UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 続発性無月経の評価およびマネージメントevaluation and management of secondary amenorrhea [show details]
…associated with FSH that is normal or low suggests the possibility of secondary (pituitary or hypothalamic) hypogonadism, either structural or functional. Interpretation of the serum E2 should also take into …
2. 男性における続発性性腺機能低下の原因causes of secondary hypogonadism in males [show details]
…cell histiocytosis (eosinophilic granuloma) can cause hypothalamic hypogonadism, while iron deposition in hemochromatosis can cause pituitary hypogonadism. Treatment of the underlying disease may improve gonadotropin …
3. 機能性視床下部性無月経:評価とマネージメントfunctional hypothalamic amenorrhea evaluation and management [show details]
…energy expenditure, or both) and stress are common causes of hypogonadotropic hypogonadism in women. Functional hypothalamic amenorrhea (FHA) is the term used to describe amenorrhea that results from such …
4. 性腺機能低下を呈する男性の臨床的特徴および診断clinical features and diagnosis of male hypogonadism [show details]
…weight loss. However, severe obesity (body mass index [BMI] >40 kg/m²) may cause hypothalamic hypogonadism as well as the binding abnormality . Measurement of the serum free testosterone in a laboratory …
5. 性腺刺激ホルモン放出ホルモン単独欠乏症（特発性低ゴナドトロピン性性腺機能低下症）isolated gonadotropin releasing hormone deficiency idiopathic hypogonadotropic hypogonadism [show details]
… to as idiopathic hypogonadotropic hypogonadism (IHH), is a family of genetic disorders that are associated with defects in the production and/or action of hypothalamic peptide that controls human reproduction …

English Journal

A comprehensive diagnostic approach to detect underlying causes of obesity in adults.

van der Valk ES, van den Akker ELT, Savas M, Kleinendorst L, Visser JA, Van Haelst MM, Sharma AM, van Rossum EFC.
Obesity reviews : an official journal of the International Association for the Study of Obesity. 2019 Jun;20(6)795-804.
Obesity is a worldwide growing problem. When confronted with obesity, many health care providers focus on direct treatment of the consequences of adiposity. We plead for adequate diagnostics first, followed by an individualized treatment. We provide experience-based and evidence-based practical reco
PMID 30821060

Pituitary pathology in traumatic brain injury: a review.

Sav A, Rotondo F, Syro LV, Serna CA, Kovacs K.
Pituitary. 2019 Jun;22(3)201-211.
Traumatic brain injury most commonly affects young adults under the age of 35 and frequently results in reduced quality of life, disability, and death. In long-term survivors, hypopituitarism is a common complication. Pituitary dysfunction occurs in approximately 20-40% of patients diagnosed with mo
PMID 30927184

Comparison of anthropometric measures for evaluating the association between hypogonadism and hypothalamic-pituitary-gonadal hormones in a Taiwanese population.

Chen CY, Lee CP, Chen Y.
Rejuvenation research. 2019 May;().
Objective To investigate the degree of association between levels of sex hormones and anthropometric indices in male population. Methods A cross-sectional survey was conducted between July 2014 and July, 2016, in a men's health polyclinic in Taiwan. Body mass index (BMI), waist circumference (WC), w
PMID 31084407

Japanese Journal

Plasma kisspeptin levels in male cases with hypogonadism

Kotani Masato,Katagiri Fumihiko,Hirai Tsuyoshi,Kagawa Jiro
Endocrine Journal 61(11), 1137-1140, 2014
… The hypothalamic hormone kisspeptin (metastin) regulates human reproduction by modulating gonadotropin-releasing hormone (GnRH) secretion. … In this study, we measured plasma kisspeptin levels in four male cases with hypogonadism and seven normal male controls using enzyme immunoassay (EIA) to elucidate the clinical implications of kisspeptin levels in male hypogonadism. …
NAID 130004677956

男性更年期外来受診を契機に発見された鞍上部嚢胞性腫瘍による汎下垂体機能低下症の1例

山本致之,高田晋吾,金城孝則 [他],野々村大地,米田傑,野村広徳,鄭則秀,松宮清美,大楠崇浩
泌尿器科紀要 = Acta urologica Japonica 59(10), 683-686, 2013-10
… A 74-year-old man who was referred to our late onset hypogonadism clinic presented with sweating and loss of appetite. … We considered this mass caused hypothalamic hypopituitarism. …
NAID 120005347150

Evaluation of the isokinetic muscle strength, balance and anaerobic performance in patients with young male hypogonadism

Aydogan Umit,Eroglu Ali,Akbulut Halil,Yildiz Yavuz,Gok Deniz Engin,Sonmez Alper,Aydin Taner,Bolu Erol,Saglam Kenan
Endocrine Journal 59(4), 321-327, 2012
… Hypogonadism is a clinical condition that occurs due to infrequent abnormalities in the hypothalamic-pituitary-gonadal (HPG) axis in adolescence. … 30 young male patients with congenital hypogonadotropic hypogonadism (CHH) and 20 healthy young males were included in the present study. …
NAID 130004443798