WordNet

make a groove in, or provide with a groove; "groove a vinyl record"
a long narrow furrow cut either by a natural process (such as erosion) or by a tool (as e.g. a groove in a phonograph record) (同)channel
(anatomy) any furrow or channel on a bodily structure or part (同)vallecula
of or relating to neurons; "neural network" (同)neuronal, neuronic
the cutting of spiral grooves on the inside of the barrel of a firearm (同)rifling
established as if settled into a groove or rut (同)well-grooved

PrepTutorEJDIC

(石・木・金属などに刻んだ)みぞ / (レコード盤面の)みぞ / 慣例,きまり / …‘に'みぞを掘る(刻む)
神経[系統]の

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/27 01:24:24」(JST)

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The neural groove is a shallow median groove of the neural plate between the neural folds of an embryo. The neural plate is a thick sheet of ectoderm surrounded on either side by the neural folds, two longitudinal ridges in front of the primitive streak of the developing embryo.^[1]

The groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or canal, the ectodermal wall of which forms the rudiment of the nervous system.

After the coalescence of the neural folds over the anterior end of the primitive streak, the blastopore no longer opens on the surface but into the closed canal of the neural tube, and thus a transitory communication, the neurenteric canal, is established between the neural tube and the primitive digestive tube. The coalescence of the neural folds occurs first in the region of the hind-brain, and from there extends forward and backward; toward the end of the third week the front opening (anterior neuropore) of the tube finally closes at the anterior end of the future brain, and forms a recess which is in contact, for a time, with the overlying ectoderm; the hinder part of the neural groove presents for a time a rhomboidal shape, and to this expanded portion the term sinus rhomboidalis has been applied. Before the neural groove is closed a ridge of ectodermal cells appears along the prominent margin of each neural fold; this is termed the neural crest or ganglion ridge, and from it the spinal and cranial nerve ganglia and the ganglia of the sympathetic nervous system are developed. By the upward growth of the mesoderm the neural tube is ultimately separated from the overlying ectoderm.

The cephalic end of the neural groove exhibits several dilatations, which, when the tube is closed, assume the form of three vesicles; these constitute the three primary cerebral vesicles, and correspond respectively to the future fore-brain (prosencephalon), mid-brain (mesencephalon), and hind-brain (rhombencephalon). The walls of the vesicles are developed into the nervous tissue and neuroglia of the brain, and their cavities are modified to form its ventricles. The remainder of the tube forms the medulla spinalis or spinal cord; from its ectodermal wall the nervous and neuroglial elements of the medulla spinalis are developed while the cavity persists as the central canal.^[1]

References

This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)

^ ^a ^b "The Neural Groove and Tube, in Gray's Anatomhy". Retrieved 2010-06-17. .

Additional images

Model of human embryo 1.3 mm. long.

External links

Swiss embryology (from UL, UB, and UF) iperiodembry/carnegie03
Embryology at UNSW Notes/week3_5
Diagram at embryology.med.unsw.edu.au

UpToDate Contents

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1. 神経管欠損症の超音波診断 ultrasound diagnosis of neural tube defects
2. 脊髄髄膜瘤（二分脊椎）の病態生理および臨床症状 pathophysiology and clinical manifestations of myelomeningocele spina bifida
3. 神経管欠損の出生前スクリーニングおよび診断 prenatal screening and diagnosis of neural tube defects
4. 原発性（先天性）脳ヘルニア primary congenital encephalocele
5. 神経管欠損および脳室拡大を除く中枢神経系異常の出生前診断 prenatal diagnosis of cns anomalies other than neural tube defects and ventriculomegaly

English Journal

Derivation of Schwann cell precursors from neural crest cells resident in bone marrow for cell therapy to improve peripheral nerve regeneration.

Shi H1, Gong Y2, Qiang L3, Li X4, Zhang S3, Gao J3, Li K4, Ji X4, Tian L4, Gu X5, Ding F6.
Biomaterials.Biomaterials.2016 May;89:25-37. doi: 10.1016/j.biomaterials.2016.02.029. Epub 2016 Feb 23.
We have previously successfully enriched post-migratory neural crest cells (NCCs) from postnatal rat bone marrow (BM). These BM-NCCs possess glial and neuronal differentiating potential. Based on the neural crest origin of Schwann cells (SCs), in this study, we aimed at using a straightforward proto
PMID 26946403

Macrophage precursor cells from the left atrial appendage of the heart spontaneously reprogram into a C-kit+/CD45- stem cell-like phenotype.

Leinonen JV1, Korkus-Emanuelov A1, Wolf Y2, Milgrom-Hoffman M3, Lichtstein D4, Hoss S1, Lotan C1, Tzahor E3, Jung S2, Beeri R5.
International journal of cardiology.Int J Cardiol.2016 Apr 15;209:296-306. doi: 10.1016/j.ijcard.2016.02.040. Epub 2016 Feb 4.
BACKGROUND: The developmental origin of the c-kit expressing progenitor cell pool in the adult heart has remained elusive. Recently, it has been discovered that the injured heart is enriched with c-kit(+) cells, which also express the hematopoietic marker CD45.METHODS AND RESULTS: In this study, we
PMID 26913371

High glucose suppresses embryonic stem cell differentiation into neural lineage cells.

Yang P1, Shen WB1, Albert Reece E2, Chen X1, Yang P3.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2016 Apr 1;472(2):306-12. doi: 10.1016/j.bbrc.2016.02.117. Epub 2016 Mar 3.
Abnormal neurogenesis occurs during embryonic development in human diabetic pregnancies and in animal models of diabetic embryopathy. Our previous studies in a mouse model of diabetic embryopathy have implicated that high glucose of maternal diabetes delays neurogenesis in the developing neuroepithe
PMID 26940741

Japanese Journal

1G42 伸長方向制御した神経軸索の衝撃引張ひずみ耐性評価

バイオエンジニアリング講演会講演論文集 2016(28), "1G42-1"-"1G42-4", 2016-01-09
NAID 110010052124

Prediction of T-Cell Epitope

Journal of pharmacological sciences 105(4), 299-316, 2007-12-20
NAID 10024316844

Reexamination of a primitive ornithomimosaur, Garudimimus brevipes Barsbold, 1981 (Dinosauria: Theropoda), from the Late Cretaceous of Mongolia

Canadian Journal of Earth Sciences 42(9), 1501-1521, 2005-09
NAID 120000956492

★リンクテーブル★

リンク元	「神経溝」
関連記事	「neural」「groove」

「神経溝」

Neural groove
	Human embryo—length, 2 mm. Dorsal view, with the amnion laid open. X 30.
Details
Latin	sulcus neuralis
Carnegie stage	9
Precursor	neural plate
Gives rise to	neural tube
Identifiers
Gray's	p.50
Code	TE E5.13.1.0.1.0.3
	Anatomical terminology