- 関
- non-specific、nonspecific、off-target、unspecific
WordNet
- without specificity; "nonspecifically staining substances"
- not caused by a specific agent; used also of staining in making microscope slides; "nonspecific enteritis"
UpToDate Contents
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English Journal
- The hepatitis B virus (HBV) core protein enhances the transcription activation of CRE via the CRE/CREB/CBP pathway.
- Xiang A1, Ren F2, Lei X1, Zhang J1, Guo R1, Lu Z1, Guo Y1.
- Antiviral research.Antiviral Res.2015 Aug;120:7-15. doi: 10.1016/j.antiviral.2015.04.013. Epub 2015 May 1.
- We previously reported that hepatitis B virus core protein (HBc) can bind to the Enhancer I (Enh I) domain and can accumulate with transcription coactivator cAMP response element (CRE). This raises the possibility that HBc may interact with CRE/CREB and regulate CRE transcription activation. In this
- PMID 25936964
- Development of an ELISA-Based HDAC Activity Assay for Characterization of Isoform-Selective Inhibitors.
- Padige G1, Negmeldin AT1, Pflum MK2.
- Journal of biomolecular screening.J Biomol Screen.2015 Jul 31. pii: 1087057115598118. [Epub ahead of print]
- Histone deacetylase (HDAC) proteins are promising targets for cancer treatment, with several HDAC inhibitors used clinically as anticancer drugs. Most HDAC inhibitors nonspecifically interact with all or many of the 11 HDAC isoforms. Isoform-selective HDAC inhibitors would be useful tools to dissect
- PMID 26232305
- Structure of LacY with an α-substituted galactoside: Connecting the binding site to the protonation site.
- Kumar H1, Finer-Moore JS1, Kaback HR2, Stroud RM3.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2015 Jul 21;112(29):9004-9. doi: 10.1073/pnas.1509854112. Epub 2015 Jul 8.
- The X-ray crystal structure of a conformationally constrained mutant of the Escherichia coli lactose permease (the LacY double-Trp mutant Gly-46→Trp/Gly-262→Trp) with bound p-nitrophenyl-α-d-galactopyranoside (α-NPG), a high-affinity lactose analog, is described. With the exception of Glu-126
- PMID 26157133
Japanese Journal
- Dissection of Ire1 Functions Reveals Stress Response Mechanisms Uniquely Evolved in Candida glabrata
- Miyazaki Taiga,Nakayama Hironobu,Nagayoshi Yohsuke,Kakeya Hiroshi,Kohno Shigeru
- PLoS Pathogens 9(1), e1003160, 2013-01-31
- … It is known in metazoans that active Ire1 nonspecifically cleaves and degrades a subset of ER-localized mRNAs to reduce the ER load. …
- NAID 120005231146
- High-Frequency Electrodeless Quartz Crystal Microbalance Chip with a Bare Quartz Resonator Encapsulated in a Silicon Microchannel
- Kato Fumihito,Ogi Hirotsugu,Yanagida Taiji [他],Nishikawa Shintaro,Nishiyama Masayoshi,Hirao Masahiko
- Jpn J Appl Phys 50(7), 07HD03-07HD03-5, 2011-07-25
- … In addition, it is possible to reuse the device, because the quartz surfaces can adsorb receptor proteins nonspecifically, which can be removed by a washing procedure with a strong acid solution flowed in the microchannel. … We succeeded in detecting the human immunoglobulin G (hIgG) at a concentration of 6 μg/ml via the staphylococcal protein A (SPA) immobilized nonspecifically on the developed QCM chip in real time without any labeling. …
- NAID 150000057626
- Research and Development of On-site Decontamination System for Biological and Chemical Warfare Agents
- Seto Yasuo
- Journal of Health Science 57(4), 311-333, 2011
- … In addition, the present decontamination technologies are not effective, nonspecifically affecting the surrounding non-target materials. …
- NAID 130001001076
Related Links
- nonspecifically (ˌnɒnspɪˈsɪfɪkəlɪ) adv in a nonspecific way Thesaurus Antonyms Related Words Synonyms Legend: Adv. 1. nonspecifically - without specificity ... Walker and his traveling companion, Dane Freeman, were partners in ...
- Definition of nonspecifically in the AudioEnglish.org Dictionary. Meaning of nonspecifically. What does nonspecifically mean? Proper usage of the word nonspecifically. Information about nonspecifically in the AudioEnglish.org ...
Related Pictures
★リンクテーブル★
[★]
- 英
- nonspecific、non-specific、(遺伝子標的)off-target、unspecific、nonspecifically
- 関
- 非特異性、オフターゲット
[★]
- 関
- non-specific、nonspecifically、nonspecificity、off-target、unspecific
[★]
- 関
- nonspecific、nonspecifically、nonspecificity、off-target、unspecific
[★]
オフターゲットの、非特異的な
- 関
- non-specific、nonspecific、nonspecifically、unspecific
[★]
- 関
- non-specific、nonspecific、nonspecifically、off-target