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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/07/25 08:53:47」(JST)
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Diodone
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Systematic (IUPAC) name |
(3,5-Diiodo-4-oxo-1(4H)-pyridinyl)acetic acid
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Identifiers |
ATC code |
V08AA10 (WHO) |
PubChem |
CID 9304 |
ChemSpider |
8945 |
Synonyms |
Iodopyracet, pelvirinic acid, umbradilic acid |
Chemical data |
Formula |
C7H5I2NO3 |
Molar mass |
404.928 g/mol |
SMILES
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O=C(O)CN/1/C=C(/I)C(=O)C(\I)=C\1
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InChI
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InChI=1S/C7H5I2NO3/c8-4-1-10(3-6(11)12)2-5(9)7(4)13/h1-2H,3H2,(H,11,12)
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Key:PVBALTLWZVEAIO-UHFFFAOYSA-N
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Diodone is a radiocontrast agent used in urography.[1] It is usually formulated as a salt with diethanolamine.
References
- ^ Wilson, DM; Apter, JT; Schwartz, FD (1970). "A model for measuring renal blood flow from plasma disappearance of iodopyracet". Journal of Applied Physiology 28 (1): 79–88. doi:10.1007/BF00698048. PMID 5409794.
Contrast media (V08)
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X-ray and CT |
Iodinated,
Water soluble
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Nephrotropic,
high osmolar
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- Diatrizoic acid#
- Metrizoic acid
- Iodamide
- Iotalamic acid
- Ioxitalamic acid
- Ioglicic acid
- Acetrizoic acid
- Iocarmic acid
- Methiodal
- Diodone
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Nephrotropic,
low osmolar
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- Metrizamide
- Iohexol#
- Ioxaglic acid
- Iopamidol
- Iopromide
- Iotrolan
- Ioversol
- Iopentol
- Iodixanol
- Iomeprol
- Iobitridol
- Ioxilan
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Hepatotropic
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- Iodoxamic acid
- Iotroxic acid
- Ioglycamic acid
- Adipiodone
- Iobenzamic acid
- Iopanoic acid
- Iocetamic acid
- Sodium iopodate
- Tyropanoic acid
- Calcium iopodate
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Iodinated,
Water insoluble
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- Ethyl esters of iodised fatty acids
- Iopydol
- Propyliodone
- Iofendylate
- Lipiodol
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Non-iodinated
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MRI |
Paramagnetic
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- Gadolinium-based: Gadobenic acid
- Gadobutrol
- Gadodiamide
- Gadofosveset
- Gadolinium
- Gadopentetic acid
- Gadoteric acid
- Gadoteridol
- Gadoversetamide
- Gadoxetic acid
Other: Ferric ammonium citrate
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Superparamagnetic
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- Ferumoxsil
- Ferristene
- Iron oxide, nanoparticles
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Other
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Ultrasound |
- Microspheres of human albumin
- Microparticles of galactose
- Perflenapent
- Microspheres of phospholipids
- Sulfur hexafluoride
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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English Journal
- Coumarin-based, electron-trapping iridium complexes as highly efficient and stable phosphorescent emitters for organic light-emitting diodes.
- Ren X1, Kondakova ME, Giesen DJ, Rajeswaran M, Madaras M, Lenhart WC.
- Inorganic chemistry.Inorg Chem.2010 Feb 15;49(4):1301-3. doi: 10.1021/ic9022097.
- A new class of coumarin-based iridium tris-cyclometalated complexes has been developed. These complexes are highly emissive, with emission colors ranging from green to orange-red. Besides modification of ligand structures, color tuning was realized by incorporation of ligands with different electroc
- PMID 20070119
- Transport of 99mTc-MAG3 via rat renal organic anion transporter 1.
- Shikano N1, Kanai Y, Kawai K, Ishikawa N, Endou H.
- Journal of nuclear medicine : official publication, Society of Nuclear Medicine.J Nucl Med.2004 Jan;45(1):80-5.
- Recently, complementary DNA (cDNA) encoding a p-aminohippurate (PAH) transporter designated rat organic anion transporter 1 (OAT1) was isolated. OAT1, a multispecific organic anion transporter at the basolateral membrane, is exclusively expressed in the middle segment of the proximal tubule in the r
- PMID 14734677
- [The characteristics of surgical cholangiography].
- Beliaev LB, Pikuza VI, Iudin EV, Sukhanov AI, Kotsiuba AK, Starodubov VS.
- Voenno-medit︠s︡inskiĭ zhurnal.Voen Med Zh.1999 Apr;320(4):40-3.
- PMID 10382358
Japanese Journal
- Betamipronの腎毒性軽減作用とその作用機序 (2):腎排泄挙動との関連
- 長沼 英夫,広内 康邦,川原 幸則,乾 賢一,谷川原 祐介,安原 真人,堀 了平,桑原 章吾
- CHEMOTHERAPY 39(Supplement3), 178-189, 1991
- … PAPMのCLrは, 高用量のbetamipron (BP) の点滴により低下したが, probenecidやiodopyracetを併用した時と比較して小さかった。 …
- NAID 130004197444
- 新規経口用セファロスポリンME1207の生体内活性体ME1206のラット,ウサギおよびイヌにおける腎排せつ機構
- 栗林 尚志,岡本 淳一,小宮 泉
- 薬物動態 6(6), 909-918, 1991
- … ME1206の腎排泄機構について,ラットは定型腎クリアランス法,ウサギおよびイヌではstop-flow法を用い検討した.<BR>ラットにおけるME1206のERは,ME1206を単独で投与したときは3.64であった.それに対して,iodopyracetを併用し尿細管分泌を阻害したときのERは,0.932であった.これらの結果から,ラットにおいてME1206は,糸球体濾過および尿細管分泌により排泄されると考えられる.<BR>イヌにおいて近位尿細管分泌の …
- NAID 130003561473
- Effect of Iodopyracet on Renal Excretion of Sulfamethizole in Rabbits
- KATAYAMA Kazunori,TSUBOTA Emi,ENDOH Makiko,KAKEMI Masawo,KOIZUMI Tamotsu
- Journal of pharmacobio-dynamics 13(3), 179-185, 1990-03
- … To predict quantitatively drug interaction kinetics from the single-drug clearance studies, we examined the effect of iodopyracet (IOD) on sulfamethizole (SMZ) excretion in rabbits. …
- NAID 110003637117
Related Links
- Looking for online definition of iodopyracet in the Medical Dictionary? iodopyracet explanation free. What is iodopyracet? Meaning of iodopyracet medical term. What does iodopyracet mean? Iodopyracet | definition of iodopyracet ...
- Iodopyracet definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now! Thesaurus Translate Puzzles & Games Word of the Day Blog Slideshows Apps by Dictionary Log Out ...
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