WordNet

a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system

PrepTutorEJDIC

=sense organ / 受信装置

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/11/04 10:57:17」(JST)

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The interleukin 11 receptor is a type I cytokine receptor, binding interleukin 11. It is a heterodimer composed of an interleukin 11 receptor alpha subunit and an incompletely characterized beta subunit.^[1]

References

^ Chérel M, Sorel M, Lebeau B, Dubois S, Moreau JF, Bataille R, Minvielle S, Jacques Y (1995). "Molecular cloning of two isoforms of a receptor for the human hematopoietic cytokine interleukin-11". Blood 86 (7): 2534–40. PMID 7670098.

External links

Receptors, Interleukin-11 at the US National Library of Medicine Medical Subject Headings (MeSH)

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UpToDate Contents

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1. 周期性発熱症候群およびその他の自己炎症性疾患：概要 periodic fever syndromes and other autoinflammatory diseases an overview
2. クリオピリン関連周期性発熱症候群および関連疾患 cryopyrin associated periodic syndromes and related disorders
3. IL-1、IL-6、およびRANKLを抑制する生物学的製剤の関節リウマチにおけるランダム化臨床試験 randomized clinical trials in rheumatoid arthritis of biologic agents that inhibit il 1 il 6 and rankl
4. リウマチ性疾患における生物学的製剤の概要 overview of biologic agents in the rheumatic diseases
5. リウマチ性疾患におけるサイトカインネットワーク：治療の意味 cytokine networks in rheumatic diseases implications for therapy

English Journal

IL-6 Improves Energy and Glucose Homeostasis in Obesity via Enhanced Central IL-6 trans-Signaling.

Timper K1, Denson JL1, Steculorum SM1, Heilinger C1, Engström-Ruud L1, Wunderlich CM1, Rose-John S2, Wunderlich FT3, Brüning JC4.
Cell reports.Cell Rep.2017 Apr 11;19(2):267-280. doi: 10.1016/j.celrep.2017.03.043.
PMID 28402851

Therapeutically blocking Interleukin-11 Receptor-α enhances doxorubicin cytotoxicity in high grade type I endometrioid tumours.

Winship A1,2, Van Sinderen M1,2, Rainczuk K1,2, Dimitriadis E1,2,3.
Oncotarget.Oncotarget.2017 Apr 4;8(14):22716-22729. doi: 10.18632/oncotarget.15187.
PMID 28186993

Enhancing Interleukin-6 and Interleukin-11 receptor cleavage.

Lokau J1, Wandel M1, Garbers C2.
The international journal of biochemistry & cell biology.Int J Biochem Cell Biol.2017 Apr;85:6-14. doi: 10.1016/j.biocel.2017.01.014. Epub 2017 Jan 29.
PMID 28143719

Japanese Journal

Glycoprotein 130 Cytokine Signal as a Therapeutic Target Against Cardiovascular Diseases

FUJIO Yasushi,MAEDA Makiko,MOHRI Tomomi,OBANA Masanori,IWAKURA Tomohiko,HAYAMA Akiko,YAMASHITA Tomomi,NAKAYAMA Hiroyuki,AZUMA Junichi
Journal of pharmacological sciences 117(4), 213-222, 2011-12-20
… In this review, we focus on the roles of interleukin-6 (IL-6) family cytokines, also known as glycoprotein 130 (gp130) cytokines, in cardioprotection. … These cytokines make a complex with their specific cytokine receptor <I>α</I>-subunits. … The cytokine-receptor <I>α</I>-subunit complex binds to gp130, a common receptor of the IL-6 family, followed by the activation of JAK/STAT, ERK, and PI3 kinase/Akt pathways. …
NAID 10030453480

Functional expression of the interleukin-11 receptor alpha-chain and evidence of antiapoptotic effects in human colonic epithelial cells

KIESSLING S
J Biol Chem 279, 10304-10315, 2004
NAID 30016356555

★リンクテーブル★

リンク元	「インターロイキン11受容体」「IL-11 receptor」「インターロイキン11レセプター」
拡張検索	「interleukin-11 receptor alpha subunit」
関連記事	「interleukin」「interleukins」