WordNet

(genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism (同)genetic mutation, chromosomal_mutation
a change or alteration in form or qualities
(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
informal term for information; "give me the gen on your new line of computers"

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1. 小児における運動過多な運動障害 hyperkinetic movement disorders in children
2. プロトロンビン遺伝子突然変異：血栓症リスクおよび診断 prothrombin gene mutation thrombotic risk and diagnosis
3. 原発性免疫不全症に対する遺伝子治療 gene therapy for primary immunodeficiency
4. 進行非小細胞肺癌に対する遺伝子型による個別治療 personalized genotype directed therapy for advanced non small cell lung cancer
5. 大腸癌の分子遺伝学 molecular genetics of colorectal cancer

Genotoxicity of 1-methylpyrene and 1-hydroxymethylpyrene in Chinese hamster V79-derived cells expressing both human CYP2E1 and SULT1A1.

Jiang H1, Lai Y, Hu K, Chen D, Liu B, Liu Y.
Environmental and molecular mutagenesis.Environ Mol Mutagen.2015 May;56(4):404-11. doi: 10.1002/em.21912. Epub 2014 Sep 22.
1-Methylpyrene (1-MP) is a widespread pollutant that is carcinogenic in animals following metabolic activation. Previous studies have shown that benzylic hydroxylation of 1-MP, catalyzed by multiple CYP isoforms, gives rise to 1-hydroxymethylpyrene (1-HMP), which becomes bioreactive following furthe
PMID 25243916

Scheffler A1, Albrecht AE1, Esch HL1, Lehmann L2.
Toxicology letters.Toxicol Lett.2015 Apr 16;234(2):81-91. doi: 10.1016/j.toxlet.2015.02.013. Epub 2015 Feb 19.
After consumption of red clover-based dietary supplements, plasma concentrations of the isoflavone irilone (IRI) equal that of the well-investigated daidzein. Since some isoflavones are genotoxic, the potential of IRI to induce mutations was investigated. Gene mutations were determined by hypoxanthi
PMID 25703823

In vitro evaluation of genotoxic effects under magnetic resonant coupling wireless power transfer.

Mizuno K1, Shinohara N2, Miyakoshi J3.
International journal of environmental research and public health.Int J Environ Res Public Health.2015 Apr 7;12(4):3853-63. doi: 10.3390/ijerph120403853.
Wireless power transfer (WPT) technology using the resonant coupling phenomenon has been widely studied, but there are very few studies concerning the possible relationship between WPT exposure and human health. In this study, we investigated whether exposure to magnetic resonant coupling WPT has ge
PMID 25853218