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母斑(ぼはん)(先天性のあざ・ほくろ・そばかすなど)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/01/07 05:53:49」(JST)

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Nevus sebaceous on the scalp

Nevus sebaceus or sebaceous nevus (the first term is its Latin name, the second term is its name in English; also known as an "Organoid nevus"^[1]^:661 and "Nevus sebaceus of Jadassohn"^[2]^:773) is a congenital, hairless plaque that typically occurs on the face or scalp.^[3] Such nevi are present at birth, or early childhood, affecting males and females of all races equally.^[4] The condition is named for an overgrowth of sebaceous glands in the area of the nevus.

Skin growths such as benign tumors and basal cell carcinoma can arise in sebaceous nevi, usually in adulthood. Rarely, sebaceous nevi can give rise to sebaceous carcinoma.^[5] However, the rate of such malignancies is now known to be less than had been estimated. For this reason, excision is no longer automatically recommended.^[6]

References

^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
^ Kovich O, Hale E (2005). "Nevus sebaceus". Dermatology Online Journal. 11 (4): 16. PMID 16403388.
^ Teng, Joyce M.C. Nevus sebaceous, University of Wisconsin Hospitals and Clinics Authority, last updated 16 November 2007.
^ Izumi M, Tang X, Chiu CS, et al. (November 2008). "Ten cases of sebaceous carcinoma arising in nevus sebaceus". J. Dermatol. 35 (11): 704–11. doi:10.1111/j.1346-8138.2008.00550.x. PMID 19120764.
^ Santibanez-Gallerani A, Marshall D, Duarte AM, Melnick SJ, Thaller S (September 2003). "Should nevus sebaceus of Jadassohn in children be excised? A study of 757 cases, and literature review". J. Craniofac. Surg. 14 (5): 658–60. doi:10.1097/00001665-200309000-00010. PMID 14501324.

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1. 脂腺母斑および脂腺母斑症候群 nevus sebaceous and nevus sebaceous syndrome
2. 新生児および乳児における皮膚および頭皮の良性病変 benign skin and scalp lesions in the newborn and young infant
3. 色素細胞性母斑（ほくろ）以外の良性色素性皮膚病変 benign pigmented skin lesions other than melanocytic nevi moles
4. 非定型母斑（異形成母斑） atypical dysplastic nevi
5. 後天性色素性母斑（ほくろ） acquired melanocytic nevi moles

English Journal

Frequent activating HRAS mutations in trichilemmoma.

Tsai JH1, Huang WC, Jhuang JY, Jeng YM, Cheng ML, Chiu HY, Kuo KT, Liau JY.
The British journal of dermatology.Br J Dermatol.2014 Nov;171(5):1073-7. doi: 10.1111/bjd.13143. Epub 2014 Sep 30.
BACKGROUND: Trichilemmoma is a benign follicular epithelial tumour exhibiting outer root sheath differentiation. It is associated with Cowden syndrome and naevus sebaceus (NS), but the pathogenesis of sporadic tumours is poorly understood. Recently, NS was found to be caused by postzygotic HRAS or K
PMID 24890286

Apocrine intraductal carcinoma in situ in nevus sebaceus: two case reports.

Llamas-Velasco M1, Requena L, Podda M, Weidenthaler-Barth B, Rütten A.
Journal of cutaneous pathology.J Cutan Pathol.2014 Oct 10. doi: 10.1111/cup.12394. [Epub ahead of print]
Ductal carcinoma in situ (DCIS) in the mammary glands consists of a proliferation of ductal luminal cells with preserved polarity but lacking the marked intercellular cohesion of hyperplastic cells. We report two cases of DCIS arising in the apocrine glandular structures of a nevus sebaceus (NS). Th
PMID 25302933

[Developmental abnormalities and nevi of the scalp.]

Behle V1, Hamm H.
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete.Hautarzt.2014 Oct 9. [Epub ahead of print]
Unusual congenital or early-onset skin lesions on the scalp often pose a diagnostic challenge particularly as the clinical evaluation may be hampered by dense hair growth. Thus, this paper provides a concise review on developmental abnormalities and nevi with exclusive or predominant scalp localizat
PMID 25298254