(brain tumors,
spinal tumors) |
Glioma |
Astrocyte |
- Astrocytoma
- Pilocytic astrocytoma
- Pleomorphic xanthoastrocytoma
- Subependymal giant cell astrocytoma
- Fibrillary astrocytoma
- Anaplastic astrocytoma
- Glioblastoma multiforme
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Oligodendrocyte |
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Ependyma |
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Choroid plexus |
- Choroid plexus tumor
- Choroid plexus papilloma
- Choroid plexus carcinoma
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Multiple/unknown |
- Oligoastrocytoma
- Gliomatosis cerebri
- Gliosarcoma
|
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Mature
neuron |
- Ganglioneuroma: Ganglioglioma
- Retinoblastoma
- Neurocytoma
- Dysembryoplastic neuroepithelial tumour
- Lhermitte–Duclos disease
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PNET |
- Neuroblastoma
- Esthesioneuroblastoma
- Ganglioneuroblastoma
- Medulloblastoma
- Atypical teratoid rhabdoid tumor
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Primitive |
|
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Meningiomas
(Meninges) |
- Meningioma
- Hemangiopericytoma
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Hematopoietic |
- Primary central nervous system lymphoma
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PNS: NST |
- Cranial and paraspinal nerves: Neurofibroma
- Neurofibrosarcoma
- Neurofibromatosis
- Neurilemmoma/Schwannoma
- Malignant peripheral nerve sheath tumor
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Note: Not all brain tumors are of nervous tissue, and not all nervous tissue tumors are in the brain (see brain metastasis).
|
UpToDate Contents
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English Journal
- Akt- or MEK-mediated mTOR inhibition suppresses Nf1 optic glioma growth.
- Kaul A1, Toonen JA1, Cimino PJ1, Gianino SM1, Gutmann DH1.
- Neuro-oncology.Neuro Oncol.2015 Jun;17(6):843-53. doi: 10.1093/neuonc/nou329. Epub 2014 Dec 21.
- BACKGROUND: Children with neurofibromatosis type 1 (NF1) develop optic pathway gliomas, which result from impaired NF1 protein regulation of Ras activity. One obstacle to the implementation of biologically targeted therapies is an incomplete understanding of the individual contributions of the downs
- PMID 25534823
- The impact of coexisting genetic mutations on murine optic glioma biology.
- Kaul A1, Toonen JA1, Gianino SM1, Gutmann DH1.
- Neuro-oncology.Neuro Oncol.2015 May;17(5):670-7. doi: 10.1093/neuonc/nou287. Epub 2014 Sep 21.
- BACKGROUND: Children with the neurofibromatosis type 1 (NF1) tumor predisposition syndrome are prone to the development of optic pathway gliomas resulting from biallelic inactivation of the NF1 gene. Recent studies have revealed the presence of other molecular alterations in a small portion of these
- PMID 25246427
Japanese Journal
- Diagnostic pitfall : Optic neuritis mimicking optic nerve glioma
- BERGMANN Markus,BRUCK Wolfgang,NEUBAUER Uwe,PROBST-COUSIN Stefan
- Neuropathology : official journal the Japanese Society of Neuropathology 29(4), 450-453, 2009-08-01
- NAID 10028191783
- Prevalence of Obesity, Hyperlipemia and Insulin Resistance in Children with Suprasellar Brain Tumors
- Adachi Masanori,Tsuchiya Takayoshi,Muroya Koji,Asakura Yumi,Sekido Ken-ichi,Sato Hironobu
- Clinical pediatric endocrinology 16(1), 1-9, 2007-01-00
- NAID 110006794336
Related Links
- A brain and nervous system (neurologic) examination reveals a loss of vision in one or both eyes. There may be changes in the optic nerve, including swelling or scarring of the nerve, or paleness and damage to the optic ...
- An optic nerve glioma is a type of brain tumor. There are multiple kinds of brain tumors. They are typically named after the kinds of cells they affect.According to the Johns Hopkins Brain Tumor Center, gliomas account ...
Related Pictures
★リンクテーブル★
[★]
- 英
- optic nerve glioma、optic glioma
- 関
- 小児視神経膠腫、視神経腫瘍
[★]
小児視神経膠腫
- 関
- optic glioma、optic nerve glioma
[★]
- 関
- choice、choose、elect、elective、option、optional、prefer、select、selection、selective
[★]
- 関
- nervi、nervous、nervus、neural、neuro、neuron
[★]
- 関
- ocular、vision、visual
[★]
- 関
- optical