ロベンザリット
- 関
- lobenzarit disodium
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/21 12:53:13」(JST)
[Wiki en表示]
Lobenzarit
|
Systematic (IUPAC) name |
2-[(2-Carboxyphenyl)amino]-4-chlorobenzoic acid
|
Clinical data |
AHFS/Drugs.com |
International Drug Names |
Legal status |
|
Routes of
administration |
Oral |
Identifiers |
CAS Number |
63329-53-3 Y |
ATC code |
None |
PubChem |
CID: 3946 |
ChemSpider |
3809 N |
UNII |
915EE91P39 Y |
Chemical data |
Formula |
C14H10ClNO4 |
Molecular mass |
291.68 g/mol |
SMILES
-
C1=CC=C(C(=C1)C(=O)O)NC2=C(C=CC(=C2)Cl)C(=O)O
|
InChI
-
InChI=1S/C14H10ClNO4/c15-8-5-6-10(14(19)20)12(7-8)16-11-4-2-1-3-9(11)13(17)18/h1-7,16H,(H,17,18)(H,19,20) N
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Key:UGDPYGKWIHHBMB-UHFFFAOYSA-N N
|
NY (what is this?) (verify) |
Lobenzarit (INN) is a drug used in the treatment of arthritis. It is an immunomodulator.[1]
References
- ^ Abe T (April 1981). "[Development and clinical use of chemical immunomodulators]". Nippon Rinsho (in Japanese) 39 (4): 1893–901. PMID 6796722.
English Journal
- Corrigendum: Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis.
- Evans GL, Gamage SA, Bulloch EM, Baker EN, Denny WA, Lott JS.
- Chembiochem : a European journal of chemical biology.Chembiochem.2015 Mar 23;16(5):706. doi: 10.1002/cbic.201500098. Epub 2015 Mar 11.
- PMID 26177917
- Repurposing the chemical scaffold of the anti-arthritic drug Lobenzarit to target tryptophan biosynthesis in Mycobacterium tuberculosis.
- Evans GL1, Gamage SA, Bulloch EM, Baker EN, Denny WA, Lott JS.
- Chembiochem : a European journal of chemical biology.Chembiochem.2014 Apr 14;15(6):852-64. doi: 10.1002/cbic.201300628. Epub 2014 Mar 12.
- PMID 24623674
- Identifying mechanism-of-action targets for drugs and probes.
- Gregori-Puigjané E1, Setola V, Hert J, Crews BA, Irwin JJ, Lounkine E, Marnett L, Roth BL, Shoichet BK.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2012 Jul 10;109(28):11178-83. doi: 10.1073/pnas.1204524109. Epub 2012 Jun 18.
- PMID 22711801
Japanese Journal
- Study of the Critical Points in Lobenzarit Disodium Hydrophilic Matrices for Controlled Drug Delivery
- Application of a New Mathematical Method for the Estimation of the Mean Surface Area to Calculate the Percolation Threshold of Lobenzarit Dissodium Salt in Controlled Release Matrices
Related Links
- Lobenzarit (INN) is a drug used in the treatment of arthritis. It is an immunomodulator. [edit] References. ^ Abe T (April 1981). "[Development and clinical use of chemical immunomodulators]" (in Japanese). Nippon Rinsho 39 (4 ): 1893–901.
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