WordNet

derived from organisms of a different but related species; "a heterologous graft"
not corresponding in structure or evolutionary origin (同)heterologic, heterological

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1. T-B-NK+ SCID：病因および遺伝学 t b nk scid pathogenesis and genetics
2. 重度複合型免疫不全（SCID）：特定の欠損 severe combined immunodeficiency scid specific defects
3. T-B-NK+ SCID：臨床症状、診断、および治療 t b nk scid clinical manifestations diagnosis and treatment
4. 症候群をきたす免疫不全症 syndromic immunodeficiencies
5. ゲノム疾患：概要 genomic disorders an overview

Generation of Stable Knockout Mammalian Cells by TALEN-Mediated Locus-Specific Gene Editing.

Mahata B1, Biswas K2.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2017;1498:107-120.
Precise and targeted genome editing using Transcription Activator-Like Effector Endonucleases (TALENs) has been widely used and proven to be an extremely effective and specific knockout strategy in both cultured cells and animal models. The current chapter describes a protocol for the construction a
PMID 27709571

Hoshida H1,2,3, Yarimizu T4, Akada R4,5,6.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2017;1472:237-46. doi: 10.1007/978-1-4939-6343-0_18.
Conventional gene synthesis is usually accompanied by sequence errors, which are often deletions derived from chemically synthesized oligonucleotides. Such deletions lead to frame shifts and mostly result in premature translational terminations. Therefore, in-frame fusion of a marker gene to the dow
PMID 27671945

Targeting Phosphatidylinositol 4-Kinase IIIα for Radiosensitization: A Potential Model of Drug Repositioning Using an Anti-Hepatitis C Viral Agent.

Kwon J1, Kim DH2, Park JM2, Park YH1, Hwang YH2, Wu HG3, Shin KH1, Kim IA4.
International journal of radiation oncology, biology, physics.Int J Radiat Oncol Biol Phys.2016 Nov 15;96(4):867-876. doi: 10.1016/j.ijrobp.2016.08.007. Epub 2016 Aug 20.
PURPOSE: To investigate which isotype of phosphatidylinositol 4-kinase (PI4K) may affect radiosensitivity and examine whether anti-hepatitis C viral (HCV) agents, some of which have been shown to inhibit PI4K IIIα activity, could be repositioned as a radiosensitizer in human cancer cells.METHODS AN
PMID 27788957

Nuclear localization of mouse Ku70 in interphase cells and focus formation of mouse Ku70 at DNA damage sites immediately after irradiation

, ,
Journal of Veterinary Medical Science advpub(0), 2015
… The classical nonhomologous DNA-end joining (NHEJ) (C-NHEJ) pathway repairs a predominant fraction of DSBs in mammalian cells. …
NAID 130005067036

Dynamic changes in subcellular localization of cattle XLF during cell cycle, and focus formation of cattle XLF at DNA damage sites immediately after irradiation

, ,
Journal of Veterinary Medical Science advpub(0), 2015
… Core factors of classical nonhomologous DNA-end joining (C-NHEJ) play a vital role in DSB repair. …
NAID 130005067034

C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion.

Sabouri Somayeh,Kobayashi Maki,Begum Nasim A,Xu Jianliang,Hirota Kouji,Honjo Tasuku
Proceedings of the National Academy of Sciences of the United States of America 111(6), 2253-2258, 2014-02-11
… To test this hypothesis, we analyzed the recombination junctions generated by AID C-terminal mutants and found that 0- to 3-bp microhomology junctions are relatively less abundant, possibly reflecting the defects of the classical nonhomologous end joining (C-NHEJ). …
NAID 120005395696