インターフェロンアルファコン-1
WordNet
- an antiviral protein produced by cells that have been invaded by a virus; inhibits replication of the virus
PrepTutorEJDIC
- インターフェロン(ウイルス増殖抑制物質)
- インターフェロン (virusの増殖を抑制する)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/02/20 06:07:22」(JST)
[Wiki en表示]
Interferon alfacon-1
Clinical data |
Pregnancy
category |
- US: C (Risk not ruled out)
|
Legal status |
|
Routes of
administration |
Parenteral |
Identifiers |
CAS Number |
118390-30-0 Y |
ATC code |
L03AB09 |
DrugBank |
DB00069 N |
ChemSpider |
none |
Chemical data |
Formula |
C860H1353N227O255S9 |
Molar mass |
19343 g/mol |
NY (what is this?) (verify) |
Interferon alfacon-1 is a recombinant synthetic type I interferon used for the treatment of hairy cell leukemia, malignant melanoma and AIDS-related Kaposi's sarcoma.[1]
References
- ^ DrugBank DB00069
Immunostimulants (L03)
|
|
Endogenous |
Cytokines |
Colony-stimulating factors |
- G-CSF
- Filgrastim / Pegfilgrastim
- Lenograstim
- GM-CSF
- Molgramostim
- Sargramostim
- SCF
|
|
Interferons |
- alpha:
- Albinterferon
- Interferon alfa natural
- Interferon alfa 2a / Peginterferon alfa-2a
- Interferon alfa 2b / Peginterferon alfa-2b
- Interferon alfa n1
- Interferon alfacon-1
- Interferon alpha-n3
- beta:
- Interferon beta natural
- Interferon beta 1a
- Interferon beta 1b
- Interferon gamma
|
|
Interleukins |
|
|
|
Other protein / peptide |
- Growth hormone
- Immunocyanin
- Pegademase
- Prolactin
- Tasonermin
|
|
Other |
- Female sex steroids
- Histamine dihydrochloride
- Poly ICLC
- Vitamin D
|
|
|
Exogenous |
- beta-glucan
- heterocyclic compound
- hydroxyquinoline
- Mifamurtide
- oligopeptides
- Glatiramer acetate
- Thymopentin
- Thymosin α1
- Thymulin
- polyribonucleotide
- Polyinosinic:polycytidylic acid
- thiazolidine
- vaccines
- Bacillus Calmette–Guérin
- Melanoma vaccine
- Sipuleucel-T
|
|
UpToDate Contents
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English Journal
- The economic burden of advanced liver disease among patients with hepatitis C virus: a large state Medicaid perspective.
- Menzin J1, White LA, Nichols C, Deniz B.
- BMC health services research.BMC Health Serv Res.2012 Dec 15;12:459. doi: 10.1186/1472-6963-12-459.
- BACKGROUND: Chronic hepatitis C virus (HCV) may progress to advanced liver disease (ALD), including decompensated cirrhosis and/or hepatocellular carcinoma (HCC). ALD can lead to significant clinical and economic consequences, including liver transplantation. This study evaluated the health care cos
- PMID 23241078
- Pharmacokinetics, tissue distribution, excretion, and antiviral activity of pegylated recombinant human consensus interferon-α variant in monkeys, rats and guinea pigs.
- Cai Y1, Zhang Z, Fan K, Zhang J, Shen W, Li M, Si D, Luo H, Zeng Y, Fu P, Liu C.
- Regulatory peptides.Regul Pept.2012 Jan 10;173(1-3):74-81. doi: 10.1016/j.regpep.2011.09.008. Epub 2011 Oct 8.
- The study aims to characterize the pharmacokinetic, tissue distribution, excretion, and antiviral activity properties of a novel pegylated recombinant human consensus interferon-α variant (PEG-IFN-SA) following a single subcutaneous administration to monkeys, rats and guinea pigs. Studies included:
- PMID 21985916
- Incomplete protein disulphide bond conformation and decreased protein expression result from high cell growth during heterologous protein expression in Pichia pastoris.
- Wu D1, Chu J, Hao YY, Wang YH, Zhuang YP, Zhang SL.
- Journal of biotechnology.J Biotechnol.2012 Jan;157(1):107-12. doi: 10.1016/j.jbiotec.2011.08.032. Epub 2011 Sep 8.
- Previous report has shown that the expression of recombinant human consensus interferon-α mutant (cIFN) in Pichia pastoris in bioreactor is limited with respect to the incorrectly folded cIFN with incomplete disulfide bond, which lead to the degradation and aggregation of cIFN. In this study, the o
- PMID 21924302
Japanese Journal
- 薬剤の臨床 C型肝炎を伴った精神神経疾患に対するInterferon alfacon-1の有効性
- Interferon alfacon-1 and ribavirin versus interferon alpha-2b and ribavirin in the treatment of chronic hepatitis C
- A pilot study of the combination of cyclosporin A and interferon alfacon-1 for the treatment of hepatitis C in previous nonresponder patients
Related Links
- What is Interferon Alfacon 1? Interferon alfacon-1 is made from human proteins. Interferons help the body fight viral infections. Interferon alfacon-1 is used to treat chronic hepatitis C. Interferon alfacon-1 may also be used for purposes not listed in this medication guide. You should not use this medication if ...
- WARNING: FATAL OR LIFE-THREATENING DISORDERS AND RIBAVIRIN ASSOCIATED EFFECTS Alpha interferons, including INFERGEN, cause or aggravate fatal or life-threatening neuropsychiatric, autoimmune, ischemic, and ...
Related Pictures
★リンクテーブル★
[★]
- 英
- interferon alfacon-1
- 商
- アドバフェロン
- 関
- インターフェロンα
[★]
インターフェロンアルファコン
[★]
インターフェロン