イソクエン酸
- 関
- isocitrate
WordNet
- street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
- any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
- having the characteristics of an acid; "an acid reaction"
PrepTutorEJDIC
- 酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/04/15 07:53:22」(JST)
[Wiki en表示]
Isocitric acid
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Names |
IUPAC name
1-Hydroxypropane-1,2,3-tricarboxylic acid
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Identifiers |
CAS Number
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3D model (Jmol)
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ChEBI |
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ChemSpider |
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DrugBank |
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ECHA InfoCard |
100.005.713 |
KEGG |
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MeSH |
Isocitrate |
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InChI
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InChI=1S/C6H8O7/c7-3(8)1-2(5(10)11)4(9)6(12)13/h2,4,9H,1H2,(H,7,8)(H,10,11)(H,12,13) Y
Key: ODBLHEXUDAPZAU-UHFFFAOYSA-N Y
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InChI=1/C6H8O7/c7-3(8)1-2(5(10)11)4(9)6(12)13/h2,4,9H,1H2,(H,7,8)(H,10,11)(H,12,13)
Key: ODBLHEXUDAPZAU-UHFFFAOYAX
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SMILES
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O=C(O)C(CC(=O)O)C(O)C(=O)O
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Properties |
Chemical formula
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C6H8O7 |
Molar mass |
192.124 |
Melting point |
105 °C (221 °F; 378 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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N verify (what is YN ?) |
Infobox references |
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Isocitric acid is a structural isomer of citric acid. Salts and esters of isocitric acid are known as isocitrates. The isocitrate anion is a substrate of the citric acid cycle. Isocitrate is formed from citrate with the help of the enzyme aconitase, and is acted upon by isocitrate dehydrogenase.
Isocitric acid is commonly used as a marker to detect the authenticity and quality of fruit products, most often citrus juices. In authentic orange juice, for example, the ratio of citric acid to D-isocitric acid is usually less than 130. An isocitric acid value higher than this may be indicative of fruit juice adulteration.[1]
Interactive pathway map
Click on genes, proteins and metabolites below to link to respective articles. [§ 1]
[[File:
|{{{bSize}}}px|alt=TCA Cycle edit]]
File:TCACycle WP78.png
TCA Cycle edit
- ^ The interactive pathway map can be edited at WikiPathways: "TCACycle_WP78".
See also
- Citric Acid
- Tartaric Acid
- Malic Acid
References
- ^ Saavedra, L.; Garcia, A.; Barbas, C. (9 June 2000). "Development and validation of a capillary electrophoresis method for direct measurement of isocitric, citric, tartaric and malic acids as adulteration markers in orange juice". Journal of Chromatography A. 881 (1-2): 395–401. PMID 10905722.
Citric acid cycle metabolic pathway
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Oxaloacetate |
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Malate |
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Fumarate |
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Succinate |
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Succinyl-CoA |
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Acetyl-CoA |
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NADH + H+ |
NAD+ |
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H2O |
FADH2 |
FAD |
CoA + ATP(GTP) |
Pi + ADP(GDP) |
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H2O |
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NADH + H+ + CO2 |
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CoA |
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NAD+ |
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H2O |
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H2O |
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NAD(P)+ |
NAD(P)H + H+ |
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CO2 |
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Citrate |
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cis-Aconitate |
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Isocitrate |
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Oxalosuccinate |
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α-Ketoglutarate |
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UpToDate Contents
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English Journal
- The effect of oxalic and itaconic acids on threo-Ds-isocitric acid production from rapeseed oil by Yarrowia lipolytica.
- Kamzolova SV1, Allayarov RK2, Lunina JN2, Morgunov IG2.
- Bioresource technology.Bioresour Technol.2016 Apr;206:128-33. doi: 10.1016/j.biortech.2016.01.092. Epub 2016 Feb 1.
- The effect of oxalic and itaconic acids, the inhibitors of the isocitrate lyase, on the production of isocitric acid by the wild strain Yarrowia lipolytica VKM Y-2373 grown in the medium containing rapeseed oil was studied. In the presence of oxalic and itaconic acids, strain Y. lipolytica accumulat
- PMID 26851896
- Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis.
- Yoshimi N1,2, Futamura T2, Bergen SE3, Iwayama Y4, Ishima T1, Sellgren C5, Ekman CJ6, Jakobsson J7, Pålsson E7, Kakumoto K8, Ohgi Y2, Yoshikawa T4, Landén M3,7, Hashimoto K1.
- Molecular psychiatry.Mol Psychiatry.2016 Jan 19. doi: 10.1038/mp.2015.217. [Epub ahead of print]
- Although evidence for mitochondrial dysfunction in the pathogenesis of bipolar disorder (BD) has been reported, the precise biological basis remains unknown, hampering the search for novel biomarkers. In this study, we performed metabolomics of cerebrospinal fluid (CSF) from male BD patients (n=54)
- PMID 26782057
- Implication of Metabolomic profiles to wide thermoneutral zone in Mongolian gerbils (Meriones unguiculatus).
- Shi Y1,2, Wang D1.
- Integrative zoology.Integr Zool.2016 Jan 9. doi: 10.1111/1749-4877.12179. [Epub ahead of print]
- Mongolian gerbils (Meriones unguiculatus) have evolved a wide thermoneutral zone (26.5-38.9 ºC) and high upper critical temperature, and appear to have a high tolerance for heat exposure. Here, we use a metabolomic approach to measure global metabolite profiles for gerbils between lower (27 ºC) an
- PMID 26749160
Japanese Journal
- 新規な配位子交換―キャピラリー電気泳動法による有機酸及び単糖の光学異性体分析
- 小玉 修嗣,赤羽 麻美,會澤 宣一,多賀 淳,山本 敦,早川 和一
- 分析化学 63(5), 371-382, 2014
- キャピラリー電気泳動法は分離効率が高く,多種多様な光学分割剤を任意の濃度で利用できるため,光学異性体分析には有効な方法である.この方法が初めて光学異性体分析に適用されたのは,アミノ酸を配位子に,Cu(II)イオンを中心イオンに用いた配位子交換法によりアミノ酸を光学異性体分離した研究である.その後,配位子交換法はアミノ酸の光学異性体分析法の一つと位置付けられてきた.著者らは,従来の配位子交換法を拡張 …
- NAID 130004428005
- ハナビラタケ子実体の貯蔵中における炭水化物および有機酸の変化
- 吉田 博,内田 美和子,小野 優子
- 日本きのこ学会誌 : mushroom science and biotechnology 14(2), 81-90, 2006-07-25
- ハナビラタケ子実体中の5貯蔵温度(30,20,10,5,0℃)における無包装貯蔵および密封包装貯蔵(厚さ100μmのポリエチレンフィルム袋)の低分子炭水化物,酢酸可溶多糖(グリコーゲン様多糖),有機酸含量の変化について検討した.(1)ハナビラタケの無包装貯蔵の鮮度保持期間は,30℃で4日,20℃で7日,10℃で14日,5℃で18日,0℃で19日であった.厚さ100μmのポリエチレンフィルム袋を用い …
- NAID 110008675280
- ハナビラタケ菌糸体の栄養生長にともなう炭水化物および有機酸の変遷
- 吉田 博
- 日本きのこ学会誌 : mushroom science and biotechnology 13(3), 149-155, 2005-10-25
- ハナビラタケの栄養生長にともなう菌糸体中の低分子炭水化物,グリコーゲンおよび有機酸の分布変化を検討した.培地中にギ酸,酢酸,シュウ酸,コハク酸,フマル酸,リンゴ酸,クエン酸およびイソクエン酸が集積し,シュウ酸の集積は他の有機酸類よりも顕著であった.乾燥重量あたり,栄養生長中の菌糸体の低分子炭水化物含量は9.5〜15.5%の範囲であった.菌糸体からトレハロース,グルコース,フルクトース,アラビトール …
- NAID 110008675270
Related Links
- Isocitric acid definition, a major intermediate in the Krebs cycle, having the formula C 6 H 8 O 7 . See more. Thesaurus Translate Puzzles & Games Word of the Day Blog Slideshows Apps by Dictionary My Account Log Out Log In ...
- Looking for online definition of isocitric acid in the Medical Dictionary? isocitric acid explanation free. What is isocitric acid? Meaning of isocitric acid medical term. What does isocitric acid mean? Isocitric acid | definition of ? ...
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- 関
- isocitric acid