基質タンパク質、基質タンパク、マトリックスタンパク質

WordNet

(geology) amass of fine-grained rock in which fossils, crystals, or gems are embedded
mold used in the production of phonograph records, type, or other relief surface
the body substance in which tissue cells are embedded (同)intercellular substance, ground_substance
(mathematics) a rectangular array of quantities or expressions set out by rows and columns; treated as a single element and manipulated according to rules
an enclosure within which something originates or develops (from the Latin for womb)
the formative tissue at the base of a nail
any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"

PrepTutorEJDIC

（複数形 matrices, ～・es）(発生・成長の)母体 / 鋳型・模型;(レコードの)原盤;(活字の)母型,字母 / (金属・化石・宝石などの含んだ)母岩・《古》子宮・基盤; (細胞)細胞間質; (地学)基質; (印)字母; 紙型; 鋳型; (鉱)母岩; (数)行列; (コンピュータ)マトリックス (入力導線と出力導線の回路網); (言)母型文（matrix sentence）
蛋白(たんばく)質
マトリクシング(4チャンネルに再生転換できる2チャンネルの録音方式)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/09/29 15:55:40」(JST)

wiki en

Viral matrix proteins are structural proteins linking the viral envelope with the virus core. They play a crucial role in virus assembly, and interact with the RNP complex as well as with the viral membrane. They are found in many enveloped viruses including paramyxoviruses (including pneumoviruses and morbilliviruses), orthomyxoviruses,^[1] herpesviruses, retroviruses and other groups.

An example is the M1 protein of the influenza virus, showing affinity to the glycoproteins inserted in the host cell membrane on one side and affinity for the RNP complex molecules on the other side, which allows formation at the membrane of a complex made of the viral ribonucleoprotein at the inner side indirectly connected to the viral glycoproteins protruding from the membrane. This assembly complex will now bud out of the cell as new mature viruses.

Viral matrix proteins, like many other viral proteins, can exert different functions during the course of the infection.

References

^ Battisti et al. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):13996-400.

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1. 変形性関節症のマネージメントへの研究的アプローチ investigational approaches to the management of osteoarthritis
2. 関節リウマチの病因 pathogenesis of rheumatoid arthritis
3. 研究用生物学的マーカーによる関節リウマチの診断および評価ま investigational biologic markers in the diagnosis and assessment of rheumatoid arthritis
4. 脳卒中のための血液バイオマーカー blood biomarkers for stroke
5. 尿路上皮（移行上皮）膀胱癌の検出のための尿中バイオマーカー urine biomarkers for the detection of urothelial transitional cell carcinoma of the bladder

English Journal

Development of a robust and sensitive LC-MS/MS method for the determination of adenine in plasma of different species and its application to in vivo studies.

Shi J, Liu HF, Wong JM, Huang RN, Jones E, Carlson TJ.SourceDepartment of Pharmacokinetics and Drug Metabolism, Amgen Inc., 1120 Veterans Blvd., South San Francisco, CA 94080, United States.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2011 Dec 5;56(4):778-84. Epub 2011 Jul 27.
A simple, robust, and sensitive liquid chromatography-tandem mass spectrometric (LC-MS/MS) method was developed for the measurement of endogenous adenine in mouse, rat, cynomolgus monkey, and human plasma. A "surrogate analyte" strategy was adopted by employing [(13)C(U)]-adenine as the surrogate an
PMID 21840665

Anti-angiogenic effect of Tanshinone IIA involves inhibition of matrix invasion and modification of MMP-2/TIMP-2 secretion in vascular endothelial cells.

Tsai MY, Yang RC, Wu HT, Pang JH, Huang ST.SourceDepartment of Chinese Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Taiwan, ROC.
Cancer letters.Cancer Lett.2011 Nov 28;310(2):198-206. Epub 2011 Jul 5.
Tanshinone IIA (Tan IIA) is one of the major lipophilic components of Salvia miltiorrhiza Bunge reported to exhibit anti-carcinogenic effect. In the present study, we further evaluated the anti-angiogenic effect of Tan IIA using the chorioallantoic membrane (CAM) in chicken embryos and human umbilic
PMID 21788102

Japanese Journal

Therapeutic Approaches to Vascular Protection in Ischemic Stroke

Yamashita Toru,Abe Koji
Acta Medica Okayama 65(4), 219-223, 2011-08
… Recent studies have indicated that matrix metalloproteinases (MMPs), especially MMP-9, play a critical role in blood brain barrier (BBB) disruption in the ischemic brain, leading to brain edema and HT. … In the ischemic brain, free radicals and exogenous tPA itself can trigger MMP-9 activation through several signaling pathways containing LDL receptor-related protein (LRP) and proteinase-activated receptor 1 (PAR1). …
NAID 120003290172

Detection of Antigen--Antibody Reaction Using Si Ring Optical Resonators Functionalized with an Immobilized Antibody-Binding Protein

Fukuyama Masataka,Nishida Mizue,Abe Yosuke [他],Amemiya Yoshiteru,Ikeda Takeshi,Kuroda Akio,Yokoyama Shin
Jpn J Appl Phys 50(4), 04DL07-04DL07-3, 2011-04-25
… Signal detection is carried out by the matrix of light-input and detection waveguides, which are respectively connected to laser diodes and photodetectors. … The unique point of our work is to use the silicon-binding protein (designated Si-tag), which binds to SiO2 surface, as an anchoring molecule to immobilize bioreceptor on the Si rings in an oriented manner. …
NAID 150000055663

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★リンクテーブル★

リンク元	「基質タンパク」「基質タンパク質」「マトリックスタンパク質」
拡張検索	「extracellular matrix protein」「enamel matrix protein」「cartilage oligomeric matrix protein」

「基質タンパク」

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Viral matrix protein
Identifiers
Symbol	Matrix
Pfam	PF00661
InterPro	IPR000982
Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary