熱性疱疹
WordNet
- viral diseases causing eruptions of the skin or mucous membrane
- any of the animal viruses that cause painful blisters on the skin (同)herpes_virus
PrepTutorEJDIC
- 疱疹(ほうしん)
UpToDate Contents
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English Journal
- Acyclovir Lauriad®: a muco-adhesive buccal tablet for the treatment of recurrent herpes labialis.
- Downing C, Moayyad J, Tamirisa A, Tyring S.Author information Center for Clinical Studies, 451 N. Texas Ave, Webster, TX 77598, USA.AbstractThe treatment of recurrent herpes labialis remains a challenge in the 21st century. The virus is ubiquitous and there is no vaccine against the disease. Although recurrence episodes are usually of shorter duration than the primary episode, they are debilitating to patients and there is significant stigma associated with the disease. Acyclovir Lauriad® is a new topical agent that was approved by the US FDA in 2013 for the treatment of recurrent herpes labialis, which affects approximately 20-40% of the population worldwide. The drug is a muco-adhesive tablet, applied to the upper gum at the onset of prodromal symptoms. Utilizing Lauriad® technology, a biologically active compound traverses the mucous membrane to deliver a high concentration of acyclovir directly to the site of the herpes simplex virus infection. Data from a Phase III clinical trial shows that this may be a promising therapy for patients with recurrent herpes labialis.
- Expert review of anti-infective therapy.Expert Rev Anti Infect Ther.2014 Jan 23. [Epub ahead of print]
- The treatment of recurrent herpes labialis remains a challenge in the 21st century. The virus is ubiquitous and there is no vaccine against the disease. Although recurrence episodes are usually of shorter duration than the primary episode, they are debilitating to patients and there is significant s
- PMID 24456534
- Combination Antiviral--Anti-Inflammatory Treatment for Recurrent Herpes Simplex Labialis: Rationale and Efficacy Demonstrated with a Novel Composite Efficacy Measure.
- Hull CM, Levin MJ, Tyring SK, Spruance SL.Author information University of Utah, Salt Lake City, UT.AbstractHistorically, the primary target for research and treatment in recurrent herpes simplex labialis (HSL) has been limited to inhibiting herpes simplex virus (HSV) replication. Antiviral monotherapy, however, has proven only marginally effective in curtailing the duration and severity of recurrent lesions. Recently, the role of inflammation in the progression and resolution of recurrences has been identified as an additional target. This was evaluated in a randomized study comparing combination topical acyclovir 5%/hydrocortisone 1% cream (AHC) with acyclovir 5% alone (AC; in AHC vehicle) and vehicle. The efficacy of each topical therapy was evaluated with cumulative lesion size, a novel composite efficacy endpoint incorporating episode duration, lesion area, and proportion of nonulcerative lesions. In that study, cumulative lesion area was significantly decreased with AHC compared with AC (25% decrease; p<0.05) and vehicle (50% decrease; p<0.0001). As research continues in this arena, cumulative lesion area should be included as a measure of efficacy in clinical trials of recurrent HSL therapies.
- Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2013 Dec 16. [Epub ahead of print]
- Historically, the primary target for research and treatment in recurrent herpes simplex labialis (HSL) has been limited to inhibiting herpes simplex virus (HSV) replication. Antiviral monotherapy, however, has proven only marginally effective in curtailing the duration and severity of recurrent lesi
- PMID 24342632
- Erythema multiforme associated with herpes labialis.
- Orgaz-Molina J, Arias-Santiago S.PMID: 23610016 [PubMed - indexed for MEDLINE] PMCID: PMC3826373 Free PMC ArticleImages from this publication.See all images (1)Free text
- CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.CMAJ.2013 Nov 5;185(16):1428. doi: 10.1503/cmaj.121307. Epub 2013 Apr 22.
- PMID 23610016
Japanese Journal
- 各種「ヘルペス」病原體ニ就テ （第一回報告） （承前）
- 江原 猪知郎
- 岡山医学会雑誌 38(432), 40-61, 1926-01-31
- … 1) Ich habe das Virus von Herpes febrilis, genitalis und zoster unter anderen Kontrollen in die Kornea, in den Hoden und subdural vom Kaninchen eingeimpft, und in jedem Organ entsprechende Entzündung hervorgenufen. … Der Hoden des Kaninchens spielt eine grosse Rolle beim Versuch des Herpes. … Durch Komplementbindungsreaktion mit diesem Antigen habe ich die Identität des Virus von Herpes simplex und zoster bestätigt. …
- NAID 120003673974
Related Links
- herpes /her·pes/ (her´pēz) any inflammatory skin disease marked by the formation of small vesicles in clusters; the term is usually restricted to such diseases caused by herpesviruses and is used alone to refer to h. simplex or to h ...
- Herpes febrilis information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues. ... Introduction: Herpes febrilis Description of Herpes febrilis Herpes febrilis: Related Topics These ...
★リンクテーブル★
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- 英
- herpes simplex、cold sore
- 同
- 単純疱疹、熱性疱疹 herpes febrilis
- 関
- 口唇ヘルペス、口辺ヘルペス。単純ヘルペスウイルス
[show details]
[★]
- 英
- herpes febrilis
- 関
- 単純ヘルペス