- 関
- metaphysis
WordNet
- the growing part of a long bone between the diaphysis and the epiphysis
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/13 08:27:13」(JST)
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Not to be confused with metaphysics.
| Metaphysis |
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Structure of a long bone showing the metaphysis.
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| Details |
| Identifiers |
| Latin |
metaphysis |
| TA |
A02.0.00.022 |
| FMA |
24014 |
| Anatomical terminology
[edit on Wikidata]
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The metaphysis () is the wide portion of a long bone between the epiphysis and the narrow diaphysis.[1] It contains the growth plate, the part of the bone that grows during childhood and as it grows, it ossifies near the diaphysis and the epiphyses.
The growth plate may be divided anatomically into three components based on tissue content: a cartilaginous component (epiphyseal plate), a bony component (metaphysis) and a fibrous component surrounding the periphery of the plate. The growth plate synchronizes chondrogenesis with osteogenesis or interstitial cartilage growth with appositional bone growth at the same that it is growing in width, bearing load, and responding to local and systemic forces and factors.
During childhood, the growth plate contains the connecting cartilage enabling the bone to grow; at adulthood (between the ages of 18 to 25 years), the components of the growth plate stop growing altogether and completely ossify into solid bone.[2] In an adult, the metaphysis functions to transfer loads from weight-bearing joint surfaces to the diaphysis.[3]
Contents
- 1 Clinical significance
- 2 See also
- 3 References
- 4 External links
Clinical significance
Because of their rich blood supply and vascular stasis, metaphyses of long bones are prone to hematogenous spread of osteomyelitis in children.[4]
Metaphyseal tumors or lesions include osteosarcoma, chondrosarcoma, fibrosarcoma, osteoblastoma, enchondroma, fibrous dysplasia, simple bone cyst, aneurysmal bone cyst, non-ossifying fibroma, and osteoid osteoma.[5]
One of the clinical signs of rickets that doctors look for is cupping and fraying at the metaphyses when seen on X-ray.
See also
References
- ^ Dorland's Pocket Medical Dictionary, 27th edition
- ^ Visual dictionary of Merriam-Webster http://visual.merriam-webster.com/human-being/anatomy/skeleton/parts-long-bone.php
- ^ Encyclopedia Britanica, http://www.britannica.com/EBchecked/topic/377978/metaphysis
- ^ Luqmani, Raashid; Robb, James; Daniel, Porter; Benjamin, Joseph (2013). Orthopaedics, Trauma and Rheumatology (second ed.). Mosby. p. 96. ISBN 9780723436805.
- ^ "New Jersey Medical School, Pathology Department Introductory Course on Bone Tumours". Retrieved 2009-03-12.
External links
- Anatomy photo: Musculoskeletal/bone/structure0/structure2 - Comparative Organology at University of California, Davis - "Bone, structure (Gross, Low)"
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Bone and cartilage
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| Cartilage |
- perichondrium
- fibrocartilage callus
- metaphysis
- Cells
- Types
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| Bone |
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Ossification
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- intramembranous
- endochondral
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Cells
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- osteoblast
- osteoid
- osteocyte
- osteoclast
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Types
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Regions
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- subchondral bone
- epiphysis
- epiphyseal plate/metaphysis
- diaphysis
- Condyle
- Epicondyle
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Structure
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- Osteon
- Haversian canals
- Volkmann's canals
- connective tissue
- Sharpey's fibres
- enthesis
- lacunae
- canaliculi
- trabeculae
- medullary cavity
- bone marrow
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Shapes
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- long
- short
- flat
- irregular
- sesamoid
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UpToDate Contents
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English Journal
- Do Porous Tantalum Metaphyseal Cones Improve Outcomes in Revision Total Knee Arthroplasty?
- Bohl DD1, Brown NM1, McDowell MA1, Levine BR1, Sporer SM1, Paprosky WG1, Della Valle CJ1.
- The Journal of arthroplasty.J Arthroplasty.2018 Jan;33(1):171-177. doi: 10.1016/j.arth.2017.07.033. Epub 2017 Jul 28.
- PMID 28844630
- Management of pediatric open tibia fractures with supracutaneous locked plates.
- Radhakrishna VN1, Madhuri V.
- Journal of pediatric orthopedics. Part B.J Pediatr Orthop B.2018 Jan;27(1):13-16. doi: 10.1097/BPB.0000000000000425.
- PMID 28079741
- Proximal stress shielding is decreased with a short stem compared with a traditional-length stem in total shoulder arthroplasty.
- Denard PJ1, Noyes MP2, Walker JB3, Shishani Y4, Gobezie R4, Romeo AA5, Lederman E6.
- Journal of shoulder and elbow surgery.J Shoulder Elbow Surg.2018 Jan;27(1):53-58. doi: 10.1016/j.jse.2017.06.042. Epub 2017 Aug 31.
- PMID 28865965
Japanese Journal
- Cortical Bone Remodeling in Parosteal Osteosarcoma Mimicking Medullary Involvement: A Case with the Difficulty in Pre-Surgical Staging
- Shimoyama Tetsuo,Yamamoto Yasuhiro,Kuroda Makoto,Takakuwa Yasunari,Washimi Yuki,Ishimura Daisuke,Yamada Harumoto
- The Tohoku Journal of Experimental Medicine 233(3), 165-169, 2014
- … Parosteal osteosarcoma (POS) is a low-grade well-differentiated variant of osteosarcoma that affects the metaphyseal surface of a long bone. …
- NAID 130004460134
- Chiari Type I Malformation Caused by Craniometaphyseal Dysplasia
- Tanaka Masato,Arataki Shinya,Sugimoto Yoshihisa,Takigawa Tomoyuki,Tetsunaga Tomoko,Ozaki Toshifumi
- Acta Medica Okayama 67(6), 385-389, 2013-12
- … Craniometaphyseal dysplasia is a rare genetic condition characterized by progressive thickening of bones in the skull and metaphyseal abnormalities in the long bones. …
- NAID 120005353349
- Altered distribution of bone matrix proteins and defective bone mineralization in klotho-deficient mice
- Sasaki Muneteru,Hasegawa Tomoka,Yamada Tamaki,Hongo Hiromi,Luiz de Freitas Paulo Henrique,Suzuki Reiko,Yamamoto Tomomaya,Tabata Chihiro,Toyosawa Satoru,Yamamoto Tsuneyuki,Oda Kimimitsu,Li Minqi,Inoue Nobuo,Amizuka Norio
- Bone 57(1), 206-219, 2013-11
- … In kl/kl mice, however, MGP was seen around the cartilaginous cores of the metaphyseal trabeculae and in the periphery of some cells of the bone surface. …
- NAID 120005348968
Related Links
- ... in children. Metaphyseal tumors or lesions include osteosarcoma, chondrosarcoma, fibrosarcoma, osteoblastoma, enchondroma, fibrous dysplasia, simple bone cyst, aneurysmal bone cyst, non-ossifying fibroma, and osteoid osteoma.
- Jansen's metaphyseal chondrodysplasia or JMC is a disease that results from ligand-independent activation of the type 1 of the parathyroid hormone receptor ( PTHR1), due to one of three reported mutations (activating mutation).
★リンクテーブル★
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骨幹端異形成症、骨幹端異形成