リンパ球ホーミング受容体、リンパ球ホーミングレセプター
WordNet
- orienting or directing homeward or to a destination; "the homing instinct"; "a homing beacon"
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
- an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection (同)lymph cell
PrepTutorEJDIC
- 家に帰る;(ハトなどが)巣にもどる / (目的地への)誘導装置をもつ / 帰ること,帰還;(ハトなどの)帰巣性
- =sense organ / 受信装置
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/11/08 15:27:21」(JST)
[Wiki en表示]
Lymphocyte homing receptors are cell adhesion molecules[1] which target addressins.
Examples
Two well known examples are CD34 and GLYCAM-1.
References
- ^ Lymphocyte+homing+receptors at the US National Library of Medicine Medical Subject Headings (MeSH)
Membrane proteins: cell adhesion molecules
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Calcium-independent |
IgSF CAM |
- N-CAM (Myelin protein zero)
- ICAM (1, 5)
- VCAM-1
- PE-CAM
- L1-CAM
- Nectin (PVRL1, PVRL2, PVRL3)
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Integrins |
- LFA-1 (CD11a+CD18)
- Integrin alphaXbeta2 (CD11c+CD18)
- Macrophage-1 antigen (CD11b+CD18)
- VLA-4 (CD49d+CD29)
- Glycoprotein IIb/IIIa (ITGA2B+ITGB3)
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Calcium-dependent |
Cadherins |
Classical |
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Desmosomal |
- Desmoglein (DSG1, DSG2, DSG3, DSG4)
- Desmocollin (DSC1, DSC2, DSC3)
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Protocadherin |
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Unconventional/ungrouped |
- T-cadherin
- CDH4
- CDH5
- CDH6
- CDH8
- CDH11
- CDH12
- CDH15
- CDH16
- CDH17
- CDH9
- CDH10
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Selectins |
- E-selectin
- L-selectin
- P-selectin
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Other |
- Lymphocyte homing receptor: CD44
- L-selectin
- integrin (VLA-4, LFA-1)
- Carcinoembryonic antigen
- CD22
- CD24
- CD44
- CD146
- CD164
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- See also
- cell membrane protein disorders
B memb: cead, trns (1A, 1C, 1F, 2A, 3A1, 3A2-3, 3D), othr
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UpToDate Contents
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English Journal
- Orphan chemoattractant receptor GPR15 mediates dendritic epidermal T-cell recruitment to the skin.
- Lahl K1, Sweere J, Pan J, Butcher E.
- European journal of immunology.Eur J Immunol.2014 May 17. doi: 10.1002/eji.201444628. [Epub ahead of print]
- Homing of murine dendritic epidermal T cells (DETCs) from the thymus to the skin is regulated by specific trafficking receptors during late embryogenesis. Once in the epidermis, Vγ3δ1 TCR DETCs are maintained through self-renewal and participate in wound healing. GPR15 is an orphan G protein-linke
- PMID 24838826
- Detection and characterization of invasive circulating tumor cells derived from men with metastatic castration-resistant prostate cancer.
- Friedlander TW1, Ngo VT, Dong H, Premasekharan G, Weinberg V, Doty S, Zhao Q, Gilbert EG, Ryan CJ, Chen WT, Paris PL.
- International journal of cancer. Journal international du cancer.Int J Cancer.2014 May 15;134(10):2284-93. doi: 10.1002/ijc.28561. Epub 2014 Jan 2.
- The Vitatex cell-adhesion matrix (CAM) platform allows for isolation of invasive circulating tumor cells (iCTCs). Here we sought to determine the utility of prostate-specific membrane antigen (PSMA) as a metastatic castration-resistant prostate cancer (mCRPC) iCTC biomarker, to identify solitary cel
- PMID 24166007
- Conservation of the α4β7 lymphocyte homing receptor in HIV-infected patients with distinct transmission routes and disease progression profiles.
- Hait SH1, Darc M, Machado ES, Soares EA, Sprinz E, Soares MA.
- AIDS research and human retroviruses.AIDS Res Hum Retroviruses.2014 May;30(5):493-7. doi: 10.1089/AID.2013.0248. Epub 2014 Feb 7.
- The α4β7 is a lymphocyte homing receptor to the gut-associated lymphoid tissue (GALT). HIV-1 gp120 binds to α4β7 integrin through a mimetic tripeptide in V2 and ensures successful infection of GALT. In the present report, we investigated the presence of polymorphisms in the α4β7 cytoplasmic an
- PMID 24387749
Japanese Journal
- Regulatory Effect of Lysophosphatidic Acid on Lymphocyte Migration
- Tanikawa Takashi,Kurohane Kohta,Imai Yasuyuki
- Biological and Pharmaceutical Bulletin 33(2), 204-208, 2010
- … Another lipid mediator, sphingosine-1-phosphate (S1P), has been shown to influence lymphocyte recirculation by regulating lymphocyte egress from lymphoid organs. … We also demonstrated that LPA inhibits chemokine CCL21-induced lymphocyte migration. … The involvement of a receptor, LPA1, LPA2 or LPA3, in the inhibition of the CCL21-induced migration was confirmed with a synthetic agonist, oleyl thiophosphate. …
- NAID 130000156625
- 沢 禎彦
- 福岡歯科大学学会雑誌 33(4), 159-170, 2007-12-31
- 白血球接着因子は,血流から組織内に白血球が移住することに重要な役割を演じる。白血球の血管外遊走は,セレクチンと糖,化学遊走性因子とその受容体,またインテグリンと免疫グロブリンファミリー間の,3つの代表的な相互作用によって制御される。炎症初期において,E-/P-セレクチンとLewis^x,Lewis^aまたPSGL-1のレクチン活性による接着は,白血球の血管内皮上でのローリングをもたらす。L-セレク …
- NAID 110006532845
- 岩田 誠
- 腸内細菌学雑誌 = Journal of intestinal microbiology 21(4), 297-304, 2007-10-01
- 広い表面積で外界と接する腸管では,免疫細胞の配備が必須である.一般に,リンパ球の組織への配備は一定のルールに則って行われる.ナイーブT細胞は,リンパ節などの二次リンパ系器官には移入できるものの,非リンパ系組織には移入できない.二次リンパ系器官で抗原刺激を受けてエフェクター/メモリーT細胞となると,その二次リンパ系器官が所属する組織に選択的に移入(ホーミング)できるようになる.例えば,腸の二次リンパ …
- NAID 10019966283
Related Links
- Lymphocyte homing receptor. From Wikipedia, the free encyclopedia. Jump to: navigation, search. Lymphocyte homing receptors are cell adhesion molecules which target addressins.
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