WordNet

either of two saclike respiratory organs in the chest of vertebrates; serves to remove carbon dioxide and provide oxygen to the blood
coming to full development; becoming mature (同)ripening, maturement

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Transcriptionally-Active Human Papillomavirus is Consistently Retained in the Distant Metastases of Primary Oropharyngeal Carcinomas.

Mehrad M1, Zhao H, Gao G, Wang X, Lewis JS Jr.
Head and neck pathology.Head Neck Pathol.2014 Jun;8(2):157-63. doi: 10.1007/s12105-013-0509-1. Epub 2013 Nov 23.
High-risk human papillomavirus (HPV) is both causative and prognostic in the majority of oropharyngeal squamous cell carcinomas (OPSCCs). The aim of this study was to evaluate for transcriptionally-active HPV in matched primary OPSCCs and their distant metastases given the implications of HPV status
PMID 24271958

Ubiquitin-activating enzyme E1 inhibitor PYR41 attenuates angiotensin II-induced activation of dendritic cells via the IκBa/NF-κB and MKP1/ERK/STAT1 pathways.

Chen C1, Meng Y, Wang L, Wang HX, Tian C, Pang GD, Li HH, Du J.
Immunology.Immunology.2014 Jun;142(2):307-19. doi: 10.1111/imm.12255.
The activation of dendritic cells (DCs) is necessary to initiate immune responses. Angiotensin II (Ang II) can enhance the maturation and activation of DCs, but the mechanisms are still unclear. Ubiquitin-activating enzyme (E1/Uba1) is the common first step in ubiquitylation, which decides whether
PMID 24456201

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq.

Treutlein B1, Brownfield DG2, Wu AR3, Neff NF3, Mantalas GL3, Espinoza FH4, Desai TJ5, Krasnow MA4, Quake SR3.
Nature.Nature.2014 May 15;509(7500):371-5. doi: 10.1038/nature13173. Epub 2014 Apr 13.
The mammalian lung is a highly branched network in which the distal regions of the bronchial tree transform during development into a densely packed honeycomb of alveolar air sacs that mediate gas exchange. Although this transformation has been studied by marker expression analysis and fate-mapping,
PMID 24739965

Involvement of Choline Transporter-Like Proteins, CTL1 and CTL2, in Glucocorticoid-Induced Acceleration of Phosphatidylcholine Synthesis via Increased Choline Uptake

Nakamura Toshimichi,Fujiwara Ryohei,Ishiguro Naoki,Oyabu Masanobu,Nakanishi Takeo,Shirasaka Yoshiyuki,Maeda Tomoji,Tamai Ikumi
Biological & Pharmaceutical Bulletin 33(4), 691-696, 2010
… Phosphatidylcholine (PC) production is accelerated by glucocorticoid, such as dexamethasone (DEX), which enhances fetal lung maturation, promotes differentiation of alveolar type II (ATII) cells, and increases production of both lipid and protein components of lung surfactant. …
NAID 40017031070