WordNet

speak with a lisp
a speech defect that involves pronouncing `s like voiceless `th and `z like voiced `th
hormone secreted by the isles of Langerhans in the pancreas; regulates storage of glycogen in the liver and accelerates oxidation of sugar in cells

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1. 2型糖尿病におけるインスリン療法 insulin therapy in type 2 diabetes mellitus
2. 糖尿病におけるインスリン療法の一般原則 general principles of insulin therapy in diabetes mellitus
3. 成人の1型糖尿病における血糖値マネージメント management of blood glucose in adults with type 1 diabetes mellitus
4. 糖尿病症例解説3：1型糖尿病患者における低血糖 interactive diabetes case 3 hypoglycemia in a patient with type 1 diabetes
5. 糖尿病に対するインスリン療法に関する問題についての症例 cases illustrating problems with insulin therapy for diabetes mellitus

Clinical application of the different cross-reactivities of anti-insulin antibodies to insulin lispro to evaluate endogenous insulin secretion.

Yoshida R, Ohkubo K, Akehi Y, Harada S, Shinohara K, Kawashima H, Ono J, Matsunaga A.SourceDepartment of Laboratory Medicine, Faculty of Medicine, Fukuoka University, Japan; Department of Endocrinology and Diabetes, Faculty of Medicine, Fukuoka University, Japan.
Clinica chimica acta; international journal of clinical chemistry.Clin Chim Acta.2013 Jan 16;415:250-4. doi: 10.1016/j.cca.2012.10.062. Epub 2012 Nov 13.
BACKGROUND: Insulin analogs are often used to treat patients with diabetes. We evaluated the cross-reactivities of anti-insulin antibodies in two insulin immunoassay kits (Architect and ECLusys) against recombinant human insulin and insulin analogs, and measured insulin concentrations in the serum o
PMID 23159841

Analysis of the local dynamics of human insulin and a rapid-acting insulin analog by hydrogen/deuterium exchange mass spectrometry.

Nakazawa S, Ahn J, Hashii N, Hirose K, Kawasaki N.SourceGraduate School of Life Science, Hokkaido University, Kita 12-Nishi 6, Kita-ku, Sapporo 060-0812, Japan; Division of Biological Chemistry and Biologicals, National Institute of Health Sciences, 1-18-1 Kami-yoga, Setagaya-ku, Tokyo 158-8501, Japan. Electronic address: nakazawa@pharm.hokuai.ac.jp.
Biochimica et biophysica acta.Biochim Biophys Acta.2012 Dec 7. pii: S1570-9639(12)00269-5. doi: 10.1016/j.bbapap.2012.11.012. [Epub ahead of print]
Human insulin and insulin lispro (lispro), a rapid-acting insulin analog, have identical primary structures, except for the transposition of a pair of amino acids. This mutation results in alterations in their higher order structures, with lispro dissociating more easily than human insulin. In our p
PMID 23220415