Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/15 12:33:42」(JST)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Transport and binding of tumor necrosis factor-α in articular cartilage depend on its quaternary structure.

Byun S, Sinskey YL, Lu YC, Frank EH, Grodzinsky AJ.SourceDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.
Archives of biochemistry and biophysics.Arch Biochem Biophys.2013 Dec;540(1-2):1-8. doi: 10.1016/j.abb.2013.10.003. Epub 2013 Oct 14.
The effect of tumor necrosis factor-α (TNFα) on cartilage matrix degradation is mediated by its transport and binding within the extracellular matrix (ECM) of the tissue, which mediates availability to cell receptors. Since the bioactive form of TNFα is a homotrimer of monomeric subunits, convers
PMID 24135706

Development and use of an atomistic CHARMM-based forcefield for peptoid simulation.

Mirijanian DT, Mannige RV, Zuckermann RN, Whitelam S.SourceMolecular Foundry, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California, 94720.
Journal of computational chemistry.J Comput Chem.2013 Nov 29. doi: 10.1002/jcc.23478. [Epub ahead of print]
Peptoids are positional isomers of peptides: peptoid sidechains are attached to backbone nitrogens rather than α-carbons. Peptoids constitute a class of sequence-specific polymers resistant to biological degradation and potentially as diverse, structurally and functionally, as proteins. While molec
PMID 24293222

Biochemical Analysis and Structure Determination of Bacterial Acetyltransferases Responsible for the Biosynthesis of UDP-N,N'-Diacetylbacillosamine.

Morrison MJ, Imperiali B.SourceFrom the Departments of Chemistry and Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139.
The Journal of biological chemistry.J Biol Chem.2013 Nov 8;288(45):32248-60. doi: 10.1074/jbc.M113.510560. Epub 2013 Sep 24.
UDP-N,N'-diacetylbacillosamine (UDP-diNAcBac) is a unique carbohydrate produced by a number of bacterial species and has been implicated in pathogenesis. The terminal step in the formation of this important bacterial sugar is catalyzed by an acetyl-CoA (AcCoA)-dependent acetyltransferase in both N-
PMID 24064219