WordNet

a light silver-white ductile bivalent metallic element; in pure form it burns with brilliant white flame; occurs naturally only in combination (as in magnesite and dolomite and carnallite and spinel and olivine) (同)Mg, atomic number 12

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/11/09 16:31:37」(JST)

Magnesium pidolate, the magnesium salt of pidolic acid (pyroglutamic acid), is a mineral supplement.

De Franceschi L, Bachir D, Galacteros F, et al. (2000). "Oral magnesium pidolate: effects of long-term administration in patients with sickle cell disease". Br. J. Haematol. 108 (2): 284–9. doi:10.1046/j.1365-2141.2000.01861.x. PMID 10691856.

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Design of an Inflammation-Sensitive Polyelectrolyte-Based Topical Drug Delivery System for Arthritis.

Bijukumar D1, Choonara YE1, Murugan K1, Choonara BF1, Kumar P1, du Toit LC1, Pillay V2.
AAPS PharmSciTech.AAPS PharmSciTech.2016 Oct;17(5):1075-85. doi: 10.1208/s12249-015-0434-6. Epub 2015 Oct 30.
The most successful treatment strategy for arthritis is intra-articular injections that are costly and have reduced patient compliance. The purpose of the current study was to develop an inflammation-sensitive system for topical drug administration. Multi-macromolecular alginate-hyaluronic acid-chit
PMID 26515798

Advantage of population pharmacokinetic method for evaluating the bioequivalence and accuracy of parameter estimation of pidotimod.

Huang J, Li M, Lv Y, Yang J, Xu L, Wang J, Chen J, Wang K, He Y, Zheng Q.
International journal of clinical pharmacology and therapeutics.Int J Clin Pharmacol Ther.2016 Sep;54(9):682-92. doi: 10.5414/CP202548.
OBJECTIVE: This study was aimed at exploring the accuracy of population pharmacokinetic method in evaluating the bioequivalence of pidotimod with sparse data profiles and whether this method is suitable for bioequivalence evaluation in special populations such as children with fewer samplings. Metho
PMID 27390049

Promising toxicological biomarkers for the diagnosis of liver injury types: Bile acid metabolic profiles and oxidative stress marker as screening tools in drug development.

Masubuchi N1, Nishiya T2, Imaoka M2, Mizumaki K3, Okazaki O4.
Chemico-biological interactions.Chem Biol Interact.2016 Aug 5;255:74-82. doi: 10.1016/j.cbi.2015.09.012. Epub 2015 Sep 11.
Promising biomarkers were identified in adult male Crl:CD (SD) rats for the screening of new chemical entities for their potential to cause liver injury. We examined the serum biochemistry, liver histopathology, and bile acid profiles by LC-MS/MS, and the mRNA expression of transporters and CYPs by
PMID 26365562

リンク元	「pyrrolidonecarboxylic acid」「ピドロ酸マグネシウム」
関連記事	「magnesium」

Magnesium pidolate
Systematic (IUPAC) name
	Magnesium 5-oxopyrrolidine-2-carboxylate
Clinical data
AHFS/Drugs.com	Consumer Drug Information
Identifiers
ATC code	A12CC08
PubChem	CID: 9838620
ChemSpider	8014340
Chemical data
Formula	C10H12MgN2O6
Molecular mass	280.517 g/mol
	SMILES [Mg+2].[O-]C(=O)C1NC(=O)CC1.[O-]C(=O)C1NC(=O)CC1 ;
	InChI InChI=1S/2C5H7NO3.Mg/c27-4-2-1-3(6-4)5(8)9;/h23H,1-2H2,(H,6,7)(H,8,9);/q;;+2/p-2 ; Key:JQAACYUZYRBHGG-UHFFFAOYSA-L ;
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