adj.

肥大性の、肥大型の、肥厚性の、肥大症の

関: hyperplastic

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/11/18 16:52:11」(JST)

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Hypertrophy results from an increase in cell size, while hyperplasia is from an increase in cell number.

Hypertrophy (from Greek ὑπέρ "excess" + τροφή "nourishment") is the increase in the volume of an organ or tissue due to the enlargement of its component cells. It should be distinguished from hyperplasia, in which the cells remain approximately the same size but increase in number. Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the hormonally-induced proliferation and enlargement of the cells of the uterus during pregnancy.

Examples of hypertrophy

Muscular hypertrophy

Main article: Muscle hypertrophy

One of the two most common and visible forms of organ hypertrophy occurs in skeletal muscles in response to strength training (known as muscle hypertrophy). Depending on the type of training, the hypertrophy can occur through increased sarcoplasmic volume or increased contractile proteins.

Ventricular hypertrophy

Main article: Ventricular hypertrophy

Ventricular hypertrophy is the increase in size of the ventricles of the heart. Changes can be beneficial or healthy if they occur in response to aerobic or anaerobic exercise, but ventricular hypertrophy is generally associated with pathological changes due to high blood pressure or other disease states.

Hypertrophy of the breasts

Main article: Gigantomastia

Gigantomastia is the extreme growth of the breasts, i.e. 10 pounds (5 kg) per breast and more. In severe cases it is possible for women to have breasts that weigh well in excess of 20 lb (9 kg) each. Gigantomastia can occur as a rare complication of pregnancy, but also with the more frequently juvenile gigantomastia during puberty (virginal breast hypertrophy).

Hypertrophy of the clitoris

Main article: Clitoromegaly

In the most pronounced cases, clitoromegaly is a symptom of intersexuality since the large clitoris resembles a penis (the different grade of genital ambiguity is commonly measured by the Prader classification ranging, in ascending order of masculinisation, from 1: Female external genitalia with clitoromegaly through 5: Pseudo-phallus looking like normal male external genitalia).

External links

University of California Muscle Physiology Home Page: Hypertrophy

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1. 肥大型心筋症の臨床症状、診断、および評価 clinical manifestations diagnosis and evaluation of hypertrophic cardiomyopathy
2. 肥大型心筋症における心室性不整脈および突然死の評価およびマネージメント assessment and management of ventricular arrhythmias and sudden death risk in hypertrophic cardiomyopathy
3. 肥大型心筋症における内科的治療 medical therapy in hypertrophic cardiomyopathy
4. 肥大型心筋症の遺伝学 genetics of hypertrophic cardiomyopathy
5. 肥大型心筋症における流出路閉塞の非薬理学的治療 nonpharmacologic treatment of outflow obstruction in hypertrophic cardiomyopathy

English Journal

Administration of Pigment Epithelium-Derived Factor Inhibits Airway Inflammation and Remodeling in Chronic OVA-Induced Mice via VEGF Suppression.

Zha W1, Su M1, Huang M1, Cai J2, Du Q3.
Allergy, asthma & immunology research.Allergy Asthma Immunol Res.2016 Mar;8(2):161-9. doi: 10.4168/aair.2016.8.2.161. Epub 2015 Nov 2.
PURPOSE: Pigment epithelium-derived factor (PEDF) is a recently discovered antiangiogenesis protein. PEDF possesses powerful anti-inflammatory, antioxidative, antiangiogenic, and antifibrosis properties. It has been reported that PEDF can regulate vascular endothelial growth factor (VEGF) expression
PMID 26739410

Complete mitochondrial genome sequence and mutations of the cardiac hypertrophy model inbred rat strain (Muridae; Rattus).

Zhu R1, Meng ZL1, Chen L1, Chen W1, Wang H2, Hong YQ1.
Mitochondrial DNA.Mitochondrial DNA.2016 Mar;27(2):1165-6. doi: 10.3109/19401736.2014.936420. Epub 2014 Aug 11.
In the present work we undertook the complete mitochondrial genome sequencing of a important cardiac hypertrophy model inbred rat strain for the first time. The total length of the mitogenome was 16,308 bp. It harbored 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes and 1 non
PMID 25109625

Transition of 1628C > T in mitochondrial tRNA(Val) gene should not be regarded as a mutation associated with hypertrophic cardiomyopathy.

Zhu J1, Zhang X1, Li L1.
Mitochondrial DNA.Mitochondrial DNA.2016 Mar;27(2):1340-2. doi: 10.3109/19401736.2014.945580. Epub 2014 Aug 6.
Diagnosis of hypertrophic cardiomyopathy (HCM) involved the screening for the candidate pathogenic mitochondrial DNA (mtDNA) mutations. However, a poor genotype to phenotype correction is common. Neutral polymorphisms in mt-tRNA gene are recognized as a potential cause for HCM. Thus, assigning the p
PMID 25097009

Japanese Journal

閉塞性肥大型心筋症合併妊娠の帝王切開で子宮収縮薬による循環変動に対しβ遮断薬が有用であった1症例

束野友里,杉田道子,生田義浩 [他]
麻酔 64(6), 642-646, 2015-06
NAID 40020497985

症例心室中隔心筋切除術とlow-profile生体弁による僧帽弁置換術を行った閉塞性肥大型心筋症の1例

古川貢之,阪口修平,中村栄作 [他]
胸部外科 = The Japanese journal of thoracic surgery 68(6), 449-452, 2015-06
NAID 40020490998

QTc Interval Prolongation Predicts Arrhythmia Recurrence After Catheter Ablation of Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy

Wen Song-Nan,Liu Nian,Li Song-Nan [他]
Circulation journal : official journal of the Japanese Circulation Society 79(5), 1024-1030, 2015-05
NAID 40020437056

「肥厚性」

Hypertrophy
	Classification and external resources
MeSH	D006984

　　[★]

英: hypertrophic、hyperplastic
関: 過形成、過形成性、肥大症、肥大性、肥大型

「hyperplastic」

　　[★]

adj.

過形成性の、過形成の、肥厚性の

関: hyperplasia、hypertrophic

「肥大型」

　　[★]

英: hypertrophic
関: 肥厚性、肥大症、肥大性

「肥大性」

　　[★]

英: hypertrophic
関: 肥厚性、肥大症、肥大型

「肥大症」

　　[★]

英: hypertrophic
関: 肥厚性、肥大性、肥大型

「hypertrophic chondrocyte」

　　[★]

肥大軟骨細胞、肥大化軟骨細胞

「pseudohypertrophic muscular dystrophy」

　　[★]

関: Duchenne muscular dystrophy

「dilated phase of hypertrophic cardiomyopathy」

　　[★] 拡張相肥大型心筋症

リンク元	「肥厚性」「hyperplastic」「肥大型」「肥大性」「肥大症」
拡張検索	「hypertrophic chondrocyte」「pseudohypertrophic muscular dystrophy」「dilated phase of hypertrophic cardiomyopathy」

匿名

検索

案内

案内

hypertrophic