モノカイン
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/02/20 11:16:02」(JST)
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A monokine is a type of cytokine[1] produced primarily by monocytes and macrophages.
Examples include interleukin 1 and tumor necrosis factor-alpha.
Other monokines include alpha and beta interferon, and colony stimulating factors.[2]
Contents
- 1 Functions
- 2 See also
- 3 References
- 4 External links
Functions[edit]
Monokines released from macrophages can attract neutrophils, via the process chemotaxis.
See also[edit]
References[edit]
- ^ Monokines at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ Julius M. Cruse; Robert Edwin Lewis (20 April 2009). Illustrated dictionary of immunology. CRC Press. pp. 208–. ISBN 978-0-8493-7987-1. Retrieved 24 April 2011.
External links[edit]
- Monokine at eMedicine Dictionary
Cell signaling: cytokines
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B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)
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UpToDate Contents
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English Journal
- Sulforaphane protects human chondrocytes against cell death induced by various stimuli.
- Facchini A, Stanic I, Cetrullo S, Borzi RM, Filardo G, Flamigni F.SourceDipartimento di Biochimica G. Moruzzi, University of Bologna, Bologna, Italy.
- Journal of cellular physiology.J Cell Physiol.2011 Jul;226(7):1771-9. doi: 10.1002/jcp.22506.
- Chondrocyte cell death can contribute to cartilage degeneration in articular diseases, such as osteoarthritis (OA). Sulforaphane (SFN), a natural compound derived from cruciferous aliment, is well known as an anti-carcinogen, but according to recent evidence it also shows cytoprotective effects on a
- PMID 21506109
- Serum chemokine receptor CXCR3 ligands are associated with progression, organ dysfunction and complications of chronic liver diseases.
- Tacke F, Zimmermann HW, Berres ML, Trautwein C, Wasmuth HE.SourceMedical Department III, University Hospital Aachen, Aachen, Germany.
- Liver international : official journal of the International Association for the Study of the Liver.Liver Int.2011 Jul;31(6):842-51. doi: 10.1111/j.1478-3231.2011.02504.x. Epub 2011 Mar 10.
- Background: Chemokines are chemotactic mediators that are implicated in liver diseases. In viral hepatitis and primary biliary cirrhosis, a predominant chemokine receptor expressed in the liver is CXCR3, suggesting that its specific ligands are important in the progression of chronic liver diseases
- PMID 21645215
Japanese Journal
- α-Viniferin Suppresses the Signal Transducer and Activation of Transcription-1 (STAT-1)–Inducible Inflammatory Genes in Interferon-γ–Stimulated Macrophages
- Chung Eun Yong,Roh Eunmiri,Kwak Jeong-Ah,Lee Heun-Sik,Lee Seung Ho,Lee Chong-Kil,Han Sang-Bae,Kim Youngsoo
- Journal of Pharmacological Sciences 112(4), 405-414, 2010
- … 10 μM dose-dependently inhibited IFN-γ–induced production of NO, IFN-γ–inducible protein-10 (IP-10), or the monokine induced by IFN-γ (MIG) in RAW 264.7 cells and also that of NO in primary macrophages-derived from C57BL/6 mice. …
- NAID 130000253380
- Serum chemokine profiles in patients with alopecia areata
- Kuwano Yoshihiro,Fujimoto Manabu,Watanabe Rei,Asashima Nobuko,Nakashima Hiroko,Ohno Hiroki,Yano Shoichiro,Yazawa Norihito,Okochi Hitoshi,Tamaki Kunihiko
- British Journal of Dermatology 157(3), 466-473, 2007-09
- … Methods: Serum samples from 85 patients with AA, 20 patients with atopic dermatitis, 20 patients with psoriasis vulgaris and 28 normal controls were examined by the cytometric bead array assay assessing monokine induced by interferon (IFN)-γ (MIG), RANTES, interleukin-8 (IL-8), IFN-inducible protein-10, monocyte chemoattractant protein-1, macrophage inflammatory protein (MIP)-1α, MIP-1β and eotaxin levels. …
- NAID 120001138122
Related Links
- Other monokines include alpha and beta interferon, and colony stimulating factors. ... [edit] Functions. Monokines released from macrophages can attract Neutrophils , via the process chemotaxis. ...
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★リンクテーブル★
[★]
- 英
- monokine, MK
- 関
- サイトカイン
[★]
- 同
- membrane cofactor protein, MCP