any organic substance that occurs in neural activity
English Journal
Analysis of γ-Aminobutyric Acid (GABA) Type A Receptor Subtypes Using Isosteric and Allosteric Ligands.
Olsen RW.
Neurochemical research.Neurochem Res.2014 Jul 12. [Epub ahead of print]
The GABAA receptors (GABAARs) play an important role in inhibitory transmission in the brain. The GABAARs could be identified using a medicinal chemistry approach to characterize with a series of chemical structural analogues, some identified in nature, some synthesized, to control the structural co
Uptake and Metabolism of Iron Oxide Nanoparticles in Brain Cells.
Petters C1, Irrsack E, Koch M, Dringen R.
Neurochemical research.Neurochem Res.2014 Jul 11. [Epub ahead of print]
Magnetic iron oxide nanoparticles (IONPs) are used for various applications in biomedicine, for example as contrast agents in magnetic resonance imaging, for cell tracking and for anti-tumor treatment. However, IONPs are also known for their toxic effects on cells and tissues which are at least in p
PPARγ and PGC-1α as Therapeutic Targets in Parkinson's.
Corona JC1, Duchen MR.
Neurochemical research.Neurochem Res.2014 Jul 10. [Epub ahead of print]
The peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated transcriptional factor that belongs to the nuclear hormone receptor superfamily. PPARγ was initially identified through its role in the regulation of glucose and lipid metabolism and cell differentiation. It also in
Journal of Veterinary Medical Science 76(10), 1353-1358, 2014
… We have previously reported that AmB changed the expression of neurotrophic factors in microglia and astrocytes (Motoyoshi et al., 2008, Neurochem. …
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