WordNet

the 21st letter of the Roman alphabet (同)u
(chiefly British) of or appropriate to the upper classes especially in language use

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1. 様々な抗核抗体 miscellaneous antinuclear antibodies
2. 混合性結合組織病における抗U1-RNP抗体 anti u1 rnp antibodies in mixed connective tissue disease
3. 混合性結合組織病の臨床症状 clinical manifestations of mixed connective tissue disease

Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cells.

Meininger I1, Griesbach RA1,2, Hu D3,4, Gehring T1, Seeholzer T1, Bertossi A1, Kranich J4, Oeckinghaus A1, Eitelhuber AC1, Greczmiel U1, Gewies A5,6, Schmidt-Supprian M6,7, Ruland J5,6,8, Brocker T4, Heissmeyer V3,4, Heyd F9, Krappmann D1.
Nature communications.Nat Commun.2016 Apr 12;7:11292. doi: 10.1038/ncomms11292.
MALT1 channels proximal T-cell receptor (TCR) signalling to downstream signalling pathways. With MALT1A and MALT1B two conserved splice variants exist and we demonstrate here that MALT1 alternative splicing supports optimal T-cell activation. Inclusion of exon7 in MALT1A facilitates the recruitment
PMID 27068814

Nuclear distribution of eIF3g and its interacting nuclear proteins in breast cancer cells.

Zheng Q1, Liu H2, Ye J1, Zhang H3, Jia Z2, Cao J1.
Molecular medicine reports.Mol Med Rep.2016 Apr;13(4):2973-80. doi: 10.3892/mmr.2016.4935. Epub 2016 Feb 23.
Eukaryotic translation initiation factor 3 subunit g (eIF3g) is a core subunit of the eukaryotic translation initiation factor 3 complex, and is important in the initiation of translation. It is also involved in caspase-mediated apoptosis, and is upregulated in multidrug-resistant cancer cells. In
PMID 26935993

Functional requirements of AID's higher order structures and their interaction with RNA-binding proteins.

Mondal S1, Begum NA1, Hu W1, Honjo T2.
Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2016 Feb 29. pii: 201601678. [Epub ahead of print]
Activation-induced cytidine deaminase (AID) is essential for the somatic hypermutation (SHM) and class-switch recombination (CSR) of Ig genes. Although both the N and C termini of AID have unique functions in DNA cleavage and recombination, respectively, during SHM and CSR, their molecular mechanism
PMID 26929374

An X-chromosome RNA-binding motif protein (RBMX) is required for proper kinetochore formation

Hann Lee Mei,Lin Linyen,Takata Hideaki [他],MORIMOTO Akihiro,UCHIYAMA Susumu,MATSUNAGA Sachihiro,FUKUI Kiichi
Chromosome science 14(1), 17-21, 2012-03-01
RBMX is an RNA-binding motif protein identified as a component of purified human metaphase chromosomes. We have analyzed the functional significance of RBMX by electron microscopy (EM) in combination …
NAID 10030317380