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English Journal

Interesterified fat or palm oil as substitutes for partially hydrogenated fat during the perinatal period produces changes in the brain fatty acids profile and increases leukocyte-endothelial interactions in the cerebral microcirculation from the male offspring in adult life.

Misan V1, Estato V2, de Velasco PC1, Spreafico FB1, Magri T1, Dos Santos RM1, Fragoso T1, Souza AS1, Boldarine VT3, Bonomo IT4, Sardinha FL1, Oyama LM3, Tibiriçá E2, Tavares do Carmo Md5.
Brain research.Brain Res.2015 Aug 7;1616:123-33. doi: 10.1016/j.brainres.2015.05.001. Epub 2015 May 14.
We investigated whether maternal intake of normolipidic diets with distinct fatty acid (FA) compositions alters the lipidic profile and influences the inflammatory status of the adult offsprings׳ brains. C57BL/6 female mice during pregnancy and lactation received diets containing either soybean oil
PMID 25982597

Critical differences between two classical surgical approaches for middle cerebral artery occlusion-induced stroke in mice.

Smith HK1, Russell JM1, Granger DN1, Gavins FN2.
Journal of neuroscience methods.J Neurosci Methods.2015 Jul 15;249:99-105. doi: 10.1016/j.jneumeth.2015.04.008. Epub 2015 Apr 30.
BACKGROUND: Stroke is the third leading cause of death and the leading cause of long-term disability in North America. On average, someone in the US has a stroke every 45s, and worldwide, stroke claims 15 million lives each year. Therefore, reliable stroke models are vital to the production of effec
PMID 25936850

FRET based ratiometric Ca(2+) imaging to investigate immune-mediated neuronal and axonal damage processes in experimental autoimmune encephalomyelitis.

Siffrin V1, Birkenstock J2, Luchtman DW2, Gollan R2, Baumgart J3, Niesner RA4, Griesbeck O5, Zipp F2.
Journal of neuroscience methods.J Neurosci Methods.2015 Jul 15;249:8-15. doi: 10.1016/j.jneumeth.2015.04.005. Epub 2015 Apr 10.
BACKGROUND: Irreversible axonal and neuronal damage are the correlate of disability in patients suffering from multiple sclerosis (MS). A sustained increase of cytoplasmic free [Ca(2+)] is a common upstream event of many neuronal and axonal damage processes and could represent an early and potential
PMID 25864804

Salicylic Acid and Jasmonic Acid Pathways are Activated in Spatially Different Domains Around the Infection Site During Effector-Triggered Immunity in Arabidopsis thaliana