若年性メースマン角膜上皮変性症、若年性Meesmann角膜上皮変性症
- 関
- Meesmann corneal epithelial dystrophy
WordNet
- of or relating to or characteristic of or appropriate for children or young people; "juvenile diabetes"; "juvenile fashions"
- a young person, not fully developed (同)juvenile person
- any degenerative disorder resulting from inadequate or faulty nutrition
- the transparent dome-shaped anterior portion of the outer covering of the eye; it covers the iris and pupil and is continuous with the sclera
- of or belonging to the epithelium; "epithelial layer"
PrepTutorEJDIC
- 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
- 少年少女向きの / 少年の,少女の,若い / 子供じみた,未熟な / 少年,少女 / 子役の俳優
- 栄養障害 / 筋萎縮症,筋ジストロフィー(筋肉の退化・萎縮・運動障害などが起こる病気)
- (眼球の)角膜
UpToDate Contents
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English Journal
- Severe Meesmann's epithelial corneal dystrophy phenotype due to a missense mutation in the helix-initiation motif of keratin 12.
- Hassan H, Thaung C, Ebenezer ND, Larkin G, Hardcastle AJ, Tuft SJ.SourceMoorfields Eye Hospital NHS Foundation Trust, London, UK.
- Eye (London, England).Eye (Lond).2013 Mar;27(3):367-73. doi: 10.1038/eye.2012.261. Epub 2012 Dec 7.
- PURPOSE: To describe a severe phenotype of Meesmann's epithelial corneal dystrophy (MECD) and to determine the underlying molecular cause.METHODS: We identified a 30-member family affected by MECD and examined 11 of the 14 affected individuals. Excised corneal tissue from one affected individual was
- PMID 23222558
- Allele-specific siRNA silencing for the common keratin 12 founder mutation in Meesmann epithelial corneal dystrophy.
- Allen EH, Atkinson SD, Liao H, Moore JE, Leslie Pedrioli DM, Smith FJ, McLean WH, Moore CB.SourceSchool of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland BT52 1SA, United Kingdom.
- Investigative ophthalmology & visual science.Invest Ophthalmol Vis Sci.2013 Jan 17;54(1):494-502. doi: 10.1167/iovs.12-10528.
- PURPOSE: To identify an allele-specific short interfering RNA (siRNA), against the common KRT12 mutation Arg135Thr in Meesmann epithelial corneal dystrophy (MECD) as a personalized approach to treatment.METHODS: siRNAs against the K12 Arg135Thr mutation were evaluated using a dual luciferase reporte
- PMID 23233254
- Development of allele-specific therapeutic siRNA in Meesmann epithelial corneal dystrophy.
- Liao H, Irvine AD, Macewen CJ, Weed KH, Porter L, Corden LD, Gibson AB, Moore JE, Smith FJ, McLean WH, Moore CB.SourceDivision of Molecular Medicine, Colleges of Life Sciences and Medicine, Dentistry & Nursing, University of Dundee, Dundee, Scotland.
- PloS one.PLoS One.2011;6(12):e28582. doi: 10.1371/journal.pone.0028582. Epub 2011 Dec 12.
- BACKGROUND: Meesmann epithelial corneal dystrophy (MECD) is an inherited eye disorder caused by dominant-negative mutations in either keratins K3 or K12, leading to mechanical fragility of the anterior corneal epithelium, the outermost covering of the eye. Typically, patients suffer from lifelong ir
- PMID 22174841
Related Links
- Meesmann corneal dystrophy Meesmann corneal dystrophy An autosomal dominant condition OMIM:122100 characterised by fragility of the anterior corneal epithelium due to the presence of innumerable microcysts. Patients are ...
- Meesmann corneal dystrophy Meesmann corneal dystrophy An autosomal dominant condition OMIM:122100 characterised by fragility of the anterior corneal epithelium due to the presence of innumerable microcysts. Patients are ...
★リンクテーブル★
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メースマン角膜上皮変性症、Meesmann角膜上皮変性症
- 関
- juvenile epithelial of Meesmann corneal dystrophy
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- 英
- juvenile epithelial of Meesmann corneal dystrophy
- 関
- メースマン角膜上皮変性症、若年性Meesmann角膜上皮変性症
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- 英
- juvenile epithelial of Meesmann corneal dystrophy
- 関
- 若年性メースマン角膜上皮変性症
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- (医)栄養失調、栄養失調症。(医)異栄養、異栄養症、ジフトロフィー
- 栄養障害。細胞や組織の物質代謝障害によって変性・萎縮などの起こること。
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- 関
- juvenilis、young
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- 関
- epidermal、epithelia、epithelium
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- 関
- cornea
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