- 関
- neuropathologic、neuropathologically、neuropathology
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English Journal
- Effect of human umbilical cord blood derived lineage negative stem cells transplanted in amyloid-β induced cognitive impaired mice.
- Banik A1, Prabhakar S1, Kalra J2, Anand A3.
- Behavioural brain research.Behav Brain Res.2015 Sep 15;291:46-59. doi: 10.1016/j.bbr.2015.05.014. Epub 2015 May 17.
- Alzheimer's disease (AD) is pathologically characterized by extracellular deposition of insoluble amyloid-β (Aβ) plaques and intracellular tangles made up of phosphorylated tau in brain. Several therapeutic approaches are being carried out in animal AD models for testing their safety and efficacy
- PMID 25989508
- Enhanced astroglial Ca(2+) signaling increases excitatory synaptic strength in the epileptic brain.
- Álvarez-Ferradas C1, Morales JC1, Wellmann M1, Nualart F2, Roncagliolo M1, Fuenzalida M1, Bonansco C1.
- Glia.Glia.2015 Sep;63(9):1507-21. doi: 10.1002/glia.22817. Epub 2015 May 15.
- The fine-tuning of synaptic transmission by astrocyte signaling is crucial to CNS physiology. However, how exactly astroglial excitability and gliotransmission are affected in several neuropathologies, including epilepsy, remains unclear. Here, using a chronic model of temporal lobe epilepsy (TLE) i
- PMID 25980474
- Simultaneous changes in gray matter volume and white matter fractional anisotropy in Alzheimer's disease revealed by multimodal CCA and joint ICA.
- Ouyang X1, Chen K2, Yao L3, Hu B1, Wu X3, Ye Q1, Guo X4; Alzheimer’s Disease Neuroimaging Initiative.
- Neuroscience.Neuroscience.2015 Aug 20;301:553-62. doi: 10.1016/j.neuroscience.2015.06.031. Epub 2015 Jun 23.
- The prominent morphometric alterations of Alzheimer's disease (AD) occur both in gray matter and in white matter. Multimodal fusion can examine joint information by combining multiple neuroimaging datasets to identify the covariant morphometric alterations in AD in greater detail. In the current stu
- PMID 26116521
Japanese Journal
- Developmental Neurotoxicology: History and Outline of Developmental Neurotoxicity Study Guidelines
- Aoyama Hiroaki,Takahashi Naofumi,Shutoh Yasufumi,Motomura Atsuko,Crofton Kevin M.
- Food Safety 3(2), 48-61, 2015
- … Current internationally harmonized DNT study guidelines are thus intended to predict adverse effects of test compounds on the developing CNS by observing such postnatal parameters as motor activity, startle response, and learning and memory, as well as neuropathological alterations. …
- NAID 130005084364
- ステロイド療法が著効した慢性髄膜炎の1例―リウマチ性髄膜炎との鑑別の観点から―
- 森本 悟,髙尾 昌樹,櫻井 圭太,砂川 昌子,小宮 正,新井 冨生,金丸 和富,村山 繁雄
- 臨床神経学 advpub(0), 2015
- 症例は62歳の女性である.頭痛で発症し,3ヵ月にわたって進行する認知機能障害,発熱および炎症反応の持続を呈した.頭部MRI画像で皮質および白質に多発性病変をみとめ,造影後T1強調画像にて脳溝や脳室上衣に沿った造影効果をみとめた.認知機能障害およびMRI所見が急速に進行したため脳生検を施行.クモ膜下腔に多数の好中球浸潤および多核巨細胞よりなるリウマチ性髄膜炎類似の病理像をみとめるも,関節リウマチの症 …
- NAID 130005078355
- Rituximab-associated Progressive Multifocal Leukoencephalopathy Derived from Non-Hodgkin Lymphoma: Neuropathological Findings and Results of Mefloquine Treatment
- Sano Yasuteru,Nakano Yuta,Omoto Masatoshi,Takao Masaki,Ikeda Eiji,Oga Atsunori,Nakamichi Kazuo,Saijo Masayuki,Maoka Takashi,Sano Hironori,Kawai Motoharu,Kanda Takashi
- Internal Medicine 54(8), 965-970, 2015
- A 66-year-old man with non-Hodgkin lymphoma (NHL) developed progressive multifocal leukoencephalopathy (PML) after undergoing chemotherapy including rituximab. Although the administration of mefloquin …
- NAID 130005065265
Related Links
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