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a light silver-white ductile bivalent metallic element; in pure form it burns with brilliant white flame; occurs naturally only in combination (as in magnesite and dolomite and carnallite and spinel and olivine) (同)Mg, atomic number 12

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/22 03:35:44」(JST)

Magnesium orotate, the magnesium salt of orotic acid, is a mineral supplement.

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[Meta-analysis of clinical trials of cardiovascular effects of magnesium orotate].

Torshin IIu, Gromova OA, Kalacheva AG, Oshchepkova EV, Martynov AI.
Terapevticheskiĭ arkhiv.Ter Arkh.2015;87(6):88-97.
AIM: To make a meta-analysis of clinical trials of magnerot (magnesium orotate) used in cardiac patients.SUBJECTS AND METHODS: The meta-analysis covered the data of 19 randomized trials including a total of 603 patients treated with magnerot (a case group) and 587 receiving placebo (a control group)
PMID 26281202

Magnesium orotate elicits acute cardioprotection at reperfusion in isolated and in vivo rat hearts.

Mirica SN1, Duicu OM, Trancota SL, Fira-Mladinescu O, Angoulvant D, Muntean DM.
Canadian journal of physiology and pharmacology.Can J Physiol Pharmacol.2013 Feb;91(2):108-15. doi: 10.1139/cjpp-2012-0216. Epub 2013 Feb 19.
Orotic acid and its salts chronically administered have been shown to significantly improve cardiac function in pathological settings associated with ischemia-reperfusion (I/R) injury. The aim of our study was to investigate the effect of magnesium orotate (Mg-Or) administration at the onset of post
PMID 23458194

Gaĭsin IR1, Valeeva RM, Maksimov NI, Iskhakova AS, Khodyrev LA, Shilina LV.
Kardiologiia.Kardiologiia.2013;53(9):33-9.
We examined 150 pregnant women with essential hypertension (EHT), EHT and connective tissue dysplasia (CTD), and healthy. Presence of CTD aggravated clinical picture of EHT and was associated with pronounced cardialgic, neurological, asthenic, vertebrogenic, visceral, and other syndromes. The use of
PMID 24090384

関連記事	「orotate」「magnesium」

Magnesium orotate
Systematic (IUPAC) name
	magnesium 2,6-dioxo-3H-pyrimidine-4-carboxylate
Clinical data
AHFS/Drugs.com	Consumer Drug Information
Identifiers
CAS Number	27067-77-2
ATC code	A12CC09
PubChem	CID: 3036905
ChemSpider	2300801
Chemical data
Formula	C10H6MgN4O8
Molecular mass	334.482 g/mol
	SMILES [Mg+2].O=C([O-])\C1=C\C(=O)NC(=O)N1.[O-]C(=O)\C1=C\C(=O)NC(=O)N1 ;
	InChI InChI=1S/2C5H4N2O4.Mg/c28-3-1-2(4(9)10)6-5(11)7-3;/h21H,(H,9,10)(H2,6,7,8,11);/q;;+2/p-2 ; Key:QWLHYYKDLOVBNV-UHFFFAOYSA-L ;
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