lysyl-tRNA synthetase

リジルtRNA合成酵素、リジルtRNAシンテターゼ

関

lysine-tRNA ligase

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• 1. Clinical manifestations of dermatomyositis and polymyositis in adults
• 2. 成人における皮膚筋炎および多発性筋炎の初期治療 initial treatment of dermatomyositis and polymyositis in adults
• 3. ヘキソースリン酸側路およびグルタチオン代謝関連疾患 related disorders of the hexose monophosphate shunt and glutathione metabolism
• 4. 炎症性ミオパチーの病因 pathogenesis of inflammatory myopathies
• 5. 皮膚筋炎および多発性筋炎における間質性肺疾患：臨床症状および診断 interstitial lung disease in dermatomyositis and polymyositis clinical manifestations and diagnosis

English Journal

• Post-translational modification of HINT1 mediates activation of MITF transcriptional activity in human melanoma cells.

• Motzik A1, Amir E1, Erlich T1, Wang J2, Kim BG3, Han JM4,5, Kim JH6, Nechushtan H7, Guo M8, Razin E1, Tshori S9.
• Oncogene.Oncogene.2017 Apr 10. doi: 10.1038/onc.2017.81. [Epub ahead of print]
• PMID 28394346

• Expanding the genetic code of Mus musculus.

• Han S1, Yang A2, Lee S1, Lee HW3, Park CB1, Park HS2.
• Nature communications.Nat Commun.2017 Feb 21;8:14568. doi: 10.1038/ncomms14568.
• PMID 28220771

• Fragment-based methods for the discovery of inhibitors modulating lysyl-tRNA synthetase and laminin receptor interaction.

• Cho HY1, Kim S2, Jeon YH3.
• Methods (San Diego, Calif.).Methods.2017 Jan 15;113:56-63. doi: 10.1016/j.ymeth.2016.10.009. Epub 2016 Oct 24.
• PMID 27789335

Japanese Journal

• ISP-5-9 The Clinical Significance of Human Lysyl-tRNA Synthetase in Patients with Epithelial Ovarian Cancer(Group 5 Oncology 5,IS Poster,International Session)

• Lee Yoo-Young,Lee Jeong-Won,Cho Young Jae,Choi Jung-Joo,Do In-Gu,Song Sang Yong,Choi Chel Hun,Kim Tae-Joong,Kim Byoung-Gie,Bae Duk-Soo
• 日本産科婦人科學會雜誌 64(2), 901, 2012-02-01
• NAID 110009584048

• Two Crystal Structures of Lysyl-tRNA Synthetase from Bacillus stearothermophilus in Complex with Lysyladenylate-Like Compounds : Insights into the Irreversible Formation of the Enzyme-Bound Adenylate of L-Lysine Hydroxamate

• Sakurama Haruko,Takita Teisuke,Mikami Bunzo [他],ITOH Takafumi,YASUKAWA Kiyoshi,INOUYE Kuniyo
• The journal of biochemistry 145(5), 555-563, 2009-05-01
• NAID 10025588705

• Misacylation of Yeast Amber Suppressor tRNA^<Tyr> by E. coli Lysyl-tRNA Synthetase and Its Effective Repression by Genetic Engineering of the tRNA Sequence

• Fukunaga Jun-ichi,Yokogawa Takashi,Ohno Satoshi [他],NISHIKAWA Kazuya
• The journal of biochemistry 139(4), 689-696, 2006-04-01
• NAID 10018845541

Related Links

• KARS lysyl-tRNA synthetase [Homo sapiens (human)]

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA ...

• OMIM Entry - * 601421 - LYSYL-tRNA SYNTHETASE; KARS

TEXT Description The KARS gene encodes lysyl-tRNA synthetase, which catalyzes the aminoacylation of tRNA-lys in the cytoplasm and mitochondria.

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★リンクテーブル★

リンク元	「リジルtRNA合成酵素」「リジルtRNAシンテターゼ」「lysine-tRNA ligase」
関連記事	「synthetase」「tRNA」「tRNAs」

「リジルtRNA合成酵素」

　　[★]

英

lysyl-tRNA synthetase

関

リジンtRNAリガーゼ、リジルtRNAシンテターゼ

「リジルtRNAシンテターゼ」

　　[★]

英

lysyl-tRNA synthetase

関

リジルtRNA合成酵素

「lysine-tRNA ligase」

　　[★]

リジンtRNAリガーゼ

関

lysyl-tRNA synthetase

「synthetase」

　　[★]

• n.

• (ATPやNADを必要とする2分子連結酵素リガーゼの別名)シンテターゼ、シンセターゼ、連結酵素、合成酵素

関

ligase、synthase

「tRNA」

　　[★] トランスファーRNA, transfer RNA, 転位RNA

「tRNAs」

　　[★] トランスファーRNA transfer RNAs