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relating to or containing mucin

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/01/09 15:12:16」(JST)

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Mucinous cystadenoma is a type of tumor in the cystadenoma grouping.

By location, they are most commonly found in:

   Bile duct cystadenoma 
   Endometrioid cystadenoma 
   Appendix mucinous cystadenoma
     (See cystadenoma  )

Ovarian tumors comprise one group of mucinous cystadenomas. These include: 1. Epithelial tumors (65-75%) - serous or mucinous cystadenoma/carcinoma, clear cell carcinoma, Brenner tumor 2. Germ cell tumors (15%) - dysgerminoma, embryonal cell cancer, choriocarcinoma, teratoma 3. Sex-chord-stromal tumors (5-10%) - granulosa cell tumor, thecoma, fibroma 4. Metastatic tumors (10%) - uterine, stomach, colon, breast, lymphoma

Mucinous cystadenomas make up 15-20% of all ovarian tumors. They often become very large and can extend up into the abdomen. Pseudomyxoma peritonei can result if the tumor ruptures and spills its contents into the abdomen.

These tumors are usually evaluated using ultrasound, CT scan, or MRI. Findings on imaging studies are nonspecific. These ovarian tumors are usually multi-septated, cystic masses with thin walls. They also contain varying amounts of solid tissue which consists of proliferating stromal tissue, papillae, or malignant tumor cells.

Mucinous cystadenomas are divided into three categories: benign, borderline, and malignant. Survival is largely dependent on the histology of the tumor, with a 10 year survival rate of 100% for benign tumors, 60% for borderline tumors, and only 34% for the malignant subtype. There is some difference in ages of the peak incidence for the different subtypes with considerable overlap as described below. In general, benign tumors tend to present earlier, while malignant tumors are often seen later in life.

Benign mucinous cystadenomas compose 80% of mucinous ovarian tumors and 20-25% of benign ovarian tumors overall. The peak incidence occurs between 30-50 years of age. Benign tumors are bilateral in 5-10% of cases.

Borderline mucinous cystadenomas make up about 10% of mucinous ovarian neoplasms and are bilateral in 10% of cases.

Malignant mucinous cystadenoms are rare, and encompass 10% of mucinous ovarian tumors and 5-10% of primary malignant ovarian neoplasms overall. They are bilateral in 15-30% of cases and have a peak incidence between 40-70 years of age. It can present in the ovary.^[1]

References[edit]

^ Turkyilmaz E, Korucuoglu U, Kutlusoy F, et al (March 2009). "Recurrent mucinous cystadenoma: a laparoscopic approach". Arch. Gynecol. Obstet. 279 (3): 387–9. doi:10.1007/s00404-008-0718-0. PMID 18584185. Cite uses deprecated parameters (help)

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1. 付属器腫瘤の鑑別診断 differential diagnosis of the adnexal mass
2. 虫垂粘液嚢胞 appendiceal mucoceles
3. 膵嚢胞性腫瘍 pancreatic cystic neoplasms
4. 上皮性の卵巣癌、卵管癌、および腹膜癌：病理 epithelial carcinoma of the ovary fallopian tube and peritoneum histopathology
5. 肝嚢胞性病変の診断およびマネージメント diagnosis and management of cystic lesions of the liver

English Journal

Differentiation of mucinous cystic neoplasm and cystic changes associated with pancreatic adenocarcinoma.

Ha TH, Jeon TJ, Park JY.SourceDivision of Gastroenterology Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Republic of Korea.
BMJ case reports.BMJ Case Rep.2013 Nov 5;2013. pii: bcr2013201208. doi: 10.1136/bcr-2013-201208.
A 63-year-old woman presented to the hospital with persistent nausea, dyspepsia and weight loss for 6 months. Abdomen CT showed a low-attenuation mass, approximately 7.6 cm diameter, in the region of the body and tail of the pancreas. Cystic lesions, 5.5×4.9 cm and 4.6×3.7 cm in size, were observe
PMID 24194164

Giant biliary mucinous cystadenoma of the liver.

Grubor NM, Colovic RB, Atkinson HD, Micev MT.SourceFirst Surgical Clinic, Clinical Center of Serbia, Belgrade University. School of Medicine, Koste Todorovica 6, Belgrade 11000, Serbia.
Annals of hepatology.Ann Hepatol.2013 Nov-Dec;12(6):979-83.
Biliary mucinous cystadenomas (BMC) of the liver are rare benign cystic tumors, however an estimated 20% undergo malignant transformation. They have recently been redefined as mucinous cystic neoplasms in the 2010 WHO classification. The preferred treatment is through radical resection, as there are
PMID 24114831

[Will molecular diagnostics become established in pancreatic pathology?].

Sipos B, Sperveslage J.SourceAllgemeine Pathologie und Pathologische Anatomie, Institut für Pathologie und Neuropathologie, Universitätsklinikum Tübingen, Liebermeisterstr. 8, 72076, Tübingen, Deutschland, bence.sipos@med.uni-tuebingen.de.
Der Pathologe.Pathologe.2013 Nov;34 Suppl 2:214-20. doi: 10.1007/s00292-013-1865-z.
Genetic alterations of solid and cystic tumors of the pancreas have been increasingly more characterized over the last few years. Pancreatic ductal adenocarcinoma (PDAC) carries numerous point mutations and, to a lesser extent, deletions and amplifications of genes that are associated with at least
PMID 24196616

Japanese Journal

症例報告血清CEA高値を契機に発見された虫垂粘液嚢胞腺腫の2例

武藤桃太郎,武藤瑞恵,石川千里 [他]
日本農村医学会雑誌 63(1), 49-56, 2014-05
NAID 40020155067

尿膜管由来と思われた境界悪性粘液性嚢胞腺腫の1例

矢口貴一郎,五明良仁,斉藤拓康,池野龍雄,坂口博美,宮本英雄
日本臨床外科学会雑誌 75(5), 1418-1422, 2014
症例は75歳，男性．PSA高値を認め，前立腺癌の疑いで当院泌尿器科に紹介受診となり，膀胱前上方に接する嚢胞性腫瘤が認められたため手術目的で外科紹介となった．術前精査の結果，転移性腫瘍の可能性は低かった．また，腫瘤の良悪性の診断がつかなかったため，確定診断の目的で摘出手術を施行した．腹膜前腔内で膀胱頂部に接する6cm大の腫瘤を認めた．腫瘤の腹腔内への露出はなかった．膀胱とは剥離困難であったため，膀胱 …
NAID 130004706302

虫垂粘液腫所見を呈した虫垂子宮内膜症の1例

前田健一,種田靖久,田中千弘,長尾成敏,河合雅彦,國枝克行
日本臨床外科学会雑誌 75(3), 716-720, 2014
症例は45歳，女性．下血を主訴に前医を受診し，注腸検査にて盲腸部腫瘍を指摘され，当院へ紹介受診となった．CTにて虫垂内腔に液体貯留を認め，虫垂粘液腫と診断した．虫垂粘液腫所見を呈する疾患として，非腫瘍性貯留嚢胞だけでなく，虫垂粘液嚢胞腺腫や虫垂粘液嚢胞腺癌も鑑別すべきであり，術前画像検査で腫瘍性嚢胞が否定できなかった．そのため，患者の同意のもと，腹腔鏡下回盲部切除術（D2）を施行し，術後病理組織学 …
NAID 130004696555