メースマン角膜上皮変性症、Meesmann角膜上皮変性症
- 関
- juvenile epithelial of Meesmann corneal dystrophy
WordNet
- any degenerative disorder resulting from inadequate or faulty nutrition
- the transparent dome-shaped anterior portion of the outer covering of the eye; it covers the iris and pupil and is continuous with the sclera
- of or belonging to the epithelium; "epithelial layer"
- of or related to the cornea
PrepTutorEJDIC
- 栄養障害 / 筋萎縮症,筋ジストロフィー(筋肉の退化・萎縮・運動障害などが起こる病気)
- (眼球の)角膜
- 角膜の
UpToDate Contents
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English Journal
- siRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy.
- Courtney DG1, Atkinson SD1, Allen EH1, Moore JE1, Walsh CP1, Pedrioli DM2, MacEwen CJ3, Pellegrini G4, Maurizi E5, Serafini C4, Fantacci M4, Liao H2, Irvine AD6, McLean WH2, Moore CB7.
- Investigative ophthalmology & visual science.Invest Ophthalmol Vis Sci.2014 May 6;55(5):3352-60. doi: 10.1167/iovs.13-12957.
- PURPOSE: The aim of this study is to further assess our previously reported keratin 12 (K12)-Leu132Pro specific siRNA in silencing the mutant allele in Meesmann's Epithelial Corneal Dystrophy (MECD) in experimental systems more akin to the in vivo situation through simultaneous expression of both wi
- PMID 24801514
- KRT12 mutations and in vivo confocal microscopy in two Japanese families with Meesmann corneal dystrophy.
- Ogasawara M1, Matsumoto Y2, Hayashi T3, Ohno K3, Yamada H4, Kawakita T2, Dogru M5, Shimazaki J6, Tsubota K2, Tsuneoka H3.
- American journal of ophthalmology.Am J Ophthalmol.2014 Jan;157(1):93-102.e1. doi: 10.1016/j.ajo.2013.08.008. Epub 2013 Oct 5.
- PURPOSE: To identify genetic mutations and study the corneal epithelium in Japanese patients with Meesmann corneal dystrophy.DESIGN: Laboratory investigation and prospective observational case series.METHODS: Slit-lamp biomicroscopy with fluorescein vital staining and in vivo confocal microscopy wer
- PMID 24099278
- Autosomal-dominant Meesmann epithelial corneal dystrophy without an exon mutation in the keratin-3 or keratin-12 gene in a Chinese family.
- Cao W1, Yan M, Hao Q, Wang S, Wu L, Liu Q, Li M, Biddle FG, Wu W.
- The Journal of international medical research.J Int Med Res.2013 Apr;41(2):511-8. doi: 10.1177/0300060513477306. Epub 2013 Mar 12.
- Meesmann epithelial corneal dystrophy (MECD) is a dominantly inherited disorder, characterized by fragility of the anterior corneal epithelium and formation of intraepithelial microcysts. It has been described in a number of different ancestral groups. To date, all reported cases of MECD have been a
- PMID 23569037
Japanese Journal
- Isolation and chromosomal localization of a cornea-specific human keratin 12 gene and detection of four mutations in Meesmann corneal epithelial dystrophy
Related Links
- Meesmann corneal dystrophy is a rare genetic condition affecting the epithelial membrane of the cornea. A slit-lamp examination of the cornea shows diffuse clusters of tiny round cysts in the epithelial membrane. Overtime these cysts can ...
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若年性メースマン角膜上皮変性症、若年性Meesmann角膜上皮変性症
- 関
- Meesmann corneal epithelial dystrophy
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- 英
- Meesmann corneal epithelial dystrophy
- 関
- 若年性メースマン角膜上皮変性症、Meesmann角膜上皮変性症
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- 英
- Meesmann corneal epithelial dystrophy
- 関
- メースマン角膜上皮変性症
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- (医)栄養失調、栄養失調症。(医)異栄養、異栄養症、ジフトロフィー
- 栄養障害。細胞や組織の物質代謝障害によって変性・萎縮などの起こること。
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- 関
- epidermal、epithelia、epithelium
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- 関
- cornea
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