WordNet

the growing part of a long bone between the diaphysis and the epiphysis

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/11/16 16:40:33」(JST)

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The metaphysis is the narrow portion of a long bone between the epiphysis and the diaphysis.^[1] It contains the growth plate, the part of the bone that grows during childhood and as it grows, it ossifies near the diaphysis and the epiphyses.

The metaphysis may be divided anatomically into three components based on tissue content: a cartilaginous component (epiphyseal plate), a bony component (metaphysis) and a fibrous component surrounding the periphery of the plate. The growth plate synchronizes chondrogenesis with osteogenesis or interstitial cartilage growth with appositional bone growth at the same that it is growing in width, bearing load, and responding to local and systemic forces and factors.

During childhood, the growth plate contains the connecting cartilage enabling the bone to grow; at adulthood (between the ages of 18 to 25 years), the components of the growth plate stop growing altogether and completely ossify into solid bone.^[2] In an adult, the metaphysis functions to transfer loads from weight-bearing joint surfaces to the diaphysis.^[3]

Clinical significance

Because of their rich blood supply and vascular stasis, metaphyses of long bones are prone to hematogenous spread of osteomyelitis in children.^[4]

Metaphyseal tumors or lesions include osteosarcoma, chondrosarcoma, fibrosarcoma, osteoblastoma, enchondroma, fibrous dysplasia, simple bone cyst, aneurysmal bone cyst, non-ossifying fibroma, and osteoid osteoma.^[5]

One of the clinical signs of rickets that doctors look for is cupping and fraying at the metaphyses when seen on X-ray.

References

^ Dorland's Pocket Medical Dictionary, 27th edition
^ Visual dictionary of Merriam-Webster http://visual.merriam-webster.com/human-being/anatomy/skeleton/parts-long-bone.php
^ Encyclopædia Britannica, http://www.britannica.com/EBchecked/topic/377978/metaphysis
^ Luqmani, Raashid; Robb, James; Daniel, Porter; Benjamin, Joseph (2013). Orthopaedics, Trauma and Rheumatology (second ed.). Mosby. p. 96. ISBN 9780723436805.
^ "New Jersey Medical School, Pathology Department Introductory Course on Bone Tumours". Archived from the original on 2009-03-06. Retrieved 2009-03-12.

External links

Anatomy photo: Musculoskeletal/bone/structure0/structure2 - Comparative Organology at University of California, Davis - "Bone, structure (Gross, Low)"

UpToDate Contents

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1. 骨折のマネージメントの一般原則：小児における骨折のパターンおよび種類 general principles of fracture management fracture patterns and description in children
2. 骨折のマネージメントの一般原則：骨治癒および骨折について general principles of fracture management bone healing and fracture description
3. 児童虐待の整形外科的症状の鑑別診断 differential diagnosis of the orthopedic manifestations of child abuse
4. 先天梅毒：臨床的特徴および診断 congenital syphilis clinical features and diagnosis
5. 小児における血行性骨髄炎：疫学、病因、および微生物学 hematogenous osteomyelitis in children epidemiology pathogenesis and microbiology

English Journal

Temporal role of macrophages in cancellous bone healing.

Sandberg OH1, Tätting L2, Bernhardsson ME2, Aspenberg P3.
Bone.Bone.2017 Aug;101:129-133. doi: 10.1016/j.bone.2017.04.004. Epub 2017 Apr 14.
PMID 28414141

Effect of different mineralization processes on in vitro and in vivo bone regeneration and osteoblast-macrophage cross-talk in co-culture system using dual growth factor mediated non-mulberry silk fibroin grafted poly (Є-caprolactone) nanofibrous scaffold.

Bhattacharjee P1, Maiti TK2, Bhattacharya D3, Nandi SK4.
Colloids and surfaces. B, Biointerfaces.Colloids Surf B Biointerfaces.2017 Aug 1;156:270-281. doi: 10.1016/j.colsurfb.2017.05.043. Epub 2017 May 16.
PMID 28544959

Effects of Treadmill Exercise on Advanced Osteoarthritis Pain in Rats.

Allen J1, Imbert I1, Havelin J1, Henderson T2, Stevenson G1, Liaw L2, King T1.
Arthritis & rheumatology (Hoboken, N.J.).Arthritis Rheumatol.2017 Jul;69(7):1407-1417. doi: 10.1002/art.40101. Epub 2017 Jun 5.
PMID 28320059

Japanese Journal

Radial Shortening Osteotomy Using Volar Locking Plate for Kienböck's Disease

Denju Osada M.D.,Kazuya Tamai M.D.,Morimitsu Takai M.D.,Masahiro Kameda M.D.,Daisuke Tsuboyama M.D.,Yuji Yamaguchi.M.D.,Yutaka Nohara M.D.
Dokkyo journal of medical sciences 39(1), 9-15, 2012-03-25
… Purpose:The purpose of this study was to report the preliminary results for radial shortening osteotomyfollowed by volar locking plate fixation without post-operative immobilization for the treatment of Kienböck'sdisease.Methods:Ten consecutive patients with Kienböck's disease of stages III were treated by radial shorteningosteotomy at the metaphysis using a volar locking plate system. …
NAID 110009005502

乳児の骨髄炎型化膿性股関節炎に対して行った鏡視下治療の1例

伊藤亮太,関原力,相楽光利,小原周,渥美敬,扇谷浩文
昭和医学会雑誌 71(2), 181-186, 2011
症例は3か月女児，左下肢を動かさない事で近医受診後，精査目的で来院した．血液検査では軽度の炎症反応を認めた．単純股関節レントゲンでは左大腿骨近位骨幹端に骨吸収像と不整像を認めた．超音波で左股関節裂隙の開大を認め関節液の貯留を疑った．MRIでは左股関節内，周囲の軟部組織，骨幹端に周囲組織の炎症浸潤，骨髄浮腫または膿貯留を疑わせ，骨頭内の一部はモザイク状の所見を認め骨髄炎を疑わせた．関節穿刺液とdeb …
NAID 130001391021

Related Pictures

★リンクテーブル★

リンク元	「骨幹端」「metaphyseal」

「骨幹端」

Example of metaphyseal lines in lead poisoning case
Synonyms	Plumbism, colica pictorum, saturnism, Devon colic, painter's colic
	An X ray demonstrating the characteristic finding of lead poisoning in humans—dense metaphyseal lines.
Classification and external resources
Specialty	Toxicology
	[edit on Wikidata]

Metaphysis
	Structure of a long bone showing the metaphysis.
Details
Pronunciation	/mətˈæfɪsɪs/;
Identifiers
Latin	metaphysis
TA	A02.0.00.022
FMA	24014
	Anatomical terminology [edit on Wikidata]