WordNet

lowering the bodys normal immune response to invasion by foreign substances; can be deliberate (as in lowering the immune response to prevent rejection of a transplanted organ) or incidental (as a side effect of radiotherapy or chemotherapy for cancer)
of or relating to a substance that lowers the bodys normal immune response and induces immunosuppression
of persons whose immune response is inadequate

PrepTutorEJDIC

Thymopentin nanoparticles engineered with high loading efficiency, improved pharmacokinetic properties, and enhanced immunostimulating effect using soybean phospholipid and PHBHHx polymer.

Wu C1, Zhang M, Zhang Z, Wan KW, Ahmed W, Phoenix DA, Elhissi AM, Sun X.
Molecular pharmaceutics.Mol Pharm.2014 Oct 6;11(10):3371-7. doi: 10.1021/mp400722r. Epub 2014 Mar 31.
Formulation of protein and peptide drugs with sustained release properties is crucial to enhance their therapeutic effect and minimize administration frequency. In this study, immunomodulating polymeric systems were designed by manufacturing PHBHHx nanoparticles (NPs) containing thymopentin (TP5). T
PMID 24641274

The Immune Response to Acute Focal Cerebral Ischemia and Associated Post-stroke Immunodepression: A Focused Review.

Famakin BM.
Aging and disease.Aging Dis.2014 Oct 1;5(5):307-26. doi: 10.14336/AD.2014.0500307. eCollection 2014.
It is currently well established that the immune system is activated in response to transient or focal cerebral ischemia. This acute immune activation occurs in response to damage, and injury, to components of the neurovascular unit and is mediated by the innate and adaptive arms of the immune respo
PMID 25276490

Malarial pigment hemozoin impairs chemotactic motility and transendothelial migration of monocytes via 4-hydroxynonenal.

Skorokhod OA1, Barrera V1, Heller R2, Carta F3, Turrini F1, Arese P1, Schwarzer E4.
Free radical biology & medicine.Free Radic Biol Med.2014 Oct;75:210-21. doi: 10.1016/j.freeradbiomed.2014.07.004. Epub 2014 Jul 10.
Natural hemozoin, nHZ, is avidly phagocytosed in vivo and in vitro by human monocytes. The persistence of the undigested β-hematin core of nHZ in the phagocyte lysosome for long periods of time modifies several cellular immune functions. Here we show that nHZ phagocytosis by human primary monocytes
PMID 25017964