WordNet

a complex consisting of an organic base in association with hydrogen chloride

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1. 成人における機能性胃腸症 functional dyspepsia in adults
2. 悪性腫瘍関連胃不全麻痺：病態生理およびマネージメント malignancy associated gastroparesis pathophysiology and management

English Journal

QbD-enabled systematic development of gastroretentive multiple-unit microballoons of itopride hydrochloride.

Bansal S1, Beg S2, Asthana A3, Garg B2, Asthana GS3, Kapil R2, Singh B2,4.
Drug delivery.Drug Deliv.2016 Feb;23(2):437-451. Epub 2014 May 28.
The objectives of present studies were to develop the systematically optimized multiple-unit gastroretentive microballoons, i.e. hollow microspheres of itopride hydrochloride (ITH) employing quality by design (QbD)-based approach. Initially, the patient-centric QTPP and CQAs were earmarked, and prel
PMID 24865292

Acotiamide Hydrochloride, a Therapeutic Agent for Functional Dyspepsia, Enhances Acetylcholine-induced Contraction via Inhibition of Acetylcholinesterase Activity in Circular Muscle Strips of Guinea Pig Stomach.

Ito K1, Kawachi M1, Matsunaga Y1, Hori Y1, Ozaki T1, Nagahama K1, Hirayama M1, Kawabata Y1, Shiraishi Y1, Takei M1, Tanaka T1.
Drug research.Drug Res (Stuttg).2015 Sep 29. [Epub ahead of print]
Acotiamide is a first-in-class prokinetic drug approved in Japan for the treatment of functional dyspepsia. Given that acotiamide enhances gastric motility in conscious dogs and rats, we assessed the in vitro effects of this drug on the contraction of guinea pig stomach strips and on acetylcholinest
PMID 26418413

Randomized, Controlled, Multi-center Trial: Comparing the Safety and Efficacy of DA-9701 and Itopride Hydrochloride in Patients With Functional Dyspepsia.

Choi MG1, Rhee PL2, Park H3, Lee OY4, Lee KJ5, Choi SC6, Seol SY7, Chun HJ8, Rew JS9, Lee DH10, Song GA11, Jung HY12, Jeong HY13, Sung IK14, Lee JS15, Lee ST16, Kim SK17, Shin YW18.
Journal of neurogastroenterology and motility.J Neurogastroenterol Motil.2015 Jul 30;21(3):414-22. doi: 10.5056/jnm14117.
BACKGROUND/AIMS: Therapies of functional dyspepsia (FD) are limited. DA-9701 is a novel prokinetic agent formulated with Pharbitis semen and Corydalis Tuber. We aimed to assess the efficacy of DA-9701 compared with itopride in FD patients.METHODS: Patients with FD randomly received either itopride 5
PMID 26130637

Japanese Journal

慢性便秘症患者を対象としたルビプロストン投与時の悪心に対するイトプリド塩酸塩併用の有用性

消化器内科 59(6), 574-582, 2014-12
NAID 40020301655

六君子湯が有効であった呑気症の1症例

日小外会誌 46(6), 946-950, 2010
NAID 110007817468

Itopride hydrochlorideの主要代謝物の心筋細胞遅延整流K〔+〕電流に対する影響

米子医学雑誌 56(5), 188-193, 2005
NAID 40006906283

Related Links

Itopride hydrochloride ≥98% (HPLC) | Sigma-Aldrich

Itopride hydrochloride enhances the gastrointestinal motility by blocking the activity of dopamine on the D2 receptors, on the post-synaptic cholinergic nerves and by inducing the liberation of acetylcholine in the myenteric plexus. It

Itopride hydrochloride | C20H27ClN2O4 - PubChem

Itopride hydrochloride | C20H27ClN2O4 | CID 129791 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ...

Detailed Information About Ganaton: Use, Side Effects ...

Itopride hydrochloride 150mg Extended Release Indications: Itopride hydrochloride is used in the treatment of gastrointestinal symptoms of functional, nonulcer dyspepsia (chronic gastritis) i.e., sensation of bloating, early satiety, upper abdominal pain or discomfort, anorexia, heartburn, nausea and vomiting.