WordNet

small room in which a monk or nun lives (同)cubicle
a device that delivers an electric current as the result of a chemical reaction (同)electric cell
a room where a prisoner is kept (同)jail cell, prison cell
(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
any small compartment; "the cells of a honeycomb"
a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
of or pertaining to large bone marrow cells

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1. 巨核球の生物学と血小板の産生 megakaryocyte biology and the production of platelets
2. 造血腫瘍の分類 classification of the hematopoietic neoplasms
3. 肝脾T細胞性リンパ腫の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of hepatosplenic t cell lymphoma
4. 慢性リンパ性白血病の臨床症状、病理学的特徴、診断、および鑑別診断 clinical presentation pathologic features diagnosis and differential diagnosis of chronic lymphocytic leukemia
5. 血小板産生因子の臨床応用 clinical applications of thrombopoietic growth factors

Megakaryocyte Polyploidization and Proplatelet Formation in Low-Attachment Conditions.

Schlinker AC1, Duncan MT1, DeLuca TA1, Whitehead DC1, Miller WM1.
Biochemical engineering journal.Biochem Eng J.2016 Jul 15;111:24-33.
In vitro-derived platelets (PLTs), which could provide an alternative source of PLTs for patient transfusions, are formed from polyploid megakaryocytes (MKs) that extend long cytoplasmic projections, termed proplatelets (proPLTs). In this study, we compared polyploidization and proPLT formation (PPF
PMID 27087780

Pyk2 and Megakaryocytes Regulate Osteoblast Differentiation and Migration Via Distinct and Overlapping Mechanisms.

Eleniste PP1, Patel V1, Posritong S1, Zero O1, Largura H1, Cheng YH2, Himes ER2, Hamilton M2, Baughman J2, Kacena MA2, Bruzzaniti A1.
Journal of cellular biochemistry.J Cell Biochem.2016 Jun;117(6):1396-406. doi: 10.1002/jcb.25430. Epub 2015 Dec 10.
Osteoblast differentiation and migration are necessary for bone formation during bone remodeling. Mice lacking the proline-rich tyrosine kinase Pyk2 (Pyk2-KO) have increased bone mass, in part due to increased osteoblast proliferation. Megakaryocytes (MKs), the platelet-producing cells, also promote
PMID 26552846

Zhu K1,2, Sun Y1, Miu A1, Yen M1, Liu B1, Zeng Q2, Mogilner A3, Zhao M1.
Journal of cellular physiology.J Cell Physiol.2016 Jun;231(6):1291-300. doi: 10.1002/jcp.25229. Epub 2015 Nov 24.
Cell fragments devoid of the nucleus and major organelles are found in physiology and pathology, for example platelets derived from megakaryocytes, and cell fragments from white blood cells and glioma cells. Platelets exhibit active chemotaxis. Fragments from white blood cells display chemotaxis, ph
PMID 26517849

佐藤博之,小宮佑介,星野茂
東京女子医科大学雑誌 83(E2), E608-E611, 2013-03-31
症例は78歳男性。持続する鼻出血を契機に血小板減少を指摘され当科初診。約1cmの左頸部リンパ節腫脹以外、基礎疾患を疑う所見は認めなかった。PAIgG高値および骨髄検査で巨核球系の過形成を認め、特発性血小板減少性紫斑病 (ITP) と診断。Prednisolone (PSL) 投与開始により血小板数は改善したが、減量に伴い再燃し、再増量を繰り返したため、治療開始11か月後よりeltrombopag …
NAID 110009575073

中嶋康博,白土基明,中嶋恵理子,油布祐二,藤岡絵里子,松島孝充,髙栁涼一
日本造血細胞移植学会雑誌 2(4), 112-115, 2013
症例は58歳男性。寛解導入不能の急性骨髄性白血病（FAB 分類：M7）に対し，強度減弱前処置を用い同種末梢血幹細胞移植を施行。移植後day 6 に発熱性好中球減少症を合併しドリペネムを投与開始。血液培養よりグラム陽性桿菌が検出され，Bacillus cereus（B. cereus）が疑われたため，バンコマイシンを追加した。Day 8 より，意識レベル低下，左片麻痺が出現，頭部MRI にて髄膜炎像 …
NAID 130003388486