WordNet

any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions

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Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma.

Li XY1, Zhao Y1, Sun MG1, Shi JF1, Ju RJ1, Zhang CX1, Li XT1, Zhao WY1, Mu LM1, Zeng F1, Lou JN2, Lu WL3.
Biomaterials.Biomaterials.2014 Jul;35(21):5591-604. doi: 10.1016/j.biomaterials.2014.03.049. Epub 2014 Apr 13.
Invasive brain glioma is the most lethal type of cancer and is highly infiltrating. This leads to an extremely poor prognosis and makes complete surgical removal of the tumor virtually impossible. Non-penetration of therapeutic drugs across the blood-brain barrier (BBB), brain cancer stem cells (CSC
PMID 24726749

Kisspeptin-10 induces endothelial cellular senescence and impaired endothelial cell growth.

Usui S, Iso Y, Sasai M, Mizukami T, Mori H1, Watanabe T2, Shioda S3, Suzuki H1.
Clinical science (London, England : 1979).Clin Sci (Lond).2014 Jul;127(1):47-55. doi: 10.1042/CS20130505.
The KPs (kisspeptins) are a family of multifunctional peptides with established roles in cancer metastasis, puberty and vasoconstriction. The effects of KPs on endothelial cells have yet to be determined. The aim of the present study was to investigate the effects of KP-10 on endothelial cell growth
PMID 24405415

Coates CJ1, Nairn J2.
Developmental and comparative immunology.Dev Comp Immunol.2014 Jul;45(1):43-55. doi: 10.1016/j.dci.2014.01.021. Epub 2014 Jan 31.
Substantial evidence gathered recently has revealed the multiple functionalities of hemocyanin. Contrary to previous claims that this ancient protein is involved solely in oxygen transport within the hemolymph of invertebrates, hemocyanin and hemocyanin-derived peptides have been linked to key aspec
PMID 24486681

Hydratase Activities of Green Fluorescent Protein Tagged Human Multifunctional Enzyme Type 2 Hydratase Domain and its Variants

MAEJIMA Yasunori,NAKATSUGAWA Hiroki,ICHIDA Daiki,MAEJIMA Mayumi,AOYAGI Yasuo,MAOKA Takashi,ETOH Hideo
Bioscience, biotechnology, and biochemistry 75(9), 1708-1712, 2011-09-23
… Fermented buckwheat sprouts (FBS) are used as multifunctional foods. … We searched for the functional components, and nicotianamine (NA) and 2″-hydroxynicotianamine (HNA) were identified as angiotensin I-converting enzyme (ACE) inhibitors. …
NAID 10029757034

Transdifferentiation of Epidermis to Mucous Epithelium by Retinol Accompanies Increase in Transglutaminase 2/Gh and Decrease in Transglutaminase 3

Obinata Akiko,Akimoto Yoshihiro
Biological and Pharmaceutical Bulletin 34(8), 1227-1230, 2011
… The most characteristic enzyme function of TG family is calcium-dependent transamidation activity (transamidase) that introduces inter or intramolecular ε-(γ-glutamyl)lysine cross-links into the protein. … TG2/Gh is a multifunctional protein and ubiquitously expressed member of transglutaminase family that has been implicated in a variety of biological processes. …
NAID 130000936591