WordNet
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/04/11 18:34:22」(JST)
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Oncogenic retroviridae proteins are retroviral proteins that have the ability to transform cells. They can induce sarcomas, leukaemias, lymphomas, and mammary carcinomas. These include the gag-onc fusion protein, rex, tax, v-fms, ras, v-myc, v-src, v-akt, v-cbl, v-crk, v-maf, v-abl, v-erbA, v-erbB, v-fos, v-mos, v-myb, v-raf, v-rel, and v-sis. The "v" prefix indicates viral genes which once originated as similarly named genes of the host species, but have since been altered through independent evolution as retroviral components. Not all retroviral proteins are oncogenic.[1] The phrase was introduced as a MeSH term in 1990, under which over 6000 primary scientific publications are indexed.[2]
See also
Oncogenic
References
- ^ Definition: retroviridae proteins, oncogenic from Online Medical Dictionary
- ^ "MeSH browser entry".
UpToDate Contents
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English Journal
- The PI3K/Akt pathway is involved in early infection of some exogenous avian leukosis viruses.
- Feng SZ, Cao WS, Liao M.SourceKey Laboratory of Animal Disease Control and Prevention of the Ministry of Agriculture, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, PR China.
- The Journal of general virology.J Gen Virol.2011 Jul;92(Pt 7):1688-97. Epub 2011 Mar 30.
- Avian leukosis virus (ALV) is an enveloped and oncogenic retrovirus. Avian leukosis caused by the members of ALV subgroups A, B and J has become one of the major problems challenging the poultry industry in China. However, the cellular factors such as signal transduction pathways involved in ALV inf
- PMID 21450945
- Antibodies to the envelope glycoprotein of human T cell leukemia virus type 1 robustly activate cell-mediated cytotoxic responses and directly neutralize viral infectivity at multiple steps of the entry process.
- Kuo CW, Mirsaliotis A, Brighty DW.SourceBiomedical Research Institute, College of Medicine Dentistry and Nursing, Ninewells Hospital, The University of Dundee, Dundee DD1 9SY, Scotland.
- Journal of immunology (Baltimore, Md. : 1950).J Immunol.2011 Jul 1;187(1):361-71. Epub 2011 Jun 6.
- Infection of human cells by human T cell leukemia virus type 1 (HTLV-1) is mediated by the viral envelope glycoproteins. The gp46 surface glycoprotein binds to cell surface receptors, including heparan sulfate proteoglycans, neuropilin 1, and glucose transporter 1, allowing the transmembrane glycopr
- PMID 21646298
Related Links
- Oncogenic retroviridae proteins are retroviral proteins that have the ability to transform cells. They can induce sarcomas, leukaemias, lymphomas, and mammary carcinomas. These include the gag-onc fusion protein, rex, tax, v-fms, ras, v-myc, ...
★リンクテーブル★
[★]
- 英
- oncogenic retroviridae protein
[★]
- 関
- carcinogenesis、carcinogenetic、carcinogenic、carcinogenicity、malignant transformation、oncogenesis、oncogenic transformation、transform
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レトロウイルス科
- 関
- oncornavirus、Oncovirinae、oncovirus、retrovirus、RNA tumor virus