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1. 痘瘡ワクチンとしてのワクシニアウイルスvaccinia virus as the smallpox vaccine [show details]
… employ the vaccinia virus as a vector, the complications from vaccinia virus vaccination are still seen. Also, as described in a brief report, people can accidentally be exposed to recombinant vaccinia viruses …
2. 研究環境におけるワクシニアウイルスvaccinia virus in the research setting [show details]
…researchers who are working with vaccinia virus who were never vaccinated as children. Issues related to vaccinia virus in the research setting will be reviewed here. Vaccinia virus as the smallpox vaccine …
3. サル痘monkeypox [show details]
…smallpox immunization (ie, vaccinia virus vaccine), the World Health Organization (WHO) monitored subsequent human monkeypox activity. The WHO was concerned that elimination of the vaccinia virus vaccine, which …
4. 心筋心膜炎myopericarditis [show details]
…isolated from patients with vaccinia-associated myopericarditis; as a result, an autoimmune mechanism is thought to be responsible for most cases . The clinical presentation of vaccinia-associated myopericarditis …
5. 急性膵炎のマネージメントmanagement of acute pancreatitis [show details]
…fluid collection, pancreatic pseudocyst, acute necrotic collection, and walled-off necrosis . While acute peripancreatic fluid collections and acute necrotic collections may develop less than four weeks …

English Journal

The Virulence of Different Vaccinia Virus Strains Is Directly Proportional to Their Ability To Downmodulate Specific Cell-Mediated Immune Compartments .

de Freitas LFD, Oliveira RP, Miranda MCG, Rocha RP, Barbosa-Stancioli EF, Faria AMC, da Fonseca FG.
Journal of virology. 2019 Mar;93(6).
Vaccinia virus (VACV) is a notorious virus for a number of scientific reasons; however, most of its notoriety comes from the fact that it was used as a vaccine against smallpox, being ultimately responsible for the eradication of that disease. Nonetheless, many different vaccinia virus strains have
PMID 30567985

Recovery of recombinant infectious hematopoietic necrosis virus strain Sn1203 using the mammalian cell line BHK-21.

Zhao JZ, Xu LM, Zhang ZY, Liu M, Cao YS, Yin JS, Liu HB, Lu TY.
Journal of virological methods. 2019 03;265()84-90.
Reverse genetics systems are powerful tools for understanding the virulence mechanisms and gene functions of negative-sense RNA viruses. The reverse genetics systems commonly used for recombinant infectious hematopoietic necrosis virus (IHNV) are based on vaccinia virus infection. To avoid the poten
PMID 30615899

MTBVAC-Based TB-HIV Vaccine Is Safe, Elicits HIV-T Cell Responses, and Protects against in Mice.

Broset E, Saubi N, Guitart N, Aguilo N, Uranga S, Kilpeläinen A, Eto Y, Hanke T, Gonzalo-Asensio J, Martín C, Joseph-Munné J.
Molecular therapy. Methods & clinical development. 2019 Jun;13()253-264.
The tuberculosis (TB) vaccine MTBVAC is the only live-attenuated ()-based vaccine in clinical development, and it confers superior protection in different animal models compared to the current vaccine, BCG ( bacillus Calmette-Guérin). With the aim of using MTBVAC as a vector for a dual TB-HIV vacc
PMID 30859110

Japanese Journal

SKIN REACTIONS TO VACCINIA VIRUS INFECTION IN THE RABBITS IMMUNIZED WITH VACCINIA-SOLUBLE EARLY ANTIGEN

湯浅田鶴子,茅野文利,鶴原喬
Ｊａｐａｎｅｓｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ　ａｎｄ　Ｂｉｏｌｏｇｙ 36(3), 147-156, 1983
… Rabbits were immunized with vaccinia-soluble early antigen (Es antigen) in Freund's complete adjuvant (FCA) . … Circulating neutralizing antibody was not induced, but CF antibody against the soluble antigens of vaccinia-infected cells was induced. … By intradermal inoculation of vaccinia virus, erythema developed early at the site of inoculation and enlarged up to 3 days post infection (p.i.) . …
NAID 130003953359

牛痘Virusの孵化鶏卵培養に関する研究

目黒春枝
札幌医学雑誌 4(6), 415-420, 1953-12
… The testical lymph of vaccinia virus can be cultured in the developing chick embryo through 19 passages without any detectable reduction of minimal infective dose. … With adding antiserum to the infected chorio-allantoic membrane, localization of necrotic lesions and increased infiltration of leukocytes were observed. …
NAID 120005942038

痘毒接種家兎の病理組織学的変化に就て

岸哲雄
ＶＩＲＵＳ 3(2), 108-118, 1953
… Following this reaction the monocytic infiltration appears in the papilla, growing gradually to the depth of the corium along the hair follicule and reaching to the reticular layer.<br>3) After 8 days the hemorrhagic inflammation appears in the monocyte infiltrated corium which makes this leisions necrotic and causes to fall off. …
NAID 130003854211