Current views on the potential for development of a HIV vaccine.
Cohen KW1, Frahm N1,2.
Expert opinion on biological therapy.Expert Opin Biol Ther.2017 Mar;17(3):295-303. doi: 10.1080/14712598.2017.1282457. Epub 2017 Jan 23.
INTRODUCTION: Despite many recent advances in the HIV prevention landscape, an effective vaccine remains the most promising tool to end the HIV-1 pandemic. Areas covered: This review summarizes past HIV vaccine efficacy trials and current vaccine strategies as well as new approaches about to move in
Human Cytomegalovirus (HCMV)-Specific CD4+ T Cells Are Polyfunctional and Can Respond to HCMV-Infected Dendritic Cells In Vitro.
Jackson SE1, Sedikides GX2, Mason GM2, Okecha G2, Wills MR1.
Journal of virology.J Virol.2017 Feb 28;91(6). pii: e02128-16. doi: 10.1128/JVI.02128-16. Print 2017 Mar 15.
Human cytomegalovirus (HCMV) infection and periodic reactivation are generally well controlled by the HCMV-specific T cell response in healthy people. While the CD8+ T cell response to HCMV has been extensively studied, the HCMV-specific CD4+ T cell effector response is not as well understood, espec