- 同
- IAS, 心房中隔
- 同
- 心房中隔, IAS
WordNet
- a partition or wall especially in an ovary
- (anatomy) a dividing partition between two tissues or cavities
PrepTutorEJDIC
- (動・植物体の)隔膜,隔壁
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/05/04 10:27:45」(JST)
[Wiki en表示]
| Interatrial septum |
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Interior of right side of heart. (labeled at left of image, as 'atrial septum')
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Interior of dorsal half of heart of human embryo of about thirty-five days.
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| Identifiers |
| MeSH |
A07.541.459 |
| TA |
A12.1.00.019 |
| FMA |
7108 |
| Anatomical terminology
[edit on Wikidata]
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The interatrial septum is the wall of tissue that separates the right and left atria of the heart.
Contents
- 1 Structure
- 2 Clinical significance
- 3 References
- 4 External links
Structure
Development
The interatrial septum forms during the first and second months of fetal development. Formation of the septum occurs in several stages. The first is the development of the septum primum, a crescent-shaped piece of tissue forming the initial divider between the right and left atria. Because of its crescent shape, the septum primum does not fully occlude the space between left and right atria; the opening that remains is called the ostium primum. During fetal development, this opening allows blood to be shunted from the right atrium to the left.
As the septum primum grows, the ostium primum progressively narrows. Before the ostium primum is completely occluded, a second opening called the ostium secundum begins to form in the septum primum. The ostium secundum allows continued shunting of blood from the right atrium to the left.
To the right of the septum primum, the septum secundum begins to form. This thick, muscular structure initially takes on the same crescent shape as the septum primum, except that it originates anteriorly, whereas the septum primum originates posteriorly. As the septum secundum grows, it leaves a small opening called the foramen ovale. The foramen ovale is continuous with the ostium secundum, again providing for continued shunting of blood.
The ostium secundum progressively enlarges and the size of the septum primum diminishes. Eventually, the septum primum is nothing more than a small flap that covers the foramen ovale on its left side. This flap of tissue is called the valve of the foramen ovale. It opens and closes in response to pressure gradients between the left and right atria. When the pressure is greater in the right atrium, the valve opens; when the pressure is greater in the left atrium, the valve closes. Because the lungs are nonfunctional in fetal life, pressure in the pulmonary circulation is greater than that of the systemic circulation. Consequently, the right atrium is generally under higher pressures than the left atrium, and the valve of the foramen ovale is normally open.
At birth, there is a reversal in the pressure gradient between the atria, resulting in functional closure of the valve of the foramen ovale. Permanent anatomical closure of the foramen ovale occurs with time in normal infants. Inappropriate closure of the foramen ovale results in patent foramen ovale.
Clinical significance
- Atrial septal defect is a relatively common heart malformation that occurs when the interatrial septum fails to develop properly.
References
- Gray's Anatomy: The Anatomical Basis of Clinical Practice, 39th ed. (2005). ISBN 0-443-07168-3
- "Septum, interatrial." Stedman's Medical Dictionary, 27th ed. (2000). ISBN 0-683-40007-X
External links
- Diagram
- Animation, from Indiana University
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Development of the circulatory system
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| Heart |
| Tubular heart |
- Truncus arteriosus
- Bulbus cordis
- Primitive ventricle
- Primitive atrium
- Sinus venosus
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| Septa |
- Atrioventricular cushions/Septum intermedium
- Primary interatrial foramen
- Septum primum
- Septum secundum
- Aorticopulmonary septum
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| Other |
- Atrioventricular canal
- Primary interventricular foramen
- Protein signalling in heart development
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| Vessels |
| Arteries |
- Dorsal aorta
- Aortic arches
- Aortic sac
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| Veins |
- Anterior cardinal vein
- Posterior cardinal vein
- Common cardinal veins
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| Lymph vessels |
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Extraembryonic
hemangiogenesis |
- Blood islands
- Chorion
- Connecting stalk
- Yolk sac
- Placenta
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| Fetal circulation |
- umbilical cord: Umbilical vein → Ductus venosus → Inferior vena cava → Heart → Pulmonary artery → Ductus arteriosus → Aorta → Umbilical artery
- yolk sac: Vitelline veins
- Vitelline arteries
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UpToDate Contents
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English Journal
- Comparative transcriptome analysis of atrial septal defect identifies dysregulated genes during heart septum morphogenesis.
- Wang W1, Niu Z1, Wang Y1, Li Y1, Zou H1, Yang L1, Meng M1, Wei C1, Li Q1, Duan L1, Xie Y1, Zhang Y1, Cao Y1, Han S1, Hou Z2, Jiang L3.
- Gene.Gene.2016 Jan 10;575(2 Pt 1):303-12. doi: 10.1016/j.gene.2015.09.016. Epub 2015 Sep 14.
- Congenital heart disease (CHD) is one of most common birth defects, causing fetal loss and death in newborn all over the world. Atrial and ventricular septal defects were the most common CHD subtypes in most districts. During the past decades, several genes were identified to control atrial septum f
- PMID 26375510
- Platypnoea-orthodeoxia syndrome: to assess breathlessness occurring in the upright position, transthoracic echocardiography should be performed in the upright position.
- Xu B1, Mottram P2, Peverill R2.
- International journal of cardiology.Int J Cardiol.2016 Jan 1;202:636-8. doi: 10.1016/j.ijcard.2015.09.097. Epub 2015 Sep 28.
- PMID 26451790
- Treating cardiac myxomas: a 16-year Chinese single-center study.
- Lin Y1, Xiao J, Chen J, Hong J, Peng H, Kang B, Wu L, Wang Z.
- Journal of cardiovascular medicine (Hagerstown, Md.).J Cardiovasc Med (Hagerstown).2016 Jan;17(1):44-53. doi: 10.2459/JCM.0000000000000114.
- AIMS: Currently, myxoma is the most common type of primary cardiac tumor diagnosed. This article describes the experience over the past 16 years with cases of cardiac myxoma in Chinese patients and elucidated the differences between solid and papillary myxomas.METHODS: The clinical details of 68 pat
- PMID 24933197
Japanese Journal
- 心嚢水貯留と房室ブロックを伴った心臓および乳腺のびまん性大細胞型B細胞リンパ腫
- 富川 武樹,多林 孝之,得平 道英 [他],渡部 玲子,佐川 森彦,根本 朋恵,木村 勇太,高橋 康之,森 茂久,東 守洋,田丸 淳一,木崎 昌弘
- 臨床血液 56(1), 9-15, 2015
- 心臓原発悪性リンパ腫は稀な疾患で，一般に予後不良である。症状の顕在化が遅く，診断が遅れることが多い。今回，我々は心嚢水貯留と房室ブロックにて発症したびまん性大細胞型B細胞リンパ腫(DLBCL)の1症例を経験した。患者は35歳女性。呼吸苦と胸痛，左乳腺の硬い腫瘤を主訴に受診した。心電図検査ではI度房室ブロックを示し，心臓超音波検査では右心房と心房中隔に腫瘤影を認め，多量の心嚢水貯留を認めた。左乳腺腫 …
- NAID 130004920697
- Double Atrial Septum with Interatrial Chamber Formation and Recurrent Paradoxical Embolism
- , , , ,
- Annals of Thoracic and Cardiovascular Surgery 20(Supplement), 829-831, 2014
- … We report a rare case of double atrial septum with an interatrial chamber and stenosis of the inferior vena cava orifice, which lead to recurrent paradoxical embolism, and then highlight the clinical importance of this rare type of congenital heart disease. …
- NAID 130004889703
- 糸永 竜也,中井 真尚,島本 光臣,山崎 文郎,岡田 達治,野村 亮太,寺井 恭彦,宮野 雄太,村田 由祐
- 日本心臓血管外科学会雑誌 43(4), 209-212, 2014
- 症例は24歳女性，呼吸困難，起座呼吸を主訴に前医を受診し，心臓エコー検査にて左房内腫瘤を認めたため当院を紹介されて受診した．左房内を占拠する腫瘤による心不全と診断し，緊急左房内腫瘤切除，自己心膜を用いた左房・心房中隔再建を行った．病理検査にて未分化多形性肉腫と診断された．原発性心臓悪性腫瘍は予後不良であるが，手術による完全切除と放射線・化学療法により再発兆候なく術後1年を経過した1例を経験したので …
- NAID 130004679600
Related Pictures
★リンクテーブル★
[★]
- 英
- interatrial septum (Z), IAS
- 関
- 卵円窩、一次中隔、二次中隔、一次口、二次口、卵円孔
[★]
- 同
- interatrial septum, 心房中隔
心房中隔 interatrial septum
[★]