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WordNet
- a nucleoside that is formed by the deamination of adenosine; used in kidney transplantation to provide a temporary source of sugar
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/06/17 01:24:00」(JST)
[Wiki en表示]
Inosine pranobex |
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IUPAC name
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one : 4-acetamidobenzoic acid : 1-(dimethylamino)propan-2-ol
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Other names
Isoprinosine; Methisoprinol
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Identifiers |
CAS number |
36703-88-5 |
PubChem |
37510 |
ChemSpider |
16736312 |
KEGG |
D01995 |
ATC code |
J05AX05 |
Jmol-3D images |
Image 1 |
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CN(C)CC(C)O.OC(=O)c1ccc(NC(C)=O)cc1.Oc3ncnc2c3ncn2[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O
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InChI=1/C10H12N4O5.C9H9NO3.C5H13NO/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18;1-6(11)10-8-4-2-7(3-5-8)9(12)13;1-5(7)4-6(2)3/h2-4,6-7,10,15-17H,1H2,(H,11,12,18);2-5H,1H3,(H,10,11)(H,12,13);5,7H,4H2,1-3H3/t4-,6-,7-,10-;;/m0../s1
Key: PBJNZCQJMWVIRT-MDQYBHOLBR
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Properties |
Molecular formula |
C52H78N10O17 |
Molar mass |
1115.23 g/mol |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa) |
Infobox references |
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Inosine pranobex (Isoprinosine or Methisoprinol) is a combinatinon of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug. Inosine pranobex has no effect on viral particles itself. It acts as a immunostimulant, an analog of thymus hormones.[1] It is most commonly used to treat the rare measles complication subacute sclerosing panencephalitis in conjunction with intrathecal interferon therapy.[2]
References
- ^ American Cancer Society. "Inosine Pranobex". Retrieved 31 July 2013.
- ^ Campoli-Richards DM, Sorkin EM, Heel RC. (Nov 1986). "Inosine pranobex. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy". Drugs 32 (5): 383–424. doi:10.2165/00003495-198632050-00001.
UpToDate Contents
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English Journal
- Neuro-ophthalmology of subacute sclerosing panencephalitis: two cases and a review of the literature.
- Colpak AI, Erdener SE, Ozgen B, Anlar B, Kansu T.SourceNeuro-Ophthalmology Unit, Institute of Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey.
- Current opinion in ophthalmology.Curr Opin Ophthalmol.2012 Nov;23(6):466-71. doi: 10.1097/ICU.0b013e328358b196.
- PURPOSE OF REVIEW: To review the literature on early visual manifestations of subacute sclerosing panencephalitis (SSPE) with regard to two patients who had visual problems preceding the onset of neurological symptoms. One patient had cortical visual disturbances and the other had visual loss due to
- PMID 23047165
- Psychomotor development after ganciclovir selectively treated congenital and perinatal cytomegalovirus infection.
- Ivanov IS, Popov NT, Moshe RI, Chepisheva EV, Geneva IE, Panova MV, Karparov AA, Shmilev TI, Stefanov RS, Bosheva MN.SourceDepartment of Pediatrics and Medical Genetics, Medical University, Plovdiv, Bulgaria. ivanovist@gmail.com
- Folia medica.Folia Med (Plovdiv).2012 Oct-Dec;54(4):37-44.
- AIM: To study the development of children with selectively treated cytomegalovirus infection.PATIENTS AND METHODS: We studied prospectively a risk group of 12 children with cytomegalovirus infection. These children were diagnosed by serological screening in the first three months after birth and are
- PMID 23441468
- [Efficacy of immunomodulators in children with respiratory diseases in environmentally poor areas].
- Iakupova RSh, Skachkova MA, Choloian SB, Karpova EG.AbstractThe authors evaluated the clinical efficacy and safety of the antiviral and immunomodulatory drug Isoprinosine (inosine pranobex, Teva Pharmaceutical Industries, Ltd) in the treatment of bronchopulmonary diseases in children. One hundred and fifty-two children with acute respiratory diseases and an exacerbation of recurrent respiratory diseases were followed up. The use of Isoprinosine in their combined treatment showed both positive clinical changes and a better immunogram.
- Gigiena i sanitariia.Gig Sanit.2012 May-Jun;(3):33-4.
- The authors evaluated the clinical efficacy and safety of the antiviral and immunomodulatory drug Isoprinosine (inosine pranobex, Teva Pharmaceutical Industries, Ltd) in the treatment of bronchopulmonary diseases in children. One hundred and fifty-two children with acute respiratory diseases and an
- PMID 23088120
Related Links
- Synopsis: Inosine pranobex 1 is a synthetic compound formed from the p-acetamido benzoate salt of N-N dimethylamino-2-propanol and inosine in a 3 : 1 mo ... Amato A, Cavallaro A, Fimiani V. Effetto del metisoprinolo sull ...
- inosine pranobex inosine pran·o·bex (prān'ə-běks') n. An antiviral agent formed from a complex containing inosine.
Related Pictures
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- inosine pranobex
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- イソプリノシン Isoprinosine
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- inosine pranobex
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- inosine pranobex