WordNet
- respiratory disease characterized by inflammation of the lung parenchyma (excluding the bronchi) with congestion caused by viruses or bacteria or irritants
PrepTutorEJDIC
- 肺炎
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/01/01 19:14:33」(JST)
[Wiki en表示]
| Lipid pneumonia |
| Classification and external resources |
| ICD-9-CM |
516.8 |
| OMIM |
215030 |
| MeSH |
D011017 |
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[edit on Wikidata]
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Lipid pneumonia or lipoid pneumonia is a specific form of lung inflammation (pneumonia) that develops when lipids enter the bronchial tree. The disorder is sometimes called cholesterol pneumonia in cases where that lipid is a factor.[1]
Contents
- 1 History
- 2 Clinical manifestations
- 3 Causes
- 4 Appearance
- 5 Treatment
- 6 Prognosis
- 7 References
- 8 Further reading
- 9 External links
History
Laughlen first described lipid pneumonia in 1925 with infants that inhaled oil droplets.[2] It is a condition that has been seen as an occupational risk for commercial diving operations but documented cases are rare.[2]
Clinical manifestations
The pneumonia presents as a foreign body reaction causing cough, dyspnoea, and often fever. Haemoptysis has also been reported.[3]
Causes
Sources of such lipids could be either exogenous or endogenous.[4]
Exogenous: from outside the body. For example, inhaled nose drops with an oil base, or accidental inhalation of cosmetic oil. Amiodarone is an anti-arrythmic known to cause this condition. Oil pulling has also been shown to be a cause.[5] At risk populations include the elderly, developmentally delayed or persons with gastroesophageal reflux. Switching to water-soluble alternatives may be helpful in some situations.[3]
Endogenous: from the body itself, for example, when an airway is obstructed, it is often the case that distal to the obstruction, lipid-laden macrophages (foamy macrophages) and giant cells fill the lumen of the disconnected airspace.[6]
Appearance
The gross appearance of a lipid pneumonia is that in which there is an ill-defined, pale yellow area on the lung. This yellow appearance explains the colloquial term "golden" pneumonia.
At the microscopic scale foamy macrophages and giant cells are seen in the airways, and the inflammatory response is visible in the parenchyma.
Treatment
Treatment is with corticosteroids and possibly intravenous immunoglobulins.
Prognosis
Endogenous lipoid pneumonia and non-specific interstitial pneumonitis has been seen prior to the development of pulmonary alveolar proteinosis in a child.[6]
References
- ^ Pelz L, Hobusch D, Erfurth F, Richter K (1972). "[Familial cholesterol pneumonia]". Helv Paediatr Acta. 27 (4): 371–9. PMID 4644274.
- ^ a b Kizer KW, Golden JA (November 1987). "Lipoid pneumonitis in a commercial abalone diver". Undersea Biomedical Research. 14 (6): 545–52. PMID 3686744. Retrieved 2013-04-02.
- ^ a b Moe Bell, Marvin (2015). "Lipoid pneumonia: An unusual and preventable illness in elderly patients". Canadian Family Physician. 61 (9): 775–777. PMC 4569110. PMID 26371101.
- ^ "Pulmonary Pathology". Retrieved 21 November 2008.
- ^ Kim JY, Jung JW, Choi JC, Shin JW, Park IW, Choi BW (February 2014). "Recurrent lipoid pneumonia associated with oil pulling". The International Journal of Tuberculosis and Lung Disease. 18 (2): 251–2. doi:10.5588/ijtld.13.0852. PMID 24429325.
- ^ a b Antoon JW, Hernandez ML, Roehrs PA, Noah TL, Leigh MW, Byerley JS (2014). "Endogenous lipoid pneumonia preceding diagnosis of pulmonary alveolar proteinosis". Clin Respir J. doi:10.1111/crj.12197. PMID 25103284.
Further reading
- Spickard, Anderson; Hirschmann, JV (Mar 28, 1994). "Exogenous Lipoid Pneumonia". Archives of Internal Medicine. 154 (6): 686–92. doi:10.1001/archinte.1994.00420060122013. PMID 8129503.
- Betancourt, SL; Martinez-Jimenez, S; Rossi, SE; Truong, MT; Carrillo, J; Erasmus, JJ (January 2010). "Lipoid pneumonia: spectrum of clinical and radiologic manifestations.". AJR. American journal of roentgenology. 194 (1): 103–9. doi:10.2214/ajr.09.3040. PMID 20028911.
External links
- Gross pathology specimen from the University of Utah
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Diseases of the respiratory system (J, 460–519)
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Upper RT
(including URTIs,
common cold) |
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Head
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- sinuses
- Sinusitis
- nose
- Rhinitis
- Vasomotor rhinitis
- Atrophic rhinitis
- Hay fever
- Nasal polyp
- Rhinorrhea
- nasal septum
- Nasal septum deviation
- Nasal septum perforation
- Nasal septal hematoma
- tonsil
- Tonsillitis
- Adenoid hypertrophy
- Peritonsillar abscess
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Neck
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- pharynx
- Pharyngitis
- Strep throat
- Laryngopharyngeal reflux (LPR)
- Retropharyngeal abscess
- larynx
- Croup
- Laryngomalacia
- Laryngeal cyst
- Laryngitis
- Laryngopharyngeal reflux (LPR)
- Laryngospasm
- vocal folds
- Laryngopharyngeal reflux (LPR)
- Vocal fold nodule
- Vocal cord paresis
- Vocal cord dysfunction
- epiglottis
- Epiglottitis
- trachea
- Tracheitis
- Tracheal stenosis
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Lower RT/lung disease
(including LRTIs) |
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Bronchial/
obstructive
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- acute
- Acute bronchitis
- chronic
- COPD
- Chronic bronchitis
- Acute exacerbations of chronic bronchitis
- Acute exacerbation of COPD
- Emphysema)
- Asthma (Status asthmaticus
- Aspirin-induced
- Exercise-induced
- Bronchiectasis
- unspecified
- Bronchitis
- Bronchiolitis
- Bronchiolitis obliterans
- Diffuse panbronchiolitis
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|
Interstitial/
restrictive
(fibrosis) |
External agents/
occupational
lung disease |
- Pneumoconiosis
- Asbestosis
- Baritosis
- Bauxite fibrosis
- Berylliosis
- Caplan's syndrome
- Chalicosis
- Coalworker's pneumoconiosis
- Siderosis
- Silicosis
- Talcosis
- Byssinosis
- Hypersensitivity pneumonitis
- Bagassosis
- Bird fancier's lung
- Farmer's lung
- Lycoperdonosis
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Other
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- ARDS
- Pulmonary edema
- Löffler's syndrome/Eosinophilic pneumonia
- Respiratory hypersensitivity
- Allergic bronchopulmonary aspergillosis
- Hamman-Rich syndrome
- Idiopathic pulmonary fibrosis
- Sarcoidosis
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Obstructive or
restrictive
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Pneumonia/
pneumonitis
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By pathogen
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- Viral
- Bacterial
- Atypical bacterial
- Mycoplasma
- Legionnaires' disease
- Chlamydiae
- Fungal
- Parasitic
- noninfectious
- Chemical/Mendelson's syndrome
- Aspiration/Lipid
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By vector/route
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- Community-acquired
- Healthcare-associated
- Hospital-acquired
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By distribution
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IIP
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Other
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- Atelectasis
- circulatory
- Pulmonary hypertension
- Pulmonary embolism
- Lung abscess
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Pleural cavity/
mediastinum |
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Pleural disease
|
- Pneumothorax/Hemopneumothorax
- Pleural effusion
- Hemothorax
- Hydrothorax
- Chylothorax
- Empyema/pyothorax
- Malignant
- Fibrothorax
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Mediastinal disease
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- Mediastinitis
- Mediastinal emphysema
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| Other/general |
- Respiratory failure
- Influenza
- SARS
- Idiopathic pulmonary haemosiderosis
- Pulmonary alveolar proteinosis
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Pneumonia
|
|
| Infectious pneumonias |
- Bacterial pneumonia
- Viral pneumonia
- Fungal pneumonia
- Parasitic pneumonia
- Atypical pneumonia
- Community-acquired pneumonia
- Healthcare-associated pneumonia
- Hospital-acquired pneumonia
- Ventilator-associated pneumonia
- Severe acute respiratory syndrome
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Pneumonias caused by
infectious or noninfectious agents |
- Aspiration pneumonia
- Lipid pneumonia
- Eosinophilic pneumonia
- Bronchiolitis obliterans organizing pneumonia
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| Noninfectious pneumonia |
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UpToDate Contents
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English Journal
- Prenatal exposure to p,p'-DDE and p,p'-DDT in relation to lower respiratory tract infections in boys from a highly exposed area of Mexico.
- Cupul-Uicab LA1, Terrazas-Medina EA2, Hernández-Ávila M2, Longnecker MP3.
- Environmental research.Environ Res.2014 Jul;132:19-23. doi: 10.1016/j.envres.2014.03.017. Epub 2014 Apr 16.
- BACKGROUND: Prenatal exposure to 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE), the major breakdown product of DDT, has been associated with recurrent lower respiratory tract infections (LRTIs) in infants. However, epidemiological investigations are limited.OBJECTIVE: To assess the associa
- PMID 24742723
- The Spectrum of Lung Disease due to Chronic Occult Aspiration.
- Cardasis JJ1, MacMahon H, Husain AN.
- Annals of the American Thoracic Society.Ann Am Thorac Soc.2014 Jun 20. [Epub ahead of print]
- Introduction: Chronic aspiration of small volumes of oral and gastric contents can lead to lung disease. This process is less familiar than the acute aspiration syndromes, which can create confusion in terminology as well as with radiologic and pathologic definitions. Objectives: In this study we an
- PMID 24950025
Japanese Journal
- ごま油によるリポイド肺炎に合併した,難治性肺Mycobacterium fortuitum感染症の1例
- 乳糜胸を伴うリンパ脈管筋腫症に合併した外因性リポイド肺炎の1例
- 症例 胃切除後,腸閉塞を繰り返した患者に認められた特異なリポイド肺炎の1例
- 日本呼吸器学会誌 = Annals of the Japanese Respiratory Society 5(1), 46-51, 2016-01-10
- NAID 40020711026
Related Links
- The constellation of chronic cough, dyspnea, and hemoptysis can include a broad range of differential diagnoses. Although uncommon, exogenous lipoid pneumonia (ELP) should be considered when patients present with ...
- Lipoid Pneumonia cases have been discussed in this article. Get to know more about how laxatives can increase the incidence of lipoid pneumonia. ... Lipoid pneumonia is also called pneumonitis and it results from the aspiration of ...
★リンクテーブル★
[★]
リ・イド肺炎
- 関
- lipoid pneumonia
[★]
- 英
- lipoid pneumonia、lipid pneumonia
[★]
リポ、脂肪
- 関
- adipose、fat、lipid
[★]