WordNet

sclerosis of the arterial walls (同)arterial sclerosis, hardening of the arteries, induration of the arteries, coronary-artery disease

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Deficiency of endothelial CXCR4 reduces reendothelialization and enhances neointimal hyperplasia after vascular injury in atherosclerosis-prone mice.

Noels H1, Zhou B2, Tilstam PV2, Theelen W2, Li X2, Pawig L2, Schmitz C2, Akhtar S2, Simsekyilmaz S2, Shagdarsuren E2, Schober A2, Adams RH2, Bernhagen J2, Liehn EA2, Döring Y2, Weber C1.
Arteriosclerosis, thrombosis, and vascular biology.Arterioscler Thromb Vasc Biol.2014 Jun;34(6):1209-20. doi: 10.1161/ATVBAHA.113.302878. Epub 2014 Apr 10.
OBJECTIVE: The Cxcl12/Cxcr4 chemokine ligand/receptor axis mediates the mobilization of smooth muscle cell progenitors, driving injury-induced neointimal hyperplasia. This study aimed to investigate the role of endothelial Cxcr4 in neointima formation.APPROACH AND RESULTS: β-Galactosidase staining
PMID 24723559

Atheroprotective remodelling of vascular dermatan sulphate proteoglycans in response to hypercholesterolaemia in a rat model.

Oberkersch R1, Maccari F, Bravo AI, Volpi N, Gazzaniga S, Calabrese GC.
International journal of experimental pathology.Int J Exp Pathol.2014 Jun;95(3):181-90. doi: 10.1111/iep.12072. Epub 2014 Mar 7.
Proteoglycan accumulation within the arterial intima has been implicated in atherosclerosis progression in humans. Nevertheless, hypercholesterolaemia is unable to induce intimal thickening and atheroma plaque development in rats. The study was performed to analyse proteoglycans modifications in rat
PMID 24602133