WordNet

first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
the 1st letter of the Greek alphabet
the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
early testing stage of a software or hardware product; "alpha version"
a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
any high mountain

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1. リウマチ性疾患におけるサイトカインネットワーク：治療の意味 cytokine networks in rheumatic diseases implications for therapy
2. 骨格の正常な発達および骨形成ならびに骨吸収の調節 normal skeletal development and regulation of bone formation and resorption
3. 造血細胞移植後の移植片対腫瘍効果の生物学 biology of the graft versus tumor effect following hematopoietic cell transplantation
4. 化学療法に関連した経口毒性 oral toxicity associated with chemotherapy
5. 造血細胞移植後の再発の予防および治療のための免疫療法 immunotherapy for the prevention and treatment of relapse following hematopoietic cell transplantation

Dams-Kozlowska H1, Kwiatkowska-Borowczyk E, Gryska K, Mackiewicz A.
International journal of medical sciences.Int J Med Sci.2013 Jul 9;10(9):1157-65. doi: 10.7150/ijms.5638. Print 2013.
Interleukin-11 (IL-11) displays megakaryopoietic activity. We constructed super-cytokine Hyper- IL11 (H11) by linking soluble IL-11 receptor α (sIL-11Rα) with IL-11, which directly targets β-receptor (gp130) signal transducing subunit. The effects of H11 on hematopoiesis with a focus on megakaryo
PMID 23869192

Yang J1, Zhang W.
Current opinion in oncology.Curr Opin Oncol.2013 Jul;25(4):398-406. doi: 10.1097/CCO.0b013e3283622c1b.
PURPOSE OF REVIEW: Recent translational studies in osteosarcoma are discussed with the purpose to shed light on the new molecular therapeutic targets.RECENT FINDINGS: The genetic aberrations of vascular endothelial growth factor (VEGF), mammalian target of rapamycin, Wnt signaling pathway, the inact
PMID 23666471

Discovering small molecules that inhibit adipogenesis and promote osteoblastogenesis: unique screening and Oncostatin M-like activity.

Nawa K1, Ikeno H, Matsuhashi N, Ogasawara T, Otsuka E.
Differentiation; research in biological diversity.Differentiation.2013 Jul-Sep;86(1-2):65-74. doi: 10.1016/j.diff.2013.07.005. Epub 2013 Aug 30.
Oncostatin M (OSM), one of the IL-6 family cytokines, inhibits adipogenic differentiation and stimulates osteoblastogenic differentiation from human bone marrow mesenchymal stem cells (hBMSCs). This functional study of OSM enabled us to develop a two-dimensional small-molecule screen that shifts hBM
PMID 23995451